Gene description for MRPS24
Gene name mitochondrial ribosomal protein S24
Gene symbol MRPS24
Other names/aliases HSPC335
MRP-S24
S24mt
bMRP-47
bMRP47
Species Homo sapiens
 Database cross references - MRPS24
ExoCarta ExoCarta_64951
Vesiclepedia VP_64951
Entrez Gene 64951
HGNC 14510
MIM 611986
UniProt Q96EL2  
 MRPS24 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for MRPS24
Molecular Function
    structural constituent of ribosome GO:0003735 ISS
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    mitochondrial translational initiation GO:0070124 TAS
    translation GO:0006412 ISS
    biological_process GO:0008150 ND
    organelle organization GO:0006996 TAS
    mitochondrial translation GO:0032543 TAS
    mitochondrial translational termination GO:0070126 TAS
    mitochondrial translational elongation GO:0070125 TAS
Subcellular Localization
    mitochondrial small ribosomal subunit GO:0005763 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial large ribosomal subunit GO:0005762 ISS
 Experiment description of studies that identified MRPS24 in exosomes
1
Experiment ID 235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for MRPS24
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DDX56  
Affinity Capture-MS Homo sapiens
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