Gene description for PABPC4L
Gene name poly(A) binding protein, cytoplasmic 4-like
Gene symbol PABPC4L
Other names/aliases -
Species Homo sapiens
 Database cross references - PABPC4L
ExoCarta ExoCarta_132430
Vesiclepedia VP_132430
Entrez Gene 132430
HGNC 31955
 PABPC4L identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PABPC4L
Molecular Function
    mRNA 3'-UTR binding GO:0003730 IBA
    poly(A) binding GO:0008143 IBA
    poly(U) RNA binding GO:0008266 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IBA
    cytoplasmic stress granule GO:0010494 IBA
    ribonucleoprotein complex GO:1990904 IBA
 Experiment description of studies that identified PABPC4L in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PABPC4L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GPSM2  
Affinity Capture-MS Homo sapiens
2 Rmdn3  
Affinity Capture-MS Mus musculus
3 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 YBX1 4904
Affinity Capture-MS Homo sapiens
5 PAIP2B  
Affinity Capture-MS Homo sapiens
6 HNRNPC 3183
Affinity Capture-MS Homo sapiens
7 FASN 2194
Negative Genetic Homo sapiens
8 RNF151  
Affinity Capture-MS Homo sapiens
9 MAP7 9053
Affinity Capture-MS Homo sapiens
10 NUPL2 11097
Affinity Capture-MS Homo sapiens
11 ILF3 3609
Affinity Capture-MS Homo sapiens
12 RPL19 6143
Affinity Capture-MS Homo sapiens
13 ZNF346  
Affinity Capture-MS Homo sapiens
14 LARP4B 23185
Affinity Capture-MS Homo sapiens
15 LIN28A  
Affinity Capture-MS Homo sapiens
16 PABPC5 140886
Affinity Capture-MS Homo sapiens
17 ECT2 1894
Affinity Capture-MS Homo sapiens
18 RPL35 11224
Affinity Capture-MS Homo sapiens
19 RTP3  
Affinity Capture-MS Homo sapiens
20 LIN28B  
Affinity Capture-MS Homo sapiens
21 SOX2  
Affinity Capture-MS Homo sapiens
22 DGCR8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 THAP3  
Affinity Capture-MS Homo sapiens
24 RPL3 6122
Affinity Capture-MS Homo sapiens
25 Csde1 229663
Affinity Capture-MS Mus musculus
26 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
27 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
28 PRR3  
Affinity Capture-MS Homo sapiens
29 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 PEA15 8682
Affinity Capture-MS Homo sapiens
31 PABPC4 8761
Affinity Capture-MS Homo sapiens
32 GSPT1 2935
Affinity Capture-MS Homo sapiens
33 SRSF6 6431
Affinity Capture-MS Homo sapiens
34 PURG  
Affinity Capture-MS Homo sapiens
35 PAIP1 10605
Affinity Capture-MS Homo sapiens
36 KRR1 11103
Affinity Capture-MS Homo sapiens
37 Pqbp1  
Affinity Capture-MS Mus musculus
38 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 RPS24 6229
Affinity Capture-MS Homo sapiens
40 Rab3gap1  
Affinity Capture-MS Mus musculus
41 KIF23 9493
Affinity Capture-MS Homo sapiens
42 RPL31 6160
Affinity Capture-MS Homo sapiens
43 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
44 Chmp4c  
Affinity Capture-MS Mus musculus
45 RPL23A 6147
Affinity Capture-MS Homo sapiens
46 LYAR 55646
Affinity Capture-MS Homo sapiens
47 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 FTL 2512
Affinity Capture-MS Homo sapiens
49 CSDE1 7812
Affinity Capture-MS Homo sapiens
50 SRP14 6727
Affinity Capture-MS Homo sapiens
51 SRSF3 6428
Affinity Capture-MS Homo sapiens
52 RBMS2 5939
Affinity Capture-MS Homo sapiens
53 GLTSCR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 YBX2 51087
Affinity Capture-MS Homo sapiens
55 Sart1  
Affinity Capture-MS Mus musculus
56 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 FAM120A 23196
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PABPC4L is involved
No pathways found





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