Gene description for MRPS23
Gene name mitochondrial ribosomal protein S23
Gene symbol MRPS23
Other names/aliases CGI-138
HSPC329
MRP-S23
Species Homo sapiens
 Database cross references - MRPS23
ExoCarta ExoCarta_51649
Vesiclepedia VP_51649
Entrez Gene 51649
HGNC 14509
MIM 611985
UniProt Q9Y3D9  
 MRPS23 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for MRPS23
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IEA
    protein binding GO:0005515 IPI
Biological Process
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 NAS
    nuclear membrane GO:0031965 IDA
 Experiment description of studies that identified MRPS23 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MRPS23
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 RBM42  
Affinity Capture-MS Homo sapiens
3 CDC14B 8555
Affinity Capture-MS Homo sapiens
4 PDHA1 5160
Proximity Label-MS Homo sapiens
5 MRPS27 23107
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
6 CPSF6 11052
Affinity Capture-MS Homo sapiens
7 UBE2H 7328
Affinity Capture-MS Homo sapiens
8 SLIRP 81892
Proximity Label-MS Homo sapiens
9 QARS 5859
Co-fractionation Homo sapiens
10 CTPS2 56474
Affinity Capture-MS Homo sapiens
11 ZNF324B  
Affinity Capture-MS Homo sapiens
12 LHX2  
Proximity Label-MS Homo sapiens
13 TRUB2  
Proximity Label-MS Homo sapiens
14 MTG2  
Proximity Label-MS Homo sapiens
15 NGRN  
Proximity Label-MS Homo sapiens
16 CHCHD1  
Proximity Label-MS Homo sapiens
17 KLF12  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 HSPB1 3315
Two-hybrid Homo sapiens
19 CAND1 55832
Affinity Capture-MS Homo sapiens
20 RPUSD4 84881
Proximity Label-MS Homo sapiens
21 DNAJC15  
Proximity Label-MS Homo sapiens
22 MTRF1  
Proximity Label-MS Homo sapiens
23 GFM2 84340
Proximity Label-MS Homo sapiens
24 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CCDC90B  
Proximity Label-MS Homo sapiens
26 AMOTL1 154810
Affinity Capture-MS Homo sapiens
27 LRPPRC 10128
Proximity Label-MS Homo sapiens
28 KIAA1429 25962
Affinity Capture-MS Homo sapiens
29 CAPZB 832
Affinity Capture-MS Homo sapiens
30 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
31 OTC 5009
Proximity Label-MS Homo sapiens
32 MCU 90550
Proximity Label-MS Homo sapiens
33 CRYZ 1429
Proximity Label-MS Homo sapiens
34 TFAM 7019
Proximity Label-MS Homo sapiens
35 PMPCA 23203
Proximity Label-MS Homo sapiens
36 C8orf82  
Proximity Label-MS Homo sapiens
37 CYB5R1 51706
Co-fractionation Homo sapiens
38 MRPS5 64969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 HINT2 84681
Proximity Label-MS Homo sapiens
40 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 NPM1 4869
Affinity Capture-MS Homo sapiens
42 SRRM2 23524
Affinity Capture-MS Homo sapiens
43 DDRGK1 65992
Affinity Capture-MS Homo sapiens
44 KLF15  
Affinity Capture-MS Homo sapiens
45 ARMC8 25852
Affinity Capture-MS Homo sapiens
46 RPS9 6203
Affinity Capture-MS Homo sapiens
47 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 SURF1  
Proximity Label-MS Homo sapiens
49 SRSF3 6428
Affinity Capture-MS Homo sapiens
50 DYNLL1 8655
Affinity Capture-MS Homo sapiens
51 EXD2  
Proximity Label-MS Homo sapiens
52 TULP3 7289
Affinity Capture-MS Homo sapiens
53 ITGA4 3676
Affinity Capture-MS Homo sapiens
54 KLF4  
Affinity Capture-MS Homo sapiens
55 VCAM1 7412
Affinity Capture-MS Homo sapiens
56 CEP57  
Affinity Capture-MS Homo sapiens
57 MRPS7 51081
Affinity Capture-MS Homo sapiens
58 MECP2 4204
Affinity Capture-MS Homo sapiens
59 TLX3  
Proximity Label-MS Homo sapiens
60 CUL1 8454
Affinity Capture-MS Homo sapiens
61 KLF16  
Affinity Capture-MS Homo sapiens
62 PMPCB 9512
Proximity Label-MS Homo sapiens
63 TACO1  
Proximity Label-MS Homo sapiens
64 FASTKD2  
Proximity Label-MS Homo sapiens
65 MTIF2 4528
Proximity Label-MS Homo sapiens
