Gene description for STAT5B
Gene name	signal transducer and activator of transcription 5B
Gene symbol	STAT5B
Other names/aliases	STAT5
Species	Homo sapiens
Database cross references - STAT5B
ExoCarta	ExoCarta_6777
Entrez Gene	6777
HGNC	11367
MIM	604260
UniProt	P51692
STAT5B identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for STAT5B

Molecular Function     glucocorticoid receptor binding GO:0035259 IPI     protein binding GO:0005515 IPI     signal transducer activity GO:0004871 IEA     protein dimerization activity GO:0046983 ISS     protein phosphatase binding GO:0019903 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 IEA     chromatin binding GO:0003682 ISS     RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IEA     double-stranded DNA binding GO:0003690 IEA Biological Process     cellular response to hormone stimulus GO:0032870 IDA     T cell homeostasis GO:0043029 IEA     prolactin signaling pathway GO:0038161 ISS     positive regulation of cellular component movement GO:0051272 IEA     response to interleukin-2 GO:0070669 IEA     positive regulation of gamma-delta T cell differentiation GO:0045588 IEA     fatty acid metabolic process GO:0006631 ISS     positive regulation of B cell differentiation GO:0045579 IEA     regulation of steroid metabolic process GO:0019218 IEA     cellular response to epidermal growth factor stimulus GO:0071364 ISS     positive regulation of smooth muscle cell proliferation GO:0048661 IEA     response to lipopolysaccharide GO:0032496 IEA     oxaloacetate metabolic process GO:0006107 ISS     Peyer's patch development GO:0048541 IEA     succinate metabolic process GO:0006105 ISS     2-oxoglutarate metabolic process GO:0006103 ISS     positive regulation of interleukin-2 biosynthetic process GO:0045086 IEA     development of secondary male sexual characteristics GO:0046544 IEA     valine metabolic process GO:0006573 ISS     taurine metabolic process GO:0019530 ISS     isoleucine metabolic process GO:0006549 ISS     JAK-STAT cascade GO:0007259 TAS     creatinine metabolic process GO:0046449 ISS     response to hypoxia GO:0001666 IEA     regulation of transcription from RNA polymerase II promoter GO:0006357 TAS     response to interleukin-4 GO:0070670 IEA     positive regulation of activated T cell proliferation GO:0042104 IEA     female pregnancy GO:0007565 IEA     positive regulation of inflammatory response GO:0050729 IEA     T cell differentiation in thymus GO:0033077 IEA     lactation GO:0007595 IEA     allantoin metabolic process GO:0000255 ISS     response to interleukin-15 GO:0070672 IEA     regulation of multicellular organism growth GO:0040014 ISS     liver development GO:0001889 IEA     acute-phase response GO:0006953 IEA     positive regulation of natural killer cell proliferation GO:0032819 IEA     development of secondary female sexual characteristics GO:0046543 IEA     cellular response to growth factor stimulus GO:0071363 ISS     negative regulation of erythrocyte differentiation GO:0045647 IEA     positive regulation of natural killer cell differentiation GO:0032825 IEA     response to estradiol GO:0032355 IDA     positive regulation of multicellular organism growth GO:0040018 IEA     response to ethanol GO:0045471 IEA     JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 TAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS     negative regulation of apoptotic process GO:0043066 IEA     lipid storage GO:0019915 IEA     citrate metabolic process GO:0006101 ISS     positive regulation of natural killer cell mediated cytotoxicity GO:0045954 IEA     transcription from RNA polymerase II promoter GO:0006366 IEA     progesterone metabolic process GO:0042448 IEA     positive regulation of mitotic cell cycle GO:0045931 IEA     regulation of epithelial cell differentiation GO:0030856 IEA     luteinization GO:0001553 IEA     creatine metabolic process GO:0006600 ISS     natural killer cell differentiation GO:0001779 IEA Subcellular Localization     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 ISS     cytosol GO:0005829 TAS     cytoplasm GO:0005737 ISS