Gene description for EIF4B
Gene name eukaryotic translation initiation factor 4B
Gene symbol EIF4B
Other names/aliases EIF-4B
PRO1843
Species Homo sapiens
 Database cross references - EIF4B
ExoCarta ExoCarta_1975
Vesiclepedia VP_1975
Entrez Gene 1975
HGNC 3285
MIM 603928
UniProt P23588  
 EIF4B identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for EIF4B
Molecular Function
    RNA binding GO:0003723 HDA
    translation initiation factor activity GO:0003743 IEA
    protein binding GO:0005515 IPI
    RNA strand annealing activity GO:0033592 IBA
    RNA strand-exchange activity GO:0034057 IBA
    ribosomal small subunit binding GO:0043024 IBA
Biological Process
    formation of translation preinitiation complex GO:0001731 IBA
    translational initiation GO:0006413 IEA
    regulation of translational initiation GO:0006446 TAS
    eukaryotic translation initiation factor 4F complex assembly GO:0097010 IBA
Subcellular Localization
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    eukaryotic translation initiation factor 4F complex GO:0016281 TAS
 Experiment description of studies that identified EIF4B in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
17
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
18
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
19
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for EIF4B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 EIF3A 8661
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
3 SLFN11 91607
Proximity Label-MS Homo sapiens
4 RPSAP58 388524
Affinity Capture-MS Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 TRAPPC8 22878
Affinity Capture-MS Homo sapiens
7 GEMIN5 25929
Co-fractionation Homo sapiens
8 PPP1CB 5500
Cross-Linking-MS (XL-MS) Homo sapiens
9 FAM98A 25940
Affinity Capture-MS Homo sapiens
10 POT1  
Two-hybrid Homo sapiens
11 CPOX 1371
Co-fractionation Homo sapiens
12 SNX1 6642
Co-fractionation Homo sapiens
13 EIF3C 8663
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
14 RBM12B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 EIF3K 27335
Affinity Capture-MS Homo sapiens
16 GJA1 2697
Affinity Capture-MS Homo sapiens
17 PBK  
Co-fractionation Homo sapiens
18 SSB 6741
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
19 YWHAE 7531
Affinity Capture-MS Homo sapiens
20 HSP90AA1 3320
Cross-Linking-MS (XL-MS) Homo sapiens
21 HNRNPDL 9987
Co-fractionation Homo sapiens
22 RPS4X 6191
Affinity Capture-MS Homo sapiens
23 ALB 213
Affinity Capture-MS Homo sapiens
24 PAK2 5062
Co-fractionation Homo sapiens
25 VPS35 55737
Co-fractionation Homo sapiens
26 TSG101 7251
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
27 DDX3Y 8653
Affinity Capture-MS Homo sapiens
28 CDC25B 994
Affinity Capture-MS Homo sapiens
29 CCT4 10575
Co-fractionation Homo sapiens
30 RPL14 9045
Affinity Capture-MS Homo sapiens
31 CSNK2A1 1457
Biochemical Activity Homo sapiens
32 EIF4A1 1973
Co-fractionation Homo sapiens
33 CCT6B 10693
Co-fractionation Homo sapiens
34 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
35 CFL1 1072
Co-fractionation Homo sapiens
36 ZBTB1  
Affinity Capture-MS Homo sapiens
37 HIST1H2AD 3013
Cross-Linking-MS (XL-MS) Homo sapiens
38 EIF3B 8662
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 HSPA5 3309
Co-fractionation Homo sapiens
40 GRB7 2886
Affinity Capture-MS Homo sapiens
41 KIAA1429 25962
Affinity Capture-MS Homo sapiens
