Gene description for TRAPPC8
Gene name trafficking protein particle complex 8
Gene symbol TRAPPC8
Other names/aliases GSG1
HsT2706
KIAA1012
TRS85
Species Homo sapiens
 Database cross references - TRAPPC8
ExoCarta ExoCarta_22878
Entrez Gene 22878
HGNC 29169
MIM 614136
UniProt Q9Y2L5  
 TRAPPC8 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for TRAPPC8
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    peroxisome degradation GO:0030242 IBA
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    nucleophagy GO:0044804 IBA
    autophagosome assembly GO:0000045 IBA
    protein localization to pre-autophagosomal structure GO:0034497 IBA
    CVT pathway GO:0032258 IBA
Subcellular Localization
    pre-autophagosomal structure GO:0000407 IBA
    cytoplasmic vesicle GO:0031410 IBA
    TRAPPIII protein complex GO:1990072 IBA
 Experiment description of studies that identified TRAPPC8 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TRAPPC8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TRAPPC8 is involved
No pathways found





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