Gene description for YBX1
Gene name Y box binding protein 1
Gene symbol YBX1
Other names/aliases BP-8
CSDA2
CSDB
DBPB
MDR-NF1
NSEP-1
NSEP1
YB-1
YB1
Species Homo sapiens
 Database cross references - YBX1
ExoCarta ExoCarta_4904
Vesiclepedia VP_4904
Entrez Gene 4904
HGNC 8014
MIM 154030
UniProt P67809  
 YBX1 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for YBX1
Molecular Function
    nucleic acid binding GO:0003676 IBA
    DNA binding GO:0003677 TAS
    chromatin binding GO:0003682 IEA
    double-stranded DNA binding GO:0003690 TAS
    single-stranded DNA binding GO:0003697 IEA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IDA
    mRNA binding GO:0003729 IEA
    protein binding GO:0005515 IPI
    miRNA binding GO:0035198 IDA
    GTPase binding GO:0051020 IPI
    C5-methylcytidine-containing RNA reader activity GO:0062153 IDA
    sequence-specific double-stranded DNA binding GO:1990837 IDA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    in utero embryonic development GO:0001701 IEA
    regulation of DNA-templated transcription GO:0006355 IDA
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    epidermis development GO:0008544 ISS
    regulation of gene expression GO:0010468 IBA
    negative regulation of translation GO:0017148 ISS
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
    mRNA stabilization GO:0048255 IDA
    embryonic morphogenesis GO:0048598 ISS
    RNA transport GO:0050658 IMP
    tRNA transport GO:0051031 IMP
    negative regulation of striated muscle cell differentiation GO:0051154 IEA
    positive regulation of cell division GO:0051781 IEA
    CRD-mediated mRNA stabilization GO:0070934 IDA
    CRD-mediated mRNA stabilization GO:0070934 IMP
    cellular response to interleukin-7 GO:0098761 IEA
    negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900152 IDA
    protein localization to cytoplasmic stress granule GO:1903608 IMP
    miRNA transport GO:1990428 IDA
    positive regulation of cytoplasmic translation GO:2000767 IDA
    negative regulation of cellular senescence GO:2000773 ISS
Subcellular Localization
    P-body GO:0000932 IEA
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    U12-type spliceosomal complex GO:0005689 IDA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    cytoplasmic stress granule GO:0010494 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
    extracellular exosome GO:0070062 IDA
    CRD-mediated mRNA stability complex GO:0070937 IDA
    CRD-mediated mRNA stability complex GO:0070937 IPI
    histone pre-mRNA 3'end processing complex GO:0071204 ISS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified YBX1 in sEVs
1
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
28
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
37
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
48
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
49
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
50
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for YBX1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSAP58 388524
Affinity Capture-MS Homo sapiens
2 ISG15 9636
Affinity Capture-MS Homo sapiens
3 VAPB 9217
Affinity Capture-MS Homo sapiens
4 MACROD1 28992
Affinity Capture-MS Homo sapiens
5 ZNF346  
Affinity Capture-MS Homo sapiens
6 MRPL33  
Affinity Capture-MS Homo sapiens
7 RIN3  
Affinity Capture-MS Homo sapiens
8 PSMA4 5685
Co-fractionation Homo sapiens
9 ZNF668  
Affinity Capture-MS Homo sapiens
10 DYNC1I2 1781
Co-fractionation Homo sapiens
11 USP10 9100
Affinity Capture-MS Homo sapiens
12 EIF2B2 8892
Co-fractionation Homo sapiens
