Gene description for TRAPPC9
Gene name trafficking protein particle complex 9
Gene symbol TRAPPC9
Other names/aliases IBP
IKBKBBP
MRT13
NIBP
T1
TRS120
Species Homo sapiens
 Database cross references - TRAPPC9
ExoCarta ExoCarta_83696
Vesiclepedia VP_83696
Entrez Gene 83696
HGNC 30832
MIM 611966
UniProt Q96Q05  
 TRAPPC9 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for TRAPPC9
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 NAS
    vesicle coating GO:0006901 NAS
    cerebral cortex development GO:0021987 IMP
    neuron differentiation GO:0030182 IEA
    vesicle tethering GO:0099022 NAS
Subcellular Localization
    cytoplasm GO:0005737 NAS
    endoplasmic reticulum GO:0005783 IEA
    trans-Golgi network GO:0005802 IBA
    cytosol GO:0005829 TAS
    TRAPP complex GO:0030008 IDA
    TRAPPII protein complex GO:1990071 NAS
 Experiment description of studies that identified TRAPPC9 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TRAPPC9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SART1 9092
Affinity Capture-MS Homo sapiens
2 TRAPPC3L  
Two-hybrid Homo sapiens
3 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
4 RUFY4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 SULT1A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PDLIM7 9260
Affinity Capture-MS Homo sapiens
7 NFATC3 4775
Proximity Label-MS Homo sapiens
8 NTRK1 4914
Affinity Capture-MS Homo sapiens
9 SLC31A1 1317
Affinity Capture-MS Homo sapiens
10 CRTAC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 LAMTOR1 55004
Proximity Label-MS Homo sapiens
12 TRAPPC5 126003
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 TRAPPC1 58485
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 TRAPPC10 7109
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
15 KIF14 9928
Affinity Capture-MS Homo sapiens
16 CABS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 KLK5 25818
Affinity Capture-MS Homo sapiens
18 ATG9A 79065
Proximity Label-MS Homo sapiens
19 RC3H2  
Affinity Capture-MS Homo sapiens
20 ZADH2 284273
Affinity Capture-MS Homo sapiens
21 ACAA1 30
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ODF3L2  
Affinity Capture-MS Homo sapiens
23 AMOTL2 51421
Affinity Capture-MS Homo sapiens
24 CRYAB 1410
Affinity Capture-MS Homo sapiens
25 TRAPPC8 22878
Two-hybrid Homo sapiens
26 MID1IP1  
Affinity Capture-MS Homo sapiens
27 GATA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 TRAPPC12 51112
Two-hybrid Homo sapiens
29 ISCA1  
Affinity Capture-MS Homo sapiens
30 NACC2  
Affinity Capture-MS Homo sapiens
31 ADI1 55256
Affinity Capture-MS Homo sapiens
32 RAB43 339122
Affinity Capture-MS Homo sapiens
33 TRAPPC2B  
Affinity Capture-MS Homo sapiens
34 APP 351
Reconstituted Complex Homo sapiens
35 NXF1 10482
Affinity Capture-RNA Homo sapiens
36 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 STMN4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 Ezr 22350
Affinity Capture-MS Mus musculus
39 FAM19A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 RAB30 27314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 TRAPPC3 27095
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
42 BTBD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 MOV10 4343
Affinity Capture-RNA Homo sapiens
44 MB21D2  
Affinity Capture-MS Homo sapiens
45 TRAPPC4 51399
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
46 TBC1D14 57533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 YWHAH 7533
Affinity Capture-MS Homo sapiens
48 RAB11A 8766
Proximity Label-MS Homo sapiens
49 KCNQ3  
Affinity Capture-MS Homo sapiens
50 TRAPPC2L 51693
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 RAB3IP  
Affinity Capture-MS Homo sapiens
52 GLB1 2720
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 GATSL2  
Co-fractionation Homo sapiens
54 CGA  
Affinity Capture-MS Homo sapiens
55 TMEM102  
Affinity Capture-MS Homo sapiens
56 RAB3IL1 5866
Affinity Capture-MS Homo sapiens
57 BHLHA15  
Affinity Capture-MS Homo sapiens
58 KANK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 APBA1  
Affinity Capture-MS Homo sapiens
60 BCL2L14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 HOXB6 3216
Affinity Capture-MS Homo sapiens
62 CNN2 1265
Affinity Capture-MS Homo sapiens
63 MTL5  
Affinity Capture-MS Homo sapiens
64 IKBKB 3551
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
65 KCTD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 NOTCH1 4851
Affinity Capture-MS Homo sapiens
67 GRAMD1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 STX6 10228
Proximity Label-MS Homo sapiens
69 HUNK  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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