Experiment description of studies that identified BCL2L2 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for BCL2L2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 C6orf222   Two-hybrid Homo sapiens 2 G0S2   Two-hybrid Homo sapiens 3 CLDN7 1366 Two-hybrid Homo sapiens 4 BBC3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 Bcl2l11   Protein-peptide Mus musculus 6 UBE2H 7328 Affinity Capture-MS Homo sapiens 7 BHLHA9   Two-hybrid Homo sapiens 8 BMF   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 9 SGPL1 8879 Two-hybrid Homo sapiens 10 PRPF4B 8899 Affinity Capture-MS Homo sapiens 11 BAX 581 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 PABPC4 8761 Affinity Capture-MS Homo sapiens 13 C11orf57   Affinity Capture-MS Homo sapiens 14 BAD   Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens 15 ATP5J 522 Two-hybrid Homo sapiens 16 TP53 7157 Protein-peptide Homo sapiens 17 PANX1 24145 Two-hybrid Homo sapiens 18 CHODL 140578 Two-hybrid Homo sapiens 19 SLC39A6 25800 Two-hybrid Homo sapiens 20 ERVFRD-1   Two-hybrid Homo sapiens 21 PPP1CA 5499 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 22 THOC2 57187 Affinity Capture-MS Homo sapiens 23 APOC1   Two-hybrid Homo sapiens 24 MUC1 4582 Two-hybrid Homo sapiens 25 BID   Protein-peptide Homo sapiens Protein-peptide Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 BCL2L11   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Protein-peptide Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 27 THOC7 80145 Affinity Capture-MS Homo sapiens 28 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 29 TMX1 81542 Two-hybrid Homo sapiens 30 PARK2   Affinity Capture-Western Homo sapiens 31 CD79A   Two-hybrid Homo sapiens 32 STOM 2040 Two-hybrid Homo sapiens 33 SUSD3 203328 Two-hybrid Homo sapiens 34 NUPL2 11097 Affinity Capture-MS Homo sapiens 35 BIK   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Protein-peptide Homo sapiens Two-hybrid Homo sapiens 36 GORAB 92344 Two-hybrid Homo sapiens 37 BAK1 578 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 38 GPX8 493869 Two-hybrid Homo sapiens 39 CCDC155   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 40 SLC39A2   Two-hybrid Homo sapiens 41 TCF4   Two-hybrid Homo sapiens 42 CDH1 999 Proximity Label-MS Homo sapiens 43 C10orf67   Two-hybrid Homo sapiens 44 TMEM139   Two-hybrid Homo sapiens 45 GPR151   Two-hybrid Homo sapiens 46 HRK   Protein-peptide Homo sapiens 47 PINK1   Affinity Capture-Western Homo sapiens 48 PSCA 8000 Two-hybrid Homo sapiens 49 KCNJ6   Two-hybrid Homo sapiens 50 TRIM32 22954 Affinity Capture-Western Homo sapiens 51 LDLR 3949 Positive Genetic Homo sapiens 52 CISD2 493856 Two-hybrid Homo sapiens 53 SLC35E3   Two-hybrid Homo sapiens 54 Prmt6   Affinity Capture-MS Mus musculus 55 SLC27A2 11001 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 BNIP3 664 Two-hybrid Homo sapiens 57 CIDEB   Two-hybrid Homo sapiens 58 FATE1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 59 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 60 CEBPA   Protein-peptide Homo sapiens 61 LRRIQ1   Two-hybrid Homo sapiens 62 APOC2 344 Two-hybrid Homo sapiens 63 ANKS6 203286 Two-hybrid Homo sapiens 64 APOC4   Two-hybrid Homo sapiens View the network

Pathways in which BCL2L2 is involved

No pathways found