13 ACTC1 70
Affinity Capture-MS Homo sapiens
14 BRCA1 672
Affinity Capture-MS Homo sapiens
15 KIF20A 10112
Affinity Capture-MS Homo sapiens
16 MRPL27 51264
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CSNK2A1 1457
Biochemical Activity Homo sapiens
18 PRPF40A 55660
Reconstituted Complex Homo sapiens
19 SOX2  
Affinity Capture-MS Homo sapiens
20 OTUD3 23252
Affinity Capture-MS Homo sapiens
21 APEX1 328
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
22 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 WDR76  
Affinity Capture-MS Homo sapiens
24 PRDM9  
Affinity Capture-MS Homo sapiens
25 KIF23 9493
Affinity Capture-MS Homo sapiens
26 UBE2O 63893
Affinity Capture-MS Homo sapiens
27 SF3B1 23451
Co-fractionation Homo sapiens
28 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 CHCHD10  
Affinity Capture-MS Homo sapiens
30 POU5F1  
Affinity Capture-RNA Homo sapiens
31 SMC2 10592
Affinity Capture-MS Homo sapiens
32 RPS9 6203
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
33 PTCD1 26024
Affinity Capture-MS Homo sapiens
34 MECP2 4204
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
35 ARIH2 10425
Affinity Capture-MS Homo sapiens
36 NMT1 4836
Co-fractionation Homo sapiens
37 SREK1 140890
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
38 EEF1A1 1915
Co-fractionation Homo sapiens
39 KIF14 9928
Affinity Capture-MS Homo sapiens
40 EXOSC9 5393
Affinity Capture-MS Homo sapiens
41 RBMX 27316
Co-fractionation Homo sapiens
42 TFAP2A  
Reconstituted Complex Homo sapiens
43 HSPA9 3313
Co-fractionation Homo sapiens
44 CHMP4C 92421
Affinity Capture-MS Homo sapiens
45 AURKA 6790
Affinity Capture-MS Homo sapiens
46 LIN28B  
Affinity Capture-MS Homo sapiens
47 SRPK2 6733
Affinity Capture-MS Homo sapiens
48 MEPCE 56257
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
50 SRSF3 6428
Affinity Capture-MS Homo sapiens
51 YBX2 51087
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
52 TUFM 7284
Co-fractionation Homo sapiens
53 PURG  
Affinity Capture-MS Homo sapiens
54 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
55 PABPC1 26986
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
56 YAP1 10413
Affinity Capture-MS Homo sapiens
57 ACTN4 81
Co-fractionation Homo sapiens
58 FLOT1 10211
Co-fractionation Homo sapiens
59 RPL31 6160
Affinity Capture-MS Homo sapiens
60 SYNCRIP 10492
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
61 HACE1 57531
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
62 MAEL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
63 NOS2  
Affinity Capture-MS Homo sapiens
64 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
65 Mapk13  
Affinity Capture-MS Mus musculus
66 HECTD1 25831
Affinity Capture-MS Homo sapiens
67 CUL2 8453
Affinity Capture-MS Homo sapiens
68 MAGEB2 4113
Affinity Capture-MS Homo sapiens
69 PICALM 8301
Cross-Linking-MS (XL-MS) Homo sapiens
70 VPS37B 79720
Affinity Capture-MS Homo sapiens
71 MRPL41 64975
Affinity Capture-MS Homo sapiens
72 ANLN 54443
Affinity Capture-MS Homo sapiens
73 MRPL57  
Affinity Capture-MS Homo sapiens
74 HSPA5 3309
Co-fractionation Homo sapiens
75 ABT1 29777
Affinity Capture-MS Homo sapiens
76 DAP3 7818
Affinity Capture-MS Homo sapiens
77 STMN2  
Cross-Linking-MS (XL-MS) Homo sapiens
78 MRPL24  
Affinity Capture-MS Homo sapiens
79 IQCB1  
Affinity Capture-MS Homo sapiens
80 MRPL16  
Affinity Capture-MS Homo sapiens
81 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 RPL7L1 285855
Affinity Capture-MS Homo sapiens
84 ZC3H11A  
Affinity Capture-MS Homo sapiens
85 FN1 2335
Affinity Capture-MS Homo sapiens