42 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
43 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
44 RPS20 6224
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
45 RDX 5962
Co-fractionation Homo sapiens
46 CORO1B 57175
Co-fractionation Homo sapiens
47 LOC102724334 102724334
Cross-Linking-MS (XL-MS) Homo sapiens
48 IMPDH2 3615
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
49 DYRK1A 1859
Affinity Capture-MS Homo sapiens
50 OTUB1 55611
Co-fractionation Homo sapiens
51 RANBP10 57610
Affinity Capture-MS Homo sapiens
52 H1FX 8971
Cross-Linking-MS (XL-MS) Homo sapiens
53 TSNAX 7257
Co-fractionation Homo sapiens
54 NUP153 9972
Co-fractionation Homo sapiens
55 KIF5B 3799
Co-fractionation Homo sapiens
56 MRPS23 51649
Affinity Capture-MS Homo sapiens
57 OSBP 5007
Co-fractionation Homo sapiens
58 PLK4  
Affinity Capture-MS Homo sapiens
59 METAP2 10988
Affinity Capture-MS Homo sapiens
60 LASP1 3927
Co-fractionation Homo sapiens
61 AGO3  
Affinity Capture-MS Homo sapiens
62 Naa10  
Affinity Capture-MS Mus musculus
63 CAPZA1 829
Co-fractionation Homo sapiens
64 RPS8 6202
Affinity Capture-MS Homo sapiens
65 HIST1H2BN 8341
Cross-Linking-MS (XL-MS) Homo sapiens
66 NARS 4677
Co-fractionation Homo sapiens
67 PSME1 5720
Co-fractionation Homo sapiens
68 TINF2  
Two-hybrid Homo sapiens
69 BOD1L1 259282
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
70 GSPT1 2935
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
71 XPO7 23039
Co-fractionation Homo sapiens
72 EIF3E 3646
Affinity Capture-MS Homo sapiens
73 IKBKE 9641
Affinity Capture-MS Homo sapiens
74 DYNLL1 8655
Co-fractionation Homo sapiens
75 ALK 238
Affinity Capture-MS Homo sapiens
76 SNRPD3 6634
Affinity Capture-MS Homo sapiens
77 RPL29 6159
Co-fractionation Homo sapiens
78 ATG16L1 55054
Affinity Capture-MS Homo sapiens
79 Ccdc15  
Affinity Capture-MS Mus musculus
80 SFN 2810
Far Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
81 RPS9 6203
Affinity Capture-MS Homo sapiens
82 HSPA6 3310
Affinity Capture-MS Homo sapiens
83 SEC23A 10484
Co-fractionation Homo sapiens
84 SNX27 81609
Affinity Capture-MS Homo sapiens
85 SLC4A1AP  
Co-fractionation Homo sapiens
86 RBM42  
Affinity Capture-MS Homo sapiens
87 USP7 7874
Affinity Capture-MS Homo sapiens
88 TSN 7247
Co-fractionation Homo sapiens
89 RPS11 6205
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
90 CCT5 22948
Co-fractionation Homo sapiens
91 NIF3L1 60491
Affinity Capture-MS Homo sapiens
92 DENND1C  
Affinity Capture-MS Homo sapiens
93 RBM8A 9939
Affinity Capture-MS Homo sapiens
94 Tmed10 68581
Affinity Capture-MS Mus musculus
95 DYNC1H1 1778
Co-fractionation Homo sapiens
96 PRNP 5621
Affinity Capture-MS Homo sapiens
97 HIST3H2BB 128312
Cross-Linking-MS (XL-MS) Homo sapiens
98 SAMHD1 25939
Co-fractionation Homo sapiens
99 CCT2 10576
Co-fractionation Homo sapiens
100 RBMX 27316
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
101 Wiz  
Affinity Capture-MS Mus musculus
102 CHMP4C 92421
Affinity Capture-MS Homo sapiens
103 Pten  
Affinity Capture-MS Mus musculus
104 TOLLIP 54472
Proximity Label-MS Homo sapiens
105 PPP1CA 5499
Co-fractionation Homo sapiens
106 SRP9 6726
Affinity Capture-MS Homo sapiens
107 ATP5A1 498
Co-fractionation Homo sapiens
108 RPS19 6223
Affinity Capture-MS Homo sapiens
109 EIF4G1 1981
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
110 DDX39A 10212
Co-fractionation Homo sapiens
111 RPL9 6133
