Gene description for TPM3
Gene name tropomyosin 3
Gene symbol TPM3
Other names/aliases CAPM1
CFTD
HEL-189
HEL-S-82p
NEM1
OK/SW-cl.5
TM-5
TM3
TM30
TM30nm
TM5
TPMsk3
TRK
hscp30
Species Homo sapiens
 Database cross references - TPM3
ExoCarta ExoCarta_7170
Vesiclepedia VP_7170
Entrez Gene 7170
HGNC 12012
MIM 191030
UniProt P06753  
 TPM3 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for TPM3
Molecular Function
    protein binding GO:0005515 IPI
    actin filament binding GO:0051015 IBA
Biological Process
    muscle contraction GO:0006936 IBA
    actin filament organization GO:0007015 IBA
Subcellular Localization
    stress fiber GO:0001725 IDA
    mitochondrion GO:0005739 HTP
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoskeleton GO:0005856 NAS
    cytoskeleton GO:0005856 TAS
    muscle thin filament tropomyosin GO:0005862 TAS
    actin filament GO:0005884 IBA
    actin cytoskeleton GO:0015629 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified TPM3 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
13
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
14
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
15
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
16
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
17
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
18
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
27
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
33
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
34
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TPM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 PSMA6 5687
Co-fractionation Homo sapiens
3 COX5A 9377
Co-fractionation Homo sapiens
4 MCM3 4172
Co-fractionation Homo sapiens
5 RBMXL1  
Affinity Capture-MS Homo sapiens
6 HDAC4  
Affinity Capture-MS Homo sapiens
7 NUF2  
Affinity Capture-MS Homo sapiens
8 INSIG1  
Affinity Capture-MS Homo sapiens
9 PPP1CB 5500
Affinity Capture-MS Homo sapiens
10 MTCH1 23787
Co-fractionation Homo sapiens
11 PTMS 5763
Affinity Capture-MS Homo sapiens
12 BLOC1S6  
Two-hybrid Homo sapiens
13 Tpm1 22003
Affinity Capture-MS Mus musculus
14 PAXIP1  
Affinity Capture-MS Homo sapiens
15 STAT5B 6777
Affinity Capture-MS Homo sapiens
16 ARHGAP39  
Affinity Capture-MS Homo sapiens
17 MARCKS 4082
Affinity Capture-MS Homo sapiens
18 KIF5B 3799
Affinity Capture-MS Homo sapiens
19 PRPF8 10594
Affinity Capture-MS Homo sapiens
20 KLF9 687
Affinity Capture-MS Homo sapiens
21 KIFC3 3801
Two-hybrid Homo sapiens
22 MCC 4163
Affinity Capture-MS Homo sapiens
23 TPM2 7169
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
24 SP1  
Affinity Capture-MS Homo sapiens
25 GLB1 2720
Cross-Linking-MS (XL-MS) Homo sapiens
26 Calml3  
Affinity Capture-MS Mus musculus
27 BRCA1 672
Affinity Capture-MS Homo sapiens
28 SH3GLB2 56904
Co-fractionation Homo sapiens
29 DTNA  
Affinity Capture-MS Homo sapiens
30 JUND 3727
Affinity Capture-MS Homo sapiens
31 APOE 348
Affinity Capture-MS Homo sapiens
32 CALCOCO1 57658
Affinity Capture-MS Homo sapiens
33 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
34 MYO5C 55930
Affinity Capture-MS Homo sapiens
35 AAR2 25980
Affinity Capture-MS Homo sapiens
36 FKBP4 2288
Co-fractionation Homo sapiens
37 Actb 11461
Affinity Capture-MS Mus musculus
38 SYDE2  
Affinity Capture-MS Homo sapiens
39 PARK7 11315
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ISG15 9636
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
41 PBX3  
Two-hybrid Homo sapiens
42 SNAPIN 23557
Two-hybrid Homo sapiens
43 HSF2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 TGM2 7052
