Gene description for APH1A
Gene name	APH1A gamma secretase subunit
Gene symbol	APH1A
Other names/aliases	6530402N02Rik APH-1 APH-1A CGI-78
Species	Homo sapiens
Database cross references - APH1A
ExoCarta	ExoCarta_51107
Entrez Gene	51107
HGNC	29509
MIM	607629
UniProt	Q96BI3
APH1A identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for APH1A

Molecular Function     protein binding GO:0005515 IPI     endopeptidase activity GO:0004175 IEA Biological Process     axon guidance GO:0007411 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of catalytic activity GO:0043085 IDA     apoptotic signaling pathway GO:0097190 TAS     Notch receptor processing GO:0007220 TAS     protein processing GO:0016485 IDA     amyloid precursor protein catabolic process GO:0042987 TAS     metanephros development GO:0001656 IEA     membrane protein ectodomain proteolysis GO:0006509 IDA     membrane protein intracellular domain proteolysis GO:0031293 TAS     Notch signaling pathway GO:0007219 TAS     positive regulation of apoptotic process GO:0043065 TAS     ephrin receptor signaling pathway GO:0048013 TAS Subcellular Localization     membrane GO:0016020 IDA     integral component of plasma membrane GO:0005887 IDA     plasma membrane GO:0005886 TAS     endoplasmic reticulum membrane GO:0005789 IEA     endoplasmic reticulum GO:0005783 IDA     Golgi apparatus GO:0005794 IDA     Golgi cisterna membrane GO:0032580 IEA