Affinity Capture-MS Homo sapiens
112 USP11 8237
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
113 CUL4B 8450
Co-fractionation Homo sapiens
114 PARK2  
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
115 KLC1 3831
Co-fractionation Homo sapiens
116 PHAX  
Co-fractionation Homo sapiens
117 RPS10 6204
Affinity Capture-MS Homo sapiens
118 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
119 CSTF2 1478
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
120 SRSF3 6428
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
121 MAPRE1 22919
Affinity Capture-MS Homo sapiens
122 PSMD14 10213
Affinity Capture-MS Homo sapiens
123 RCC2 55920
Co-fractionation Homo sapiens
124 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
125 RPL5 6125
Affinity Capture-MS Homo sapiens
126 PABPC1 26986
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
127 CDH1 999
Proximity Label-MS Homo sapiens
128 SNRPD1 6632
Affinity Capture-MS Homo sapiens
129 PSMD2 5708
Cross-Linking-MS (XL-MS) Homo sapiens
130 MYH9 4627
Co-fractionation Homo sapiens
131 VCP 7415
Affinity Capture-MS Homo sapiens
132 DDX5 1655
Co-fractionation Homo sapiens
133 NTRK1 4914
Affinity Capture-MS Homo sapiens
134 RPL31 6160
Affinity Capture-MS Homo sapiens
135 RPS7 6201
Affinity Capture-MS Homo sapiens
136 IFI16 3428
Affinity Capture-MS Homo sapiens
137 HIST2H2AA3 8337
Cross-Linking-MS (XL-MS) Homo sapiens
138 CMTR1 23070
Co-fractionation Homo sapiens
139 SRSF9 8683
Affinity Capture-MS Homo sapiens
140 RPL13A 23521
Cross-Linking-MS (XL-MS) Homo sapiens
141 MAEL  
Affinity Capture-MS Homo sapiens
142 CARM1 10498
Co-fractionation Homo sapiens
143 BICD2 23299
Proximity Label-MS Homo sapiens
144 YWHAQ 10971
Co-fractionation Homo sapiens
145 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
146 CTPS1 1503
Co-fractionation Homo sapiens
147 EIF4G2 1982
Co-fractionation Homo sapiens
148 RPS6 6194
Affinity Capture-MS Homo sapiens
149 MAGOH 4116
Affinity Capture-MS Homo sapiens
150 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
151 RPS16 6217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 RPS15A 6210
Affinity Capture-MS Homo sapiens
153 CEBPA  
Protein-peptide Homo sapiens
154 EIF3I 8668
Affinity Capture-MS Homo sapiens
155 CYLD  
Affinity Capture-MS Homo sapiens
156 DLEC1  
Affinity Capture-MS Homo sapiens
157 BZW1 9689
Co-fractionation Homo sapiens
158 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
159 ACD  
Two-hybrid Homo sapiens
160 LARP1 23367
Co-fractionation Homo sapiens
161 HEATR6  
Co-fractionation Homo sapiens
162 TRIM28 10155
Co-fractionation Homo sapiens
163 RTCB 51493
Affinity Capture-MS Homo sapiens
164 PHLPP1  
Proximity Label-MS Homo sapiens
165 GATAD2A 54815
Cross-Linking-MS (XL-MS) Homo sapiens
166 HNRNPD 3184
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
167 EIF3G 8666
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 GAN 8139
Affinity Capture-MS Homo sapiens
169 RNF40 9810
Co-fractionation Homo sapiens
170 HYOU1 10525
Co-fractionation Homo sapiens
171 RHOU 58480
Reconstituted Complex Homo sapiens
172 ANKRD53  
Affinity Capture-MS Homo sapiens
173 IPO5 3843
Co-fractionation Homo sapiens
174 AHCY 191
Co-fractionation Homo sapiens
175 TDRD5  
Affinity Capture-MS Homo sapiens
176 METTL14  
Affinity Capture-MS Homo sapiens
177 SF1 7536
Co-fractionation Homo sapiens
178 TMEM232  
Affinity Capture-MS Homo sapiens
179 XPO1 7514
Affinity Capture-MS Homo sapiens
