Gene description for PABPC1L
Gene name poly(A) binding protein, cytoplasmic 1-like
Gene symbol PABPC1L
Other names/aliases C20orf119
PABPC1L1
dJ1069P2.3
ePAB
Species Homo sapiens
 Database cross references - PABPC1L
ExoCarta ExoCarta_80336
Entrez Gene 80336
HGNC 15797
UniProt Q4VXU2  
 PABPC1L identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for PABPC1L
Molecular Function
    RNA binding GO:0003723 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    oocyte maturation GO:0001556 IEA
    mRNA polyadenylation GO:0006378 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified PABPC1L in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for PABPC1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PABPC1L is involved
No pathways found





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