Gene description for TECPR1
Gene name tectonin beta-propeller repeat containing 1
Gene symbol TECPR1
Other names/aliases -
Species Homo sapiens
 Database cross references - TECPR1
ExoCarta ExoCarta_25851
Vesiclepedia VP_25851
Entrez Gene 25851
HGNC 22214
MIM 614781
UniProt Q7Z6L1  
 TECPR1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TECPR1
Molecular Function
    protein binding GO:0005515 IPI
    phosphatidylinositol-3-phosphate binding GO:0032266 IBA
    phosphatidylinositol-3-phosphate binding GO:0032266 IDA
Biological Process
    autophagy GO:0006914 IDA
    macroautophagy GO:0016236 IMP
    autophagosome maturation GO:0097352 IBA
    autophagosome maturation GO:0097352 IMP
    regulation of autophagosome maturation GO:1901096 IMP
Subcellular Localization
    autophagosome membrane GO:0000421 IBA
    autophagosome membrane GO:0000421 IDA
    nucleoplasm GO:0005654 IDA
    lysosomal membrane GO:0005765 IBA
    lysosomal membrane GO:0005765 IDA
    cytoplasmic vesicle GO:0031410 IEA
    protein-containing complex GO:0032991 NAS
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified TECPR1 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TECPR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRAPPC8 22878
Affinity Capture-MS Homo sapiens
2 ATG12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 TRAPPC11 60684
Affinity Capture-MS Homo sapiens
4 PLOD3 8985
Affinity Capture-MS Homo sapiens
5 COL18A1 80781
Affinity Capture-MS Homo sapiens
6 MCMBP 79892
Affinity Capture-MS Homo sapiens
7 ATG5 9474
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
8 ATG3 64422
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TRAPPC12 51112
Affinity Capture-MS Homo sapiens
10 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which TECPR1 is involved
No pathways found





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