180 GLMN 11146
Co-fractionation Homo sapiens
181 RC3H2  
Affinity Capture-MS Homo sapiens
182 USP9X 8239
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
183 CCT6A 908
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
184 SMAD3 4088
Reconstituted Complex Homo sapiens
185 EEF2 1938
Co-fractionation Homo sapiens
186 Smad3  
Affinity Capture-MS Mus musculus
187 PRKAR1A 5573
Co-fractionation Homo sapiens
188 Ttll12 223723
Affinity Capture-MS Mus musculus
189 LIG1 3978
Co-fractionation Homo sapiens
190 CUL3 8452
Affinity Capture-MS Homo sapiens
191 YWHAZ 7534
Co-fractionation Homo sapiens
192 TXNRD1 7296
Co-fractionation Homo sapiens
193 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
194 CCT8 10694
Co-fractionation Homo sapiens
195 RPL24 6152
Affinity Capture-MS Homo sapiens
196 HSPA8 3312
Affinity Capture-MS Homo sapiens
197 PRMT3 10196
Co-fractionation Homo sapiens
198 FBXO6 26270
Affinity Capture-MS Homo sapiens
199 RPS17 6218
Affinity Capture-MS Homo sapiens
200 KBTBD7  
Affinity Capture-MS Homo sapiens
201 LARS 51520
Co-fractionation Homo sapiens
202 UBR7  
Co-fractionation Homo sapiens
203 HIST1H2BO 8348
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
204 SSH3 54961
Co-fractionation Homo sapiens
205 Stk11  
Affinity Capture-MS Mus musculus
206 DOHH 83475
Co-fractionation Homo sapiens
207 CDON  
Affinity Capture-MS Homo sapiens
208 FASN 2194
Positive Genetic Homo sapiens
Co-fractionation Homo sapiens
209 RPA3 6119
Proximity Label-MS Homo sapiens
210 AGO4  
Affinity Capture-MS Homo sapiens
211 NAPA 8775
Co-fractionation Homo sapiens
212 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
213 PSPC1 55269
Affinity Capture-MS Homo sapiens
214 FLNB 2317
Co-fractionation Homo sapiens
215 DYNC1LI1 51143
Co-fractionation Homo sapiens
216 RPS13 6207
Affinity Capture-MS Homo sapiens
217 MCMBP 79892
Co-fractionation Homo sapiens
218 FAM208B 54906
Cross-Linking-MS (XL-MS) Homo sapiens
219 RPS14 6208
Affinity Capture-MS Homo sapiens
220 ACOX3 8310
Co-fractionation Homo sapiens
221 PRDM13 59336
Affinity Capture-MS Homo sapiens
222 HSPA1A 3303
Affinity Capture-MS Homo sapiens
223 RPL22 6146
Affinity Capture-MS Homo sapiens
224 ACAD9 28976
Co-fractionation Homo sapiens
225 GET4 51608
Co-fractionation Homo sapiens
226 CAPZA2 830
Co-fractionation Homo sapiens
227 RPL18 6141
Affinity Capture-MS Homo sapiens
228 PLS3 5358
Co-fractionation Homo sapiens
229 RPS18 6222
Affinity Capture-MS Homo sapiens
230 CTNNA1 1495
Co-fractionation Homo sapiens
231 HSPD1 3329
Co-fractionation Homo sapiens
232 DDX1 1653
Affinity Capture-MS Homo sapiens
233 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
234 FEZF2  
Affinity Capture-MS Homo sapiens
235 MGEA5 10724
Co-fractionation Homo sapiens
236 XRCC5 7520
Co-fractionation Homo sapiens
237 HUWE1 10075
Affinity Capture-MS Homo sapiens
238 EIF3D 8664
Affinity Capture-MS Homo sapiens
239 EIF3H 8667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 DSP 1832
Co-fractionation Homo sapiens
241 RRBP1 6238
Co-fractionation Homo sapiens
242 RPS3A 6189
Affinity Capture-MS Homo sapiens
243 AHSA1 10598
Affinity Capture-MS Homo sapiens
244 YBX1 4904
Co-fractionation Homo sapiens
245 NCOA5  
Affinity Capture-MS Homo sapiens
246 EIF3F 8665
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 ARRB2 409
Affinity Capture-MS Homo sapiens
248 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
249 FBXW11  
