Gene description for APOBEC3B
Gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Gene symbol APOBEC3B
Other names/aliases A3B
APOBEC1L
ARCD3
ARP4
DJ742C19.2
PHRBNL
bK150C2.2
Species Homo sapiens
 Database cross references - APOBEC3B
ExoCarta ExoCarta_9582
Entrez Gene 9582
HGNC 17352
MIM 607110
UniProt Q9UH17  
 APOBEC3B identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for APOBEC3B
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    deoxycytidine deaminase activity GO:0047844 IMP
    zinc ion binding GO:0008270 IEA
Biological Process
    innate immune response GO:0045087 IEA
    negative regulation of transposition GO:0010529 IDA
    metabolic process GO:0008152 IMP
    defense response to virus GO:0051607 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
 Experiment description of studies that identified APOBEC3B in exosomes
1
Experiment ID 274
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|RAB5A
EV Cytosolic markers
CD9|CD82|CD63|CD81
EV Membrane markers
AIF
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for APOBEC3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which APOBEC3B is involved
No pathways found





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