86 MRPL47 57129
Affinity Capture-MS Homo sapiens
87 TUBA4A 7277
Co-fractionation Homo sapiens
88 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
89 CMSS1  
Affinity Capture-MS Homo sapiens
90 RPA3 6119
Proximity Label-MS Homo sapiens
91 LSM3 27258
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
92 AP2A2 161
Affinity Capture-MS Homo sapiens
93 PHF5A 84844
Co-fractionation Homo sapiens
94 HSPA1A 3303
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
95 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
96 CSDE1 7812
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
97 AKT1 207
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Co-localization Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
98 IRF1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
99 MRPL18 29074
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 PRKDC 5591
Co-fractionation Homo sapiens
101 RPS16 6217
Affinity Capture-MS Homo sapiens
102 PAIP1 10605
Affinity Capture-MS Homo sapiens
103 PSMB2 5690
Co-fractionation Homo sapiens
104 NRCAM  
Cross-Linking-MS (XL-MS) Homo sapiens
105 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 EIF3I 8668
Co-fractionation Homo sapiens
107 APOBEC3D  
Affinity Capture-MS Homo sapiens
108 SRSF9 8683
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
109 MRPS18C  
Affinity Capture-MS Homo sapiens
110 LSM14A 26065
Affinity Capture-MS Homo sapiens
111 COX5A 9377
Co-fractionation Homo sapiens
112 CAPZB 832
Affinity Capture-MS Homo sapiens
113 H2AFB3  
Affinity Capture-MS Homo sapiens
114 TRA2B 6434
Affinity Capture-MS Homo sapiens
115 SIRT1  
Affinity Capture-MS Homo sapiens
116 SSBP1 6742
Co-fractionation Homo sapiens
117 DYNC1H1 1778
Co-fractionation Homo sapiens
118 KRR1 11103
Affinity Capture-MS Homo sapiens
119 LARP7 51574
Affinity Capture-MS Homo sapiens
120 NEIL1  
Affinity Capture-MS Homo sapiens
121 RPS24 6229
Affinity Capture-MS Homo sapiens
122 NCL 4691
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
123 ALYREF 10189
Co-fractionation Homo sapiens
124 HNRNPL 3191
Co-fractionation Homo sapiens
125 EIF4B 1975
Co-fractionation Homo sapiens
126 ATP6V1E1 529
Co-fractionation Homo sapiens
127 SORT1 6272
Affinity Capture-MS Homo sapiens
128 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
129 CLTA 1211
Affinity Capture-MS Homo sapiens
130 GLTSCR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 AKR7A2 8574
Cross-Linking-MS (XL-MS) Homo sapiens
132 RPL23A 6147
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
133 SMURF2 64750
Affinity Capture-MS Homo sapiens
134 SNRPA1 6627
Co-fractionation Homo sapiens
135 MRPL28 10573
Affinity Capture-MS Homo sapiens
136 NOP10 55505
Affinity Capture-MS Homo sapiens
137 IFIT2 3433
Affinity Capture-MS Homo sapiens
138 LLPH  
Affinity Capture-MS Homo sapiens
139 RBMXL1  
Affinity Capture-MS Homo sapiens
140 H1FNT  
Affinity Capture-MS Homo sapiens
141 SPRTN  
Affinity Capture-MS Homo sapiens
142 HSPA6 3310
Co-fractionation Homo sapiens
143 EIF3K 27335
Co-fractionation Homo sapiens
144 BTF3 689
Affinity Capture-MS Homo sapiens
145 NOP56 10528
Affinity Capture-MS Homo sapiens
146 COPB2 9276
Co-fractionation Homo sapiens
147 ZFR 51663
Affinity Capture-MS Homo sapiens
148 MRPL50 54534
Affinity Capture-MS Homo sapiens
149 CAND1 55832
Affinity Capture-MS Homo sapiens
150 MRPL49 740
Affinity Capture-MS Homo sapiens
151 RPS3 6188
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
152 SURF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 B3GNT2 10678
Affinity Capture-MS Homo sapiens
154 ANKRD2  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
