Gene description for SNX25 |
Gene name |
sorting nexin 25 |
Gene symbol |
SNX25 |
Other names/aliases |
MSTP043 SBBI31 |
Species |
Homo sapiens |
Database cross references - SNX25 |
ExoCarta |
ExoCarta_83891 |
Entrez Gene |
83891 |
HGNC |
21883 |
UniProt |
Q9H3E2
|
SNX25 identified in exosomes derived from the following tissue/cell type |
Malignant pleural effusions
|
14975938
|
Neuroblastoma cells
|
25944692
|
Gene ontology annotations for SNX25 |
|
Experiment description of studies that identified SNX25 in exosomes |
1 |
Experiment ID |
51 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSP90
|
EV Cytosolic markers |
✔
MHCII
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
14975938
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of exosomes isolated from human malignant pleural effusions. |
Authors |
Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN |
Journal name |
AJRCMB
|
Publication year |
2004 |
Sample |
Malignant pleural effusions |
Sample name |
Pleural Fluid - Breast cancer |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [MALDI TOF] Western blotting |
|
|
2 |
Experiment ID |
224 |
ISEV standards |
✔
EM|AFM
|
EV Biophysical techniques |
✔
Alix|TSG101
|
EV Cytosolic markers |
✔
CD63|CD81
|
EV Membrane markers |
✔
GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25944692
|
Organism |
Homo sapiens |
Experiment description |
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes |
Authors |
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Neuroblastoma cells |
Sample name |
SH-SY5Y |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density |
1.10 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry Western blotting |
|
|
Protein-protein interactions for SNX25 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which SNX25 is involved |
No pathways found
|
|
|