Gene description for PUM2
Gene name pumilio RNA-binding family member 2
Gene symbol PUM2
Other names/aliases PUMH2
PUML2
Species Homo sapiens
 Database cross references - PUM2
ExoCarta ExoCarta_23369
Vesiclepedia VP_23369
Entrez Gene 23369
HGNC 14958
MIM 607205
UniProt Q8TB72  
 PUM2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for PUM2
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
Biological Process
    stress granule assembly GO:0034063 IEA
    regulation of translation GO:0006417 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytoplasmic stress granule GO:0010494 ISS
    perinuclear region of cytoplasm GO:0048471 IDA
    nuclear membrane GO:0031965 IDA
 Experiment description of studies that identified PUM2 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PUM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PUM2 23369
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 NOS1  
Affinity Capture-Western Homo sapiens
3 NANOS1 340719
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which PUM2 is involved
No pathways found





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