155 PRC1 9055
Affinity Capture-MS Homo sapiens
156 NPM1 4869
Affinity Capture-MS Homo sapiens
157 SRRM2 23524
Affinity Capture-MS Homo sapiens
158 OBSL1 23363
Affinity Capture-MS Homo sapiens
159 C1qbp 12261
Affinity Capture-MS Mus musculus
160 NR4A1  
Affinity Capture-MS Homo sapiens
161 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 MRPS7 51081
Affinity Capture-MS Homo sapiens
163 CUL1 8454
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
164 OASL 8638
Affinity Capture-MS Homo sapiens
165 ZNF184  
Affinity Capture-MS Homo sapiens
166 GSK3B 2932
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
167 LARP4B 23185
Affinity Capture-MS Homo sapiens
168 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 LMAN1 3998
Co-fractionation Homo sapiens
170 ACTA2 59
Protein-RNA Homo sapiens
171 SF3A2 8175
Affinity Capture-MS Homo sapiens
172 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 THAP3  
Affinity Capture-MS Homo sapiens
174 MRPL45 84311
Affinity Capture-MS Homo sapiens
175 RPL4 6124
Affinity Capture-MS Homo sapiens
176 WHSC1 7468
Affinity Capture-MS Homo sapiens
177 UBAP2L 9898
Co-fractionation Homo sapiens
178 BAG6 7917
Affinity Capture-MS Homo sapiens
179 ZBTB48  
Affinity Capture-MS Homo sapiens
180 SNRNP200 23020
Co-fractionation Homo sapiens
181 SNRPB 6628
Co-fractionation Homo sapiens
182 SNRPD1 6632
Co-fractionation Homo sapiens
183 MRPL51 51258
Affinity Capture-MS Homo sapiens
184 REXO4  
Affinity Capture-MS Homo sapiens
185 GAPDH 2597
Co-fractionation Homo sapiens
186 MRPL3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 MAGOH 4116
Affinity Capture-MS Homo sapiens
188 RPLP0 6175
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
189 TRIM31  
Affinity Capture-MS Homo sapiens
190 Ksr1  
Affinity Capture-MS Mus musculus
191 CYLD  
Affinity Capture-MS Homo sapiens
192 NFX1  
Affinity Capture-MS Homo sapiens
193 OGT 8473
Reconstituted Complex Homo sapiens
194 RSL1D1 26156
Affinity Capture-MS Homo sapiens
195 FGFBP1 9982
Affinity Capture-MS Homo sapiens
196 HNRNPD 3184
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
197 MRPL44  
Affinity Capture-MS Homo sapiens
198 TUBB 203068
Co-fractionation Homo sapiens
199 ZEB1  
Affinity Capture-MS Homo sapiens
200 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 XPO1 7514
Affinity Capture-MS Homo sapiens
202 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 MRPS11  
Affinity Capture-MS Homo sapiens
204 MRPL9 65005
Affinity Capture-MS Homo sapiens
205 SRSF5 6430
Affinity Capture-MS Homo sapiens
206 EGFR 1956
Affinity Capture-MS Homo sapiens
207 GAS2L3  
Cross-Linking-MS (XL-MS) Homo sapiens
208 FUS 2521
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
209 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 BAG1 573
Affinity Capture-MS Homo sapiens
211 GZF1  
Affinity Capture-MS Homo sapiens
212 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 CUL7 9820
Affinity Capture-MS Homo sapiens
214 FKBP3 2287
Co-fractionation Homo sapiens
215 DDRGK1 65992
Affinity Capture-MS Homo sapiens
216 BMI1  
Affinity Capture-MS Homo sapiens
217 H2AFB2  
Affinity Capture-MS Homo sapiens
218 MRPS17 51373
Affinity Capture-MS Homo sapiens
219 NELFB 25920
Co-fractionation Homo sapiens
220 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
221 RPL26 6154
Affinity Capture-MS Homo sapiens
222 FTSJ3 117246
Affinity Capture-MS Homo sapiens
223 EIF3H 8667
Affinity Capture-MS Homo sapiens
224 RPL19 6143
Affinity Capture-MS Homo sapiens
225 PA2G4 5036
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
226 RPL13 6137
Affinity Capture-MS Homo sapiens
