Gene description for Mcm3
Gene name minichromosome maintenance deficient 3 (S. cerevisiae)
Gene symbol Mcm3
Other names/aliases AL033361
C80350
Mcmd
P1
p1.m
Species Mus musculus
 Database cross references - Mcm3
ExoCarta ExoCarta_17215
Entrez Gene 17215
UniProt P25206  
 Mcm3 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Mcm3
Molecular Function
    DNA binding GO:0003677 IEA
    DNA helicase activity GO:0003678 IEA
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
    nucleotide binding GO:0000166 IEA
    helicase activity GO:0004386 IEA
Biological Process
    cell cycle GO:0007049 IEA
    DNA replication initiation GO:0006270 IEA
    DNA replication GO:0006260 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    centrosome GO:0005813 ISO
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    MCM complex GO:0042555 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Mcm3 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mcm3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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