Experiment description of studies that identified PNN in exosomes

1 Experiment ID 211 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix EV Cytosolic markers ✔ EpCAM|TFRC EV Membrane markers ✔ cytochrome c|GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 212 ISEV standards ✔ CEM EV Biophysical techniques ✔ TSG101|Alix EV Cytosolic markers ✔ EpCAM|TFRC EV Membrane markers ✔ Cytochrome C|GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PNN

Protein Interactor ExoCarta ID Identification method PubMed Species 1 NFKBIL1   Affinity Capture-MS Homo sapiens 2 SRSF4 6429 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 3 KRT8 3856 Invitro Homo sapiens Two-hybrid Homo sapiens 4 KRT18 3875 Invitro Homo sapiens Two-hybrid Homo sapiens 5 C6orf111   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 6 SRRM2 23524 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 7 PS1D   Two-hybrid Homo sapiens 8 PPIG   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 9 RNPS1 10921 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 10 KRT19 3880 Invitro Homo sapiens Two-hybrid Homo sapiens 11 PRPF4B 8899 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 12 CTBP1 1487 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens View the network

Pathways in which PNN is involved

No pathways found