227 SURF6  
Affinity Capture-MS Homo sapiens
228 RAD21 5885
Affinity Capture-Western Homo sapiens
229 MKRN1 23608
Affinity Capture-MS Homo sapiens
230 SPOP  
Affinity Capture-MS Homo sapiens
231 RNF151  
Affinity Capture-MS Homo sapiens
232 PARP1 142
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
233 MRPS22 56945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
235 IREB2 3658
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
236 PSMC4 5704
Co-fractionation Homo sapiens
237 PTBP1 5725
Co-fractionation Homo sapiens
238 RPAP2  
Affinity Capture-MS Homo sapiens
239 UTP23  
Affinity Capture-MS Homo sapiens
240 PSME3 10197
Affinity Capture-MS Homo sapiens
241 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
242 CDK5RAP1  
Affinity Capture-MS Homo sapiens
243 BUB3 9184
Affinity Capture-MS Homo sapiens
244 NIFK 84365
Affinity Capture-MS Homo sapiens
245 HNRNPK 3190
Co-fractionation Homo sapiens
246 UNK  
Affinity Capture-RNA Homo sapiens
247 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 HOXC-AS3  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
249 RBM23  
Affinity Capture-MS Homo sapiens
250 BAG5 9529
Affinity Capture-MS Homo sapiens
251 YBX3 8531
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
252 RPL7A 6130
Affinity Capture-MS Homo sapiens
253 C1QBP 708
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 KRAS 3845
Affinity Capture-MS Homo sapiens
255 IFIT1 3434
Affinity Capture-MS Homo sapiens
256 PRMT1 3276
Affinity Capture-MS Homo sapiens
257 MRPS9 64965
Affinity Capture-MS Homo sapiens
258 SIAH1  
Affinity Capture-Western Homo sapiens
259 NUPL2 11097
Affinity Capture-MS Homo sapiens
260 MRPS27 23107
Affinity Capture-MS Homo sapiens
261 UBE2H 7328
Affinity Capture-MS Homo sapiens
262 HNRNPC 3183
Affinity Capture-MS Homo sapiens
263 RPL26L1 51121
Affinity Capture-MS Homo sapiens
264 FBXO33  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
265 MRPL30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 MRPL17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 LARP1B 55132
Affinity Capture-MS Homo sapiens
268 RPS19 6223
Affinity Capture-MS Homo sapiens
269 SSB 6741
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
271 HNRNPR 10236
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
272 LSM14B 149986
Affinity Capture-MS Homo sapiens
273 APBB1  
Reconstituted Complex Homo sapiens
274 RPS6KB2  
Affinity Capture-MS Homo sapiens
275 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
276 DIMT1 27292
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
277 HNRNPAB 3182
Co-fractionation Homo sapiens
278 GSPT2 23708
Affinity Capture-MS Homo sapiens
279 DYNC1LI2 1783
Co-fractionation Homo sapiens
280 ZNF514  
Affinity Capture-MS Homo sapiens
281 CHCHD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 MRPS5 64969
Affinity Capture-MS Homo sapiens
283 IQGAP1 8826
Affinity Capture-MS Homo sapiens
284 EWSR1 2130
Affinity Capture-Western Homo sapiens
285 PSMC2 5701
Co-fractionation Homo sapiens
286 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
287 ITGA4 3676
Affinity Capture-MS Homo sapiens
288 MRPL39 54148
Affinity Capture-MS Homo sapiens
289 ATG16L1 55054
Affinity Capture-MS Homo sapiens
290 NHP2 55651
Affinity Capture-MS Homo sapiens
291 TFCP2 7024
Affinity Capture-MS Homo sapiens
292 MRPL4 51073
Affinity Capture-MS Homo sapiens
293 YAF2  
Affinity Capture-MS Homo sapiens
294 PABPC4 8761
Affinity Capture-MS Homo sapiens
295 MTERF3  
Affinity Capture-MS Homo sapiens
296 RBM8A 9939
Affinity Capture-MS Homo sapiens
297 RBM19 9904
Affinity Capture-MS Homo sapiens