66 AMOT  
Affinity Capture-MS Homo sapiens
67 ARHGEF15  
Affinity Capture-MS Homo sapiens
68 FAM120A 23196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 MTERF3  
Proximity Label-MS Homo sapiens
70 HSPA8 3312
Co-fractionation Homo sapiens
71 MDH2 4191
Proximity Label-MS Homo sapiens
72 TFB1M  
Affinity Capture-MS Homo sapiens
73 SOX6  
Affinity Capture-MS Homo sapiens
74 MRPS25 64432
Affinity Capture-MS Homo sapiens
75 CDKN2AIP  
Affinity Capture-MS Homo sapiens
76 POLD1 5424
Affinity Capture-MS Homo sapiens
77 C6orf203  
Proximity Label-MS Homo sapiens
78 ZNF133  
Affinity Capture-MS Homo sapiens
79 COX15 1355
Proximity Label-MS Homo sapiens
80 FASTKD5  
Proximity Label-MS Homo sapiens
81 RPL26 6154
Affinity Capture-MS Homo sapiens
82 PARK2  
Affinity Capture-MS Homo sapiens
83 MRPS34 65993
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
84 ERBB3 2065
Affinity Capture-MS Homo sapiens
85 ZBTB47  
Affinity Capture-MS Homo sapiens
86 SNRPA 6626
Affinity Capture-MS Homo sapiens
87 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 POLRMT 5442
Affinity Capture-MS Homo sapiens
89 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
90 TUFM 7284
Proximity Label-MS Homo sapiens
91 TPD52 7163
Affinity Capture-MS Homo sapiens
92 PTCD3 55037
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 HSCB 150274
Proximity Label-MS Homo sapiens
94 VCP 7415
Affinity Capture-MS Homo sapiens
95 COPS5 10987
Affinity Capture-MS Homo sapiens
96 MRPS6  
Affinity Capture-MS Homo sapiens
97 CCDC109B 55013
Proximity Label-MS Homo sapiens
98 RAD18  
Affinity Capture-MS Homo sapiens
99 DNAJA1 3301
Co-fractionation Homo sapiens
100 MOV10 4343
Affinity Capture-RNA Homo sapiens
101 NOA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 MTFMT  
Proximity Label-MS Homo sapiens
103 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
104 CEP76  
Affinity Capture-MS Homo sapiens
105 AGPS 8540
Co-fractionation Homo sapiens
106 HSD17B8  
Affinity Capture-MS Homo sapiens
107 MRPS33  
Affinity Capture-MS Homo sapiens
108 NPM3 10360
Affinity Capture-MS Homo sapiens
109 HIST1H1E 3008
Co-fractionation Homo sapiens
110 ATG16L1 55054
Affinity Capture-MS Homo sapiens
111 TLX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 YBX3 8531
Affinity Capture-MS Homo sapiens
113 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 RBM39 9584
Affinity Capture-MS Homo sapiens
115 DNAJC21  
Affinity Capture-MS Homo sapiens
116 MRRF  
Proximity Label-MS Homo sapiens
117 ABT1 29777
Affinity Capture-MS Homo sapiens
118 MRPS12  
Proximity Label-MS Homo sapiens
119 SRSF7 6432
Affinity Capture-MS Homo sapiens
120 DAP3 7818
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 TLX1  
Affinity Capture-MS Homo sapiens
122 MRPS35 60488
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 RC3H2  
Affinity Capture-MS Homo sapiens
124 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 MTIF3  
Proximity Label-MS Homo sapiens
126 RPL35 11224
Affinity Capture-MS Homo sapiens
127 MRPS14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
129 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 ERAL1  
Affinity Capture-MS Homo sapiens
131 RMND1 55005
Proximity Label-MS Homo sapiens
132 B4galt1  
Affinity Capture-MS Mus musculus
133 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 DHX30 22907
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 MYC  
Affinity Capture-MS Homo sapiens
136 Ect2  
Affinity Capture-MS Mus musculus
137 MRPS28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 C12orf65  
Proximity Label-MS Homo sapiens
139 MYCN  
Affinity Capture-MS Homo sapiens
140 CEP250 11190
Affinity Capture-MS Homo sapiens
141 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
142 MTG1  
Proximity Label-MS Homo sapiens
