Gene description for GPC5
Gene name glypican 5
Gene symbol GPC5
Other names/aliases -
Species Homo sapiens
 Database cross references - GPC5
ExoCarta ExoCarta_2262
Entrez Gene 2262
HGNC 4453
MIM 602446
UniProt P78333  
 GPC5 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for GPC5
Molecular Function
    heparan sulfate proteoglycan binding GO:0043395 IEA
Biological Process
    glycosaminoglycan catabolic process GO:0006027 TAS
    chondroitin sulfate metabolic process GO:0030204 TAS
    retinoid metabolic process GO:0001523 TAS
    carbohydrate metabolic process GO:0005975 TAS
    small molecule metabolic process GO:0044281 TAS
    phototransduction, visible light GO:0007603 TAS
    glycosaminoglycan metabolic process GO:0030203 TAS
    glycosaminoglycan biosynthetic process GO:0006024 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 TAS
    extracellular space GO:0005615 IEA
    lysosomal lumen GO:0043202 TAS
    plasma membrane GO:0005886 TAS
    Golgi lumen GO:0005796 TAS
    proteinaceous extracellular matrix GO:0005578 IEA
    extracellular region GO:0005576 TAS
    anchored component of membrane GO:0031225 IEA
 Experiment description of studies that identified GPC5 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for GPC5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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