298 HSPA8 3312
Co-fractionation Homo sapiens
299 MAP2 4133
Co-fractionation Homo sapiens
300 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 INSIG2  
Affinity Capture-MS Homo sapiens
302 BRIX1 55299
Affinity Capture-MS Homo sapiens
303 MRPS25 64432
Affinity Capture-MS Homo sapiens
304 PSMB4 5692
Co-fractionation Homo sapiens
305 ZCCHC9  
Affinity Capture-MS Homo sapiens
306 JAM2  
Two-hybrid Homo sapiens
307 CUL4B 8450
Affinity Capture-MS Homo sapiens
308 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 PHAX  
Cross-Linking-MS (XL-MS) Homo sapiens
310 RPS10 6204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 ANKRD35  
Affinity Capture-MS Homo sapiens
312 BARD1 580
Affinity Capture-MS Homo sapiens
313 NTRK1 4914
Affinity Capture-MS Homo sapiens
314 U2AF2 11338
Affinity Capture-MS Homo sapiens
315 DHX9 1660
Affinity Capture-MS Homo sapiens
316 MRPL11 65003
Affinity Capture-MS Homo sapiens
317 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
318 MRPL2 51069
Affinity Capture-MS Homo sapiens
319 PURB 5814
Affinity Capture-MS Homo sapiens
320 RNU12 267010
Affinity Capture-MS Homo sapiens
321 LARP1 23367
Affinity Capture-MS Homo sapiens
322 PAIP2B  
Affinity Capture-MS Homo sapiens
323 RBBP6 5930
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
324 SF3B2 10992
Co-fractionation Homo sapiens
325 MRPL40 64976
Affinity Capture-MS Homo sapiens
326 THUMPD1 55623
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
327 METTL14  
Affinity Capture-MS Homo sapiens
328 ECT2 1894
Affinity Capture-MS Homo sapiens
329 MRPL10 124995
Affinity Capture-MS Homo sapiens
330 RNU11 26824
Affinity Capture-MS Homo sapiens
331 EEF2 1938
Co-fractionation Homo sapiens
332 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
333 TRAF6 7189
Two-hybrid Homo sapiens
334 SPICE1  
Affinity Capture-MS Homo sapiens
335 PSMA2 5683
Co-fractionation Homo sapiens
336 ZC3H8  
Affinity Capture-MS Homo sapiens
337 FBXO6 26270
Affinity Capture-MS Homo sapiens
338 ACE2 59272
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
339 MRPS28  
Affinity Capture-MS Homo sapiens
340 ZNF777  
Affinity Capture-MS Homo sapiens
341 GIGYF2 26058
Affinity Capture-MS Homo sapiens
342 PRR3  
Affinity Capture-MS Homo sapiens
343 CBX6  
Affinity Capture-MS Homo sapiens
344 MRPL19 9801
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 RPL22 6146
Affinity Capture-MS Homo sapiens
346 SKIV2L2 23517
Co-fractionation Homo sapiens
347 MATR3 9782
Co-fractionation Homo sapiens
348 HDLBP 3069
Affinity Capture-MS Homo sapiens
349 RNF2  
Affinity Capture-MS Homo sapiens
350 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
351 HSPD1 3329
Co-fractionation Homo sapiens
352 MRPL38  
Affinity Capture-MS Homo sapiens
353 RBMS2 5939
Affinity Capture-MS Homo sapiens
354 C3orf17  
Affinity Capture-MS Homo sapiens
355 HIF1A 3091
Affinity Capture-MS Homo sapiens
356 ZNF574  
Affinity Capture-MS Homo sapiens
357 EIF2S1 1965
Co-fractionation Homo sapiens
358 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
359 FBXW11  
Affinity Capture-MS Homo sapiens
360 CDC20 991
Affinity Capture-MS Homo sapiens
361 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
362 AGO1  
Affinity Capture-MS Homo sapiens
363 ICT1 3396
Affinity Capture-MS Homo sapiens
364 MCM5 4174
Affinity Capture-MS Homo sapiens
365 ALDH1B1 219
Co-fractionation Homo sapiens
366 G3BP1 10146
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
367 PTBP3 9991
Affinity Capture-MS Homo sapiens
368 MRPS10 55173
Affinity Capture-MS Homo sapiens
369 MTHFD1 4522
Co-fractionation Homo sapiens
370 DDX58 23586
