Gene description for IGFBP5
Gene name	insulin-like growth factor binding protein 5
Gene symbol	IGFBP5
Other names/aliases	IBP5
Species	Homo sapiens
Database cross references - IGFBP5
ExoCarta	ExoCarta_3488
Vesiclepedia	VP_3488
Entrez Gene	3488
HGNC	5474
MIM	146734
UniProt	P24593
IGFBP5 identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894

Gene ontology annotations for IGFBP5

Molecular Function     protein binding GO:0005515 IPI     fibronectin binding GO:0001968 IBA     insulin-like growth factor I binding GO:0031994 IPI     insulin-like growth factor II binding GO:0031995 IBA Biological Process     cellular response to cAMP GO:0071320 IDA     regulation of glucose metabolic process GO:0010906 IEA     type B pancreatic cell proliferation GO:0044342 IEA     osteoblast differentiation GO:0001649 IEA     intracellular signal transduction GO:0035556 IEA     negative regulation of translation GO:0017148 IDA     mammary gland involution GO:0060056 IEA     negative regulation of smooth muscle cell proliferation GO:0048662 IDA     cellular response to organic cyclic compound GO:0071407 IDA     positive regulation of protein kinase B signaling GO:0051897 IEA     response to growth hormone GO:0060416 ISS     signal transduction GO:0007165 NAS     negative regulation of insulin-like growth factor receptor signaling pathway GO:0043569 IDA     negative regulation of osteoblast differentiation GO:0045668 IEA     negative regulation of smooth muscle cell migration GO:0014912 IDA     regulation of cell growth GO:0001558 IEA     positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 IEA     glucose metabolic process GO:0006006 IEA     glucose homeostasis GO:0042593 IEA     cellular protein metabolic process GO:0044267 TAS     skeletal muscle tissue growth GO:0048630 IEA     hair follicle morphogenesis GO:0031069 IEA     striated muscle cell differentiation GO:0051146 IEA     negative regulation of cell migration GO:0030336 IDA Subcellular Localization     extracellular space GO:0005615 IBA     extracellular region GO:0005576 TAS     intracellular GO:0005622 IEA     insulin-like growth factor binding protein complex GO:0016942 IC