Affinity Capture-MS Homo sapiens
250 NUP107 57122
Co-fractionation Homo sapiens
251 ARPC5 10092
Affinity Capture-MS Homo sapiens
252 RPS25 6230
Affinity Capture-MS Homo sapiens
253 ERCC6L 54821
Affinity Capture-MS Homo sapiens
254 RPS3 6188
Affinity Capture-MS Homo sapiens
255 SEC23IP 11196
Co-fractionation Homo sapiens
256 TP53 7157
Affinity Capture-MS Homo sapiens
257 SMS 6611
Co-fractionation Homo sapiens
258 TTC4  
Co-fractionation Homo sapiens
259 RUVBL2 10856
Co-fractionation Homo sapiens
260 TNFAIP1 7126
Affinity Capture-MS Homo sapiens
261 SLK 9748
Co-fractionation Homo sapiens
262 DDX3X 1654
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 POLR1C 9533
Co-fractionation Homo sapiens
264 GRHPR 9380
Affinity Capture-MS Homo sapiens
265 HNRNPA2B1 3181
Co-fractionation Homo sapiens
266 RPS12 6206
Affinity Capture-MS Homo sapiens
267 SLC45A3  
Affinity Capture-MS Homo sapiens
268 SMURF1 57154
Affinity Capture-MS Homo sapiens
269 MAGEL2  
Proximity Label-MS Homo sapiens
270 RBM39 9584
Cross-Linking-MS (XL-MS) Homo sapiens
271 HSPB1 3315
Co-fractionation Homo sapiens
272 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
273 BAZ2A  
Affinity Capture-MS Homo sapiens
274 G3BP2 9908
Affinity Capture-MS Homo sapiens
275 EIF4A3 9775
Affinity Capture-MS Homo sapiens
276 GTF2I 2969
Co-fractionation Homo sapiens
277 CREB1  
Co-fractionation Homo sapiens
278 RPS5 6193
Affinity Capture-MS Homo sapiens
279 OTUD6B 51633
Affinity Capture-Western Homo sapiens
280 HNRNPK 3190
Co-fractionation Homo sapiens
281 CCT7 10574
Co-fractionation Homo sapiens
282 RAD50 10111
Co-fractionation Homo sapiens
283 RPS26 6231
Affinity Capture-MS Homo sapiens
284 UFL1 23376
Affinity Capture-MS Homo sapiens
285 SNRPN 6638
Affinity Capture-MS Homo sapiens
286 TBK1 29110
Affinity Capture-MS Homo sapiens
287 FGF11  
Affinity Capture-MS Homo sapiens
288 Crebbp  
Affinity Capture-MS Mus musculus
289 TERF1 7013
Two-hybrid Homo sapiens
290 MCM5 4174
Co-fractionation Homo sapiens
291 RPS24 6229
Affinity Capture-MS Homo sapiens
292 NCL 4691
Co-fractionation Homo sapiens
293 EIF3J 8669
Affinity Capture-MS Homo sapiens
294 RPS23 6228
Affinity Capture-MS Homo sapiens
295 EIF4B 1975
Far Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
296 ARRB1 408
Affinity Capture-MS Homo sapiens
297 KHSRP 8570
Co-fractionation Homo sapiens
298 PRKCA 5578
Co-fractionation Homo sapiens
299 PINK1  
Affinity Capture-MS Homo sapiens
300 DSG4 147409
Affinity Capture-MS Homo sapiens
301 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
302 USP48  
Co-fractionation Homo sapiens
303 METTL3  
Affinity Capture-MS Homo sapiens
304 C14orf166 51637
Affinity Capture-MS Homo sapiens
305 SERBP1 26135
Proximity Label-MS Homo sapiens
306 TXNIP 10628
Affinity Capture-MS Homo sapiens
307 RPL23A 6147
Affinity Capture-MS Homo sapiens
308 KRAS 3845
Negative Genetic Homo sapiens
309 HNRNPU 3192
Affinity Capture-MS Homo sapiens
310 EIF3M 10480
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
311 RNF113A 7737
Affinity Capture-MS Homo sapiens
312 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 WARS 7453
Co-fractionation Homo sapiens
314 PRMT1 3276
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 USP9Y 8287
Affinity Capture-MS Homo sapiens
316 ASB2  
Affinity Capture-MS Homo sapiens
317 EIF3L 51386
Affinity Capture-MS Homo sapiens
318 DYNC1LI2 1783
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here