Affinity Capture-RNA Homo sapiens
371 PCNA 5111
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
372 UFL1 23376
Affinity Capture-MS Homo sapiens
373 MRPS18B 28973
Affinity Capture-MS Homo sapiens
374 API5 8539
Affinity Capture-MS Homo sapiens
375 GLI4  
Affinity Capture-MS Homo sapiens
376 LCP2 3937
Two-hybrid Homo sapiens
377 RPS7 6201
Cross-Linking-MS (XL-MS) Homo sapiens
378 SERBP1 26135
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
379 RPL36AL 6166
Affinity Capture-MS Homo sapiens
380 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
381 UBA6 55236
Co-fractionation Homo sapiens
382 UBE2V2 7336
Affinity Capture-MS Homo sapiens
383 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
384 EP300 2033
Affinity Capture-Western Homo sapiens
385 HLA-C 3107
Two-hybrid Homo sapiens
386 GNL2 29889
Affinity Capture-MS Homo sapiens
387 RPSA 3921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
388 INSIG1  
Affinity Capture-MS Homo sapiens
389 RIT1 6016
Negative Genetic Homo sapiens
390 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
391 AP2B1 163
Proximity Label-MS Homo sapiens
392 PAXIP1  
Affinity Capture-MS Homo sapiens
393 RPS3A 6189
Affinity Capture-MS Homo sapiens
394 CPOX 1371
Co-fractionation Homo sapiens
395 ZNF324B  
Affinity Capture-MS Homo sapiens
396 FAM192A  
Affinity Capture-MS Homo sapiens
397 MAGEL2  
Proximity Label-MS Homo sapiens
398 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
399 RPL13A 23521
Affinity Capture-MS Homo sapiens
400 TRUB2  
Affinity Capture-MS Homo sapiens
401 NGRN  
Affinity Capture-MS Homo sapiens
402 TSG101 7251
Affinity Capture-Western Homo sapiens
403 RPL10 6134
Affinity Capture-MS Homo sapiens
404 MRPL37 51253
Affinity Capture-MS Homo sapiens
405 HABP4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
406 CALM1 801
Reconstituted Complex Homo sapiens
407 TROVE2 6738
Co-fractionation Homo sapiens
408 MRPL52  
Affinity Capture-MS Homo sapiens
409 SNRPD2 6633
Co-fractionation Homo sapiens
410 TMPO 7112
Affinity Capture-MS Homo sapiens
411 ILF2 3608
Co-fractionation Homo sapiens
412 GSK3A 2931
Affinity Capture-MS Homo sapiens
413 KIAA1429 25962
Affinity Capture-MS Homo sapiens
414 RPS6KA3 6197
Biochemical Activity Homo sapiens
415 RPS20 6224
Proximity Label-MS Homo sapiens
416 MRPL20 55052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 PABPC4L 132430
Affinity Capture-MS Homo sapiens
418 MRPL23 6150
Affinity Capture-MS Homo sapiens
419 COPS5 10987
Affinity Capture-MS Homo sapiens
420 FBXW7  
Affinity Capture-MS Homo sapiens
421 HGS 9146
Cross-Linking-MS (XL-MS) Homo sapiens
422 MRPS24 64951
Affinity Capture-MS Homo sapiens
423 MRPL12 6182
Affinity Capture-MS Homo sapiens
424 SNRPC 6631
Affinity Capture-MS Homo sapiens
425 IFIT3 3437
Affinity Capture-MS Homo sapiens
426 MRPS21  
Affinity Capture-MS Homo sapiens
427 MYCN  
Affinity Capture-MS Homo sapiens
428 NEDD8 4738
Affinity Capture-MS Homo sapiens
429 KRI1  
Affinity Capture-MS Homo sapiens
430 CTCF  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
431 CPEB1  
Affinity Capture-MS Homo sapiens
432 MAPK1 5594
Biochemical Activity Homo sapiens
433 MRPS30 10884
Affinity Capture-MS Homo sapiens
434 MRPL13  
Affinity Capture-MS Homo sapiens
435 FARS2 10667
Affinity Capture-MS Homo sapiens
436 MRPL32 64983
Affinity Capture-MS Homo sapiens
437 KHDRBS2  
Affinity Capture-MS Homo sapiens
438 MRPS34 65993
Affinity Capture-MS Homo sapiens
439 SMU1 55234
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
440 STAU1 6780
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
441 SRSF6 6431
Affinity Capture-MS Homo sapiens