Co-fractionation Homo sapiens
45 PPP1CC 5501
Affinity Capture-MS Homo sapiens
46 SEPT9 10801
Co-fractionation Homo sapiens
47 RNH1 6050
Co-fractionation Homo sapiens
48 WTAP 9589
Affinity Capture-MS Homo sapiens
49 IMP3 55272
Affinity Capture-MS Homo sapiens
50 RPL4 6124
Cross-Linking-MS (XL-MS) Homo sapiens
51 JUNB  
Affinity Capture-MS Homo sapiens
52 NDE1 54820
Affinity Capture-MS Homo sapiens
53 Ophn1  
Affinity Capture-MS Mus musculus
54 B3GNT2 10678
Affinity Capture-MS Homo sapiens
55 WASH3P  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
56 CDC123 8872
Co-fractionation Homo sapiens
57 ATP1A3 478
Cross-Linking-MS (XL-MS) Homo sapiens
58 MCM2 4171
Affinity Capture-MS Homo sapiens
59 CKMT1A 548596
Co-fractionation Homo sapiens
60 PRMT5 10419
Co-fractionation Homo sapiens
61 SPAG9 9043
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 FBXW7  
Affinity Capture-MS Homo sapiens
63 IQGAP1 8826
Affinity Capture-MS Homo sapiens
64 MDC1  
Affinity Capture-MS Homo sapiens
65 HSPH1 10808
Co-fractionation Homo sapiens
66 ADD1 118
Affinity Capture-MS Homo sapiens
67 OIP5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
68 IFIT3 3437
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
69 OBSL1 23363
Affinity Capture-MS Homo sapiens
70 SF3A2 8175
Co-fractionation Homo sapiens
71 MAGED2 10916
Co-fractionation Homo sapiens
72 CCDC6 8030
Affinity Capture-MS Homo sapiens
73 WASH1 100287171
Two-hybrid Homo sapiens
74 LURAP1  
Two-hybrid Homo sapiens
75 PSMD2 5708
Co-fractionation Homo sapiens
76 TRIM26 7726
Affinity Capture-MS Homo sapiens
77 FBXO5  
Two-hybrid Homo sapiens
78 PHB 5245
Cross-Linking-MS (XL-MS) Homo sapiens
79 GOLGA4  
Co-fractionation Homo sapiens
80 ACSL1 2180
Co-fractionation Homo sapiens
81 CALR 811
Affinity Capture-MS Homo sapiens
82 YWHAG 7532
Co-fractionation Homo sapiens
83 PPP6R3 55291
Co-fractionation Homo sapiens
84 MYCN  
Affinity Capture-MS Homo sapiens
85 TLK1  
Two-hybrid Homo sapiens
86 THOC1 9984
Co-fractionation Homo sapiens
87 SMARCA2 6595
Affinity Capture-MS Homo sapiens
88 NEDD4 4734
Affinity Capture-MS Homo sapiens
89 SOD1 6647
Affinity Capture-MS Homo sapiens
90 RLIM 51132
Affinity Capture-MS Homo sapiens
91 DVL2 1856
Two-hybrid Homo sapiens
92 RBM8A 9939
Affinity Capture-MS Homo sapiens
93 KIF14 9928
Affinity Capture-MS Homo sapiens
94 THAP7  
Two-hybrid Homo sapiens
95 CCDC102A 92922
Affinity Capture-MS Homo sapiens
96 C1orf216  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
97 OSTF1 26578
Co-fractionation Homo sapiens
98 INSIG2  
Affinity Capture-MS Homo sapiens
99 PRMT1 3276
Affinity Capture-MS Homo sapiens
100 UFL1 23376
Affinity Capture-MS Homo sapiens
101 GATA4  
Affinity Capture-MS Homo sapiens
102 TAF6 6878
Co-fractionation Homo sapiens
103 MYO18A 399687
Affinity Capture-MS Homo sapiens
104 POLD1 5424
Affinity Capture-MS Homo sapiens
105 FOXC1  
Affinity Capture-MS Homo sapiens
106 RIN3  
Affinity Capture-MS Homo sapiens
107 IKBIP 121457
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
108 ANTXR1 84168
Affinity Capture-MS Homo sapiens
109 PARK2  
Affinity Capture-MS Homo sapiens
110 FGA 2243
Two-hybrid Homo sapiens
111 CCAR2 57805
Co-fractionation Homo sapiens
112 DCTN5 84516
Co-fractionation Homo sapiens
113 METTL2B 55798
Affinity Capture-MS Homo sapiens
114 PSMC6 5706
Co-fractionation Homo sapiens
115 BRD3 8019
Cross-Linking-MS (XL-MS) Homo sapiens
116 PSMD13 5719
Co-fractionation Homo sapiens
117 EXOC4 60412
Affinity Capture-MS Homo sapiens
118 TRIM24  
Affinity Capture-MS Homo sapiens