143 PSPC1 55269
Affinity Capture-MS Homo sapiens
144 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
145 TSFM 10102
Proximity Label-MS Homo sapiens
146 ACAD9 28976
Proximity Label-MS Homo sapiens
147 VWA8 23078
Proximity Label-MS Homo sapiens
148 USHBP1  
Two-hybrid Homo sapiens
149 MRPS17 51373
Affinity Capture-MS Homo sapiens
150 METTL15  
Proximity Label-MS Homo sapiens
151 MCUR1 63933
Proximity Label-MS Homo sapiens
152 DDX55  
Affinity Capture-MS Homo sapiens
153 SOX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 ZNF574  
Affinity Capture-MS Homo sapiens
155 DNAJC4  
Proximity Label-MS Homo sapiens
156 CLPP 8192
Proximity Label-MS Homo sapiens
157 DNAJC28  
Proximity Label-MS Homo sapiens
158 FN1 2335
Affinity Capture-MS Homo sapiens
159 ZNF707  
Affinity Capture-MS Homo sapiens
160 C8orf33 65265
Affinity Capture-MS Homo sapiens
161 C17orf80 55028
Proximity Label-MS Homo sapiens
162 FBXW11  
Affinity Capture-MS Homo sapiens
163 METTL17  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 AUH 549
Proximity Label-MS Homo sapiens
165 TP53 7157
Affinity Capture-MS Homo sapiens
166 TBRG4 9238
Proximity Label-MS Homo sapiens
167 MRPL11 65003
Proximity Label-MS Homo sapiens
168 DNAJC19 131118
Proximity Label-MS Homo sapiens
169 MCAT 27349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 MRPS2 51116
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 RPL6 6128
Affinity Capture-MS Homo sapiens
172 MTRF1L  
Proximity Label-MS Homo sapiens
173 ETV3  
Proximity Label-MS Homo sapiens
174 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
175 SOX15  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 ZNF746  
Affinity Capture-MS Homo sapiens
177 POLR1C 9533
Two-hybrid Homo sapiens
178 MRPS18C  
Affinity Capture-MS Homo sapiens
179 MRPS31  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
181 DNAJA3 9093
Proximity Label-MS Homo sapiens
182 SMURF1 57154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 ZBTB2 57621
Affinity Capture-MS Homo sapiens
185 COX8A  
Proximity Label-MS Homo sapiens
186 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 C21orf33  
Proximity Label-MS Homo sapiens
188 MRPS21  
Affinity Capture-MS Homo sapiens
189 SSBP1 6742
Proximity Label-MS Homo sapiens
190 TMEM70  
Proximity Label-MS Homo sapiens
191 UFL1 23376
Affinity Capture-MS Homo sapiens
192 FASTKD3  
Proximity Label-MS Homo sapiens
193 GID4  
Affinity Capture-MS Homo sapiens
194 NEIL1  
Affinity Capture-MS Homo sapiens
195 LONP1 9361
Proximity Label-MS Homo sapiens
196 MRPS18B 28973
Affinity Capture-MS Homo sapiens
197 GFM1 85476
Proximity Label-MS Homo sapiens
198 HNRNPL 3191
Affinity Capture-MS Homo sapiens
199 EIF4B 1975
Affinity Capture-MS Homo sapiens
200 TEFM  
Proximity Label-MS Homo sapiens
201 MRPS9 64965
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 C19orf52  
Proximity Label-MS Homo sapiens
203 MGME1  
Affinity Capture-MS Homo sapiens
204 AP4M1 9179
Affinity Capture-MS Homo sapiens
205 RPUSD3  
Proximity Label-MS Homo sapiens
206 HNRNPA1L2 144983
Affinity Capture-MS Homo sapiens
207 TRMT10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 MRPS16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 GRSF1 2926
Proximity Label-MS Homo sapiens
210 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
211 PPAN 56342
Affinity Capture-MS Homo sapiens
212 SMURF2 64750
Affinity Capture-MS Homo sapiens
213 ZNF331  
Affinity Capture-MS Homo sapiens
214 MRPS22 56945
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
215 SP7  
Proximity Label-MS Homo sapiens
216 STRBP 55342
Affinity Capture-MS Homo sapiens
217 DDX28  
Proximity Label-MS Homo sapiens
218 RPL17 6139
Affinity Capture-MS Homo sapiens
219 PSMD3 5709
Co-fractionation Homo sapiens
View the network image/svg+xml