442 PTCD3 55037
Affinity Capture-MS Homo sapiens
443 IFI16 3428
Affinity Capture-MS Homo sapiens
444 PRKACB 5567
Affinity Capture-MS Homo sapiens
445 DDX54 79039
Affinity Capture-MS Homo sapiens
446 DDX1 1653
Co-fractionation Homo sapiens
447 MRPL22  
Affinity Capture-MS Homo sapiens
448 UPF1 5976
Affinity Capture-MS Homo sapiens
449 CEBPA  
Protein-peptide Homo sapiens
450 FGF13  
Affinity Capture-MS Homo sapiens
451 MRPS33  
Affinity Capture-MS Homo sapiens
452 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
453 RPS6KA1 6195
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
454 RPF1  
Affinity Capture-MS Homo sapiens
455 ELAVL2 1993
Affinity Capture-MS Homo sapiens
456 DDX6 1656
Affinity Capture-MS Homo sapiens
457 MRPL21 219927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
458 FANCD2  
Affinity Capture-MS Homo sapiens
459 SRSF7 6432
Affinity Capture-MS Homo sapiens
460 NDUFA9 4704
Co-fractionation Homo sapiens
461 RPL35 11224
Affinity Capture-MS Homo sapiens
462 CTNNB1 1499
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
463 SRSF1 6426
Affinity Capture-MS Homo sapiens
464 RPS6 6194
Affinity Capture-MS Homo sapiens
465 RPL3 6122
Affinity Capture-MS Homo sapiens
466 RPL7 6129
Affinity Capture-MS Homo sapiens
467 SUZ12  
Affinity Capture-MS Homo sapiens
468 MRPL15 29088
Affinity Capture-MS Homo sapiens
469 AURKB 9212
Affinity Capture-MS Homo sapiens
470 MRPL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
471 AGO4  
Affinity Capture-MS Homo sapiens
472 IL7R  
Protein-RNA Homo sapiens
473 DKC1 1736
Affinity Capture-MS Homo sapiens
474 HNRNPA1 3178
Co-fractionation Homo sapiens
475 USP47 55031
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
476 FASTKD2  
Affinity Capture-MS Homo sapiens
477 PABPC5 140886
Affinity Capture-MS Homo sapiens
478 EPRS 2058
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
479 PSMB5 5693
Co-fractionation Homo sapiens
480 SF3B3 23450
Co-fractionation Homo sapiens
481 BMP4 652
Affinity Capture-MS Homo sapiens
482 ZC3H3  
Affinity Capture-MS Homo sapiens
483 MDM2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
484 CCDC8  
Affinity Capture-MS Homo sapiens
485 TRIM71  
Affinity Capture-MS Homo sapiens
486 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
487 Cbx1  
Affinity Capture-MS Mus musculus
488 DHX15 1665
Co-fractionation Homo sapiens
489 MRPL42  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
490 ARRB2 409
Affinity Capture-MS Homo sapiens
491 MRPS2 51116
Affinity Capture-MS Homo sapiens
492 PPIG 9360
Affinity Capture-MS Homo sapiens
493 MRPS31  
Affinity Capture-MS Homo sapiens
494 HNRNPA2B1 3181
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
495 SMURF1 57154
Affinity Capture-MS Homo sapiens
496 SRP72 6731
Affinity Capture-MS Homo sapiens
497 NSA2  
Affinity Capture-MS Homo sapiens
498 EIF4A3 9775
Affinity Capture-MS Homo sapiens
499 SQSTM1 8878
Proximity Label-MS Homo sapiens
500 EZH2  
Affinity Capture-MS Homo sapiens
501 ARRB1 408
Affinity Capture-MS Homo sapiens
502 TRIP4 9325
Affinity Capture-MS Homo sapiens
503 CDK9 1025
Affinity Capture-MS Homo sapiens
504 PINK1  
Affinity Capture-MS Homo sapiens
505 RPS8 6202
Affinity Capture-MS Homo sapiens
506 GRSF1 2926
Proximity Label-MS Homo sapiens
507 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
508 HNRNPU 3192
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
509 C9orf72  
Affinity Capture-MS Homo sapiens
510 IVNS1ABP  
Affinity Capture-MS Homo sapiens
511 MRPS18A  
Affinity Capture-MS Homo sapiens
512 RPL17 6139
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here