Gene description for SPP1
Gene name	secreted phosphoprotein 1
Gene symbol	SPP1
Other names/aliases	BNSP BSPI ETA-1 OPN
Species	Homo sapiens
Database cross references - SPP1
ExoCarta	ExoCarta_6696
Entrez Gene	6696
HGNC	11255
MIM	166490
UniProt	P10451
SPP1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for SPP1

Molecular Function     cytokine activity GO:0005125 IEA     extracellular matrix binding GO:0050840 IEA     protein binding GO:0005515 IPI Biological Process     extracellular matrix disassembly GO:0022617 TAS     inflammatory response GO:0006954 IEA     response to vitamin D GO:0033280 IDA     cell adhesion GO:0007155 IEA     osteoblast differentiation GO:0001649 IEA     extracellular matrix organization GO:0030198 TAS     decidualization GO:0046697 TAS     positive regulation of cell-substrate adhesion GO:0010811 IEA     response to steroid hormone GO:0048545 IEA     neutrophil chemotaxis GO:0030593 IEA     negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 IEA     positive regulation of bone resorption GO:0045780 IEA     biomineral tissue development GO:0031214 IEA     embryo implantation GO:0007566 TAS Subcellular Localization     extracellular space GO:0005615 IDA     perinuclear region of cytoplasm GO:0048471 IEA     apical part of cell GO:0045177 IEA     extracellular exosome GO:0070062 IDA     extracellular region GO:0005576 TAS     cell projection GO:0042995 IEA