Gene description for NUPL2
Gene name nucleoporin like 2
Gene symbol NUPL2
Other names/aliases CG1
NLP-1
NLP_1
hCG1
Species Homo sapiens
 Database cross references - NUPL2
ExoCarta ExoCarta_11097
Entrez Gene 11097
HGNC 17010
UniProt O15504  
 NUPL2 identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for NUPL2
Molecular Function
    nuclear export signal receptor activity GO:0005049 TAS
    metal ion binding GO:0046872 IEA
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    viral process GO:0016032 TAS
    glucose transport GO:0015758 TAS
    viral transcription GO:0019083 TAS
    cellular protein metabolic process GO:0044267 TAS
    mitotic cell cycle GO:0000278 TAS
    transmembrane transport GO:0055085 TAS
    viral life cycle GO:0019058 TAS
    protein export from nucleus GO:0006611 TAS
    small molecule metabolic process GO:0044281 TAS
    gene expression GO:0010467 TAS
    regulation of cellular response to heat GO:1900034 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    protein sumoylation GO:0016925 TAS
    post-translational protein modification GO:0043687 TAS
    cellular response to heat GO:0034605 TAS
    mRNA transport GO:0051028 IEA
    hexose transport GO:0008645 TAS
    regulation of glucose transport GO:0010827 TAS
    cytokine-mediated signaling pathway GO:0019221 TAS
    carbohydrate metabolic process GO:0005975 TAS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 TAS
    nuclear pore GO:0005643 IEA
    nucleus GO:0005634 IDA
    nuclear membrane GO:0031965 IEA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified NUPL2 in exosomes
1
Experiment ID 196
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUPL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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