Gene description for MCMBP
Gene name minichromosome maintenance complex binding protein
Gene symbol MCMBP
Other names/aliases C10orf119
MCM-BP
Species Homo sapiens
 Database cross references - MCMBP
ExoCarta ExoCarta_79892
Entrez Gene 79892
HGNC 25782
MIM 610909
UniProt Q9BTE3  
 MCMBP identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for MCMBP
Molecular Function
    protein binding GO:0005515 IPI
    chromatin binding GO:0003682 IDA
Biological Process
    sister chromatid cohesion GO:0007062 IMP
    cell division GO:0051301 IEA
    mitotic nuclear division GO:0007067 IEA
    DNA-dependent DNA replication GO:0006261 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    MCM complex GO:0042555 IDA
    plasma membrane GO:0005886 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified MCMBP in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for MCMBP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DDIT3 1649
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MCMBP is involved
No pathways found





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