119 FAM9C  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
120 DAPK1 1612
Affinity Capture-MS Homo sapiens
121 TNPO2 30000
Co-fractionation Homo sapiens
122 BTF3 689
Affinity Capture-MS Homo sapiens
123 MYH9 4627
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
124 ACTN4 81
Co-fractionation Homo sapiens
125 NTRK1 4914
Affinity Capture-MS Homo sapiens
126 PSMC5 5705
Co-fractionation Homo sapiens
127 ARHGAP11A  
Affinity Capture-MS Homo sapiens
128 U2AF2 11338
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
129 RAD18  
Affinity Capture-MS Homo sapiens
130 SUMO2 6613
Affinity Capture-MS Homo sapiens
131 CYC1 1537
Co-fractionation Homo sapiens
132 CAP1 10487
Co-fractionation Homo sapiens
133 CCDC101  
Affinity Capture-MS Homo sapiens
134 PSMC2 5701
Co-fractionation Homo sapiens
135 CCDC102B  
Two-hybrid Homo sapiens
136 NELFE 7936
Affinity Capture-MS Homo sapiens
137 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
138 PEBP1 5037
Affinity Capture-MS Homo sapiens
139 CAPZB 832
Affinity Capture-MS Homo sapiens
140 RAD21 5885
Affinity Capture-MS Homo sapiens
141 AHCYL1 10768
Co-fractionation Homo sapiens
142 CKMT1B 1159
Co-fractionation Homo sapiens
143 COX4I1 1327
Co-fractionation Homo sapiens
144 EIF4A2 1974
Affinity Capture-MS Homo sapiens
145 HDDC3  
Two-hybrid Homo sapiens
146 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
148 MYH7B  
Co-fractionation Homo sapiens
149 ACTN1 87
Co-fractionation Homo sapiens
150 TMPO 7112
Affinity Capture-MS Homo sapiens
151 CCDC114  
Two-hybrid Homo sapiens
152 HSF1  
Affinity Capture-MS Homo sapiens
153 Myh9 17886
Affinity Capture-MS Mus musculus
154 NKX2-5  
Affinity Capture-MS Homo sapiens
155 METTL14  
Affinity Capture-MS Homo sapiens
156 SYCE1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
157 NDUFB10 4716
Co-fractionation Homo sapiens
158 ECD  
Affinity Capture-MS Homo sapiens
159 KIF20A 10112
Affinity Capture-MS Homo sapiens
160 USP15 9958
Co-fractionation Homo sapiens
161 MAGEA11  
Two-hybrid Homo sapiens
162 ECT2 1894
Affinity Capture-MS Homo sapiens
163 MAD1L1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
164 LCA5L  
Two-hybrid Homo sapiens
165 UQCRC2 7385
Co-fractionation Homo sapiens
166 CTNNB1 1499
Affinity Capture-MS Homo sapiens
167 CD274 29126
Affinity Capture-MS Homo sapiens
168 Itga5 16402
Affinity Capture-MS Mus musculus
169 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 ATP5F1 515
Co-fractionation Homo sapiens
171 PSMA2 5683
Co-fractionation Homo sapiens
172 EGFR 1956
Affinity Capture-MS Homo sapiens
173 MYO19  
Affinity Capture-MS Homo sapiens
174 HOOK3 84376
Proximity Label-MS Homo sapiens
175 TFPT  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
176 TSSC4  
Affinity Capture-MS Homo sapiens
177 NDEL1 81565
Affinity Capture-MS Homo sapiens
178 HOMER1  
Affinity Capture-MS Homo sapiens
179 TP73  
Affinity Capture-Western Homo sapiens
180 CALM1 801
Affinity Capture-MS Homo sapiens
181 TBCD 6904
Co-fractionation Homo sapiens
182 FN1 2335
Affinity Capture-MS Homo sapiens
183 NXF1 10482
Affinity Capture-RNA Homo sapiens
184 AURKB 9212
Affinity Capture-MS Homo sapiens
185 JUN 3725
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 CDK2 1017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 ZIC3  
Affinity Capture-MS Homo sapiens
188 TPM1 7168
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
189 HOMER2  
Affinity Capture-MS Homo sapiens
190 FOS 2353
Proximity Label-MS Homo sapiens
191 MYC  
Affinity Capture-MS Homo sapiens
192 Mis12  
Affinity Capture-MS Mus musculus
193 TPM3P9  
Affinity Capture-MS Homo sapiens
