Gene description for Shcbp1
Gene name Shc SH2-domain binding protein 1
Gene symbol Shcbp1
Other names/aliases mPAL
Species Mus musculus
 Database cross references - Shcbp1
ExoCarta ExoCarta_20419
Entrez Gene 20419
UniProt Q9Z179  
 Shcbp1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Shcbp1
Molecular Function
    protein binding GO:0005515 IPI
    SH2 domain binding GO:0042169 IDA
Biological Process
    regulation of neural precursor cell proliferation GO:2000177 IMP
    fibroblast growth factor receptor signaling pathway GO:0008543 IMP
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Shcbp1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Shcbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Shcbp1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here