Gene description for ANKS6
Gene name ankyrin repeat and sterile alpha motif domain containing 6
Gene symbol ANKS6
Other names/aliases ANKRD14
NPHP16
PKDR1
SAMD6
Species Homo sapiens
 Database cross references - ANKS6
ExoCarta ExoCarta_203286
Vesiclepedia VP_203286
Entrez Gene 203286
HGNC 26724
MIM 615370
UniProt Q68DC2  
 ANKS6 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ANKS6
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    in utero embryonic development GO:0001701 IEA
    kidney development GO:0001822 IEA
    determination of left/right symmetry GO:0007368 IEA
    heart development GO:0007507 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    ciliary inversin compartment GO:0097543 IEA
 Experiment description of studies that identified ANKS6 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ANKS6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATAD1 84896
Affinity Capture-MS Homo sapiens
2 C1GALT1 56913
Two-hybrid Homo sapiens
3 BET1 10282
Two-hybrid Homo sapiens
4 PRKY  
Affinity Capture-MS Homo sapiens
5 TMEM60  
Two-hybrid Homo sapiens
6 RAB7A 7879
Proximity Label-MS Homo sapiens
7 LAMTOR1 55004
Proximity Label-MS Homo sapiens
8 XPO1 7514
Affinity Capture-MS Homo sapiens
9 RTP2  
Two-hybrid Homo sapiens
10 EMP1  
Two-hybrid Homo sapiens
11 CALM2 805
Affinity Capture-MS Homo sapiens
12 ATG9A 79065
Proximity Label-MS Homo sapiens
13 SMIM1 388588
Two-hybrid Homo sapiens
14 LOC100507537  
Two-hybrid Homo sapiens
15 TMEM120B  
Two-hybrid Homo sapiens
16 AGTRAP 57085
Two-hybrid Homo sapiens
17 VAMP4 8674
Two-hybrid Homo sapiens
18 TIMM10  
Affinity Capture-MS Homo sapiens
19 CETN3  
Affinity Capture-MS Homo sapiens
20 EMD 2010
Two-hybrid Homo sapiens
21 CALM1 801
Affinity Capture-MS Homo sapiens
22 IGFBP5 3488
Two-hybrid Homo sapiens
23 CXADR 1525
Proximity Label-MS Homo sapiens
24 DDX58 23586
Affinity Capture-RNA Homo sapiens
25 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
26 C5 727
Two-hybrid Homo sapiens
27 UFL1 23376
Affinity Capture-MS Homo sapiens
28 NEK7 140609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 TIMM9  
Affinity Capture-MS Homo sapiens
30 ETS2  
Affinity Capture-MS Homo sapiens
31 BCL2L2 599
Two-hybrid Homo sapiens
32 DCAF7 10238
Affinity Capture-MS Homo sapiens
33 NEK8  
Affinity Capture-MS Homo sapiens
34 ANKS3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 KIF11 3832
Affinity Capture-MS Homo sapiens
36 DDRGK1 65992
Affinity Capture-MS Homo sapiens
37 CALM3 808
Affinity Capture-MS Homo sapiens
38 KRAS 3845
Proximity Label-MS Homo sapiens
39 DDX1 1653
Affinity Capture-MS Homo sapiens
40 MARCH5  
Two-hybrid Homo sapiens
41 PITPNC1  
Two-hybrid Homo sapiens
42 C19orf52  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANKS6 is involved
No pathways found





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