194 TRIM27  
Two-hybrid Homo sapiens
195 KLF10  
Affinity Capture-MS Homo sapiens
196 OPA1 4976
Proximity Label-MS Homo sapiens
197 ACTN2 88
Co-fractionation Homo sapiens
198 MAP4 4134
Co-fractionation Homo sapiens
199 STMN1 3925
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
200 MFN2 9927
Proximity Label-MS Homo sapiens
201 RNF2  
Affinity Capture-MS Homo sapiens
202 CROCC 9696
Affinity Capture-MS Homo sapiens
203 VDAC1 7416
Affinity Capture-MS Homo sapiens
204 PGAM1 5223
Affinity Capture-MS Homo sapiens
205 RCOR3  
Affinity Capture-MS Homo sapiens
206 HSPA9 3313
Co-fractionation Homo sapiens
207 WIBG 84305
Cross-Linking-MS (XL-MS) Homo sapiens
208 TPM4 7171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
209 MGEA5 10724
Co-fractionation Homo sapiens
210 TPM3 7170
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
211 TNNT1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
212 ACTR1A 10121
Cross-Linking-MS (XL-MS) Homo sapiens
213 LARS 51520
Affinity Capture-MS Homo sapiens
214 NES 10763
Affinity Capture-MS Homo sapiens
215 KCNE1  
Two-hybrid Homo sapiens
216 TRIP6 7205
Two-hybrid Homo sapiens
217 LAMB1 3912
Cross-Linking-MS (XL-MS) Homo sapiens
218 PDLIM7 9260
Affinity Capture-MS Homo sapiens
219 NUP54 53371
Two-hybrid Homo sapiens
220 HSF4  
Two-hybrid Homo sapiens
221 FASN 2194
Co-fractionation Homo sapiens
222 EAPP  
Affinity Capture-MS Homo sapiens
223 PSMD1 5707
Co-fractionation Homo sapiens
224 GEMIN5 25929
Co-fractionation Homo sapiens
225 LRPPRC 10128
Co-fractionation Homo sapiens
226 THAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
227 FKBP3 2287
Affinity Capture-MS Homo sapiens
228 SEC23IP 11196
Co-fractionation Homo sapiens
229 TP53 7157
Affinity Capture-MS Homo sapiens
230 TRIM33 51592
Affinity Capture-MS Homo sapiens
231 CCHCR1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
232 VPS52 6293
Two-hybrid Homo sapiens
233 PDIA4 9601
Affinity Capture-MS Homo sapiens
234 CCDC146  
Two-hybrid Homo sapiens
235 PHLDB3  
Two-hybrid Homo sapiens
236 TSKS  
Two-hybrid Homo sapiens
237 KLF3  
Affinity Capture-MS Homo sapiens
238 PDHA1 5160
Affinity Capture-MS Homo sapiens
239 PSMB7 5695
Co-fractionation Homo sapiens
240 CAPZA2 830
Affinity Capture-MS Homo sapiens
241 HSPB1 3315
Co-fractionation Homo sapiens
242 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
243 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
244 TKT 7086
Affinity Capture-MS Homo sapiens
245 RNF20 56254
Affinity Capture-MS Homo sapiens
246 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
247 SHMT2 6472
Affinity Capture-RNA Homo sapiens
248 FKBP5 2289
Co-fractionation Homo sapiens
249 DDX58 23586
Affinity Capture-RNA Homo sapiens
250 Myh10 77579
Affinity Capture-MS Mus musculus
251 TRAP1 10131
Two-hybrid Homo sapiens
252 RCOR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
253 CHRM3 1131
Two-hybrid Homo sapiens
254 WDR77 79084
Co-fractionation Homo sapiens
255 KDM1A 23028
Affinity Capture-MS Homo sapiens
256 NEK2  
Two-hybrid Homo sapiens
257 MOV10 4343
Affinity Capture-RNA Homo sapiens
258 RPL27A 6157
Cross-Linking-MS (XL-MS) Homo sapiens
259 LRRK2 120892
Affinity Capture-MS Homo sapiens
260 RXRA 6256
Affinity Capture-MS Homo sapiens
261 ATP1A1 476
Co-fractionation Homo sapiens
262 PRDX1 5052
Co-fractionation Homo sapiens
263 CIT 11113
Affinity Capture-MS Homo sapiens
264 KXD1 79036
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
265 KYNU  
Co-fractionation Homo sapiens
266 CEP78 84131
Affinity Capture-MS Homo sapiens
267 CUL7 9820
Affinity Capture-MS Homo sapiens
268 AR 367
