Gene description for PABPC5
Gene name poly(A) binding protein, cytoplasmic 5
Gene symbol PABPC5
Other names/aliases PABP5
Species Homo sapiens
 Database cross references - PABPC5
ExoCarta ExoCarta_140886
Entrez Gene 140886
HGNC 13629
MIM 300407
UniProt Q96DU9  
 PABPC5 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for PABPC5
Molecular Function
    nucleotide binding GO:0000166 IEA
    RNA binding GO:0003723 IEA
Subcellular Localization
    mitochondrial matrix GO:0005759 IEA
 Experiment description of studies that identified PABPC5 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for PABPC5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PABPC5 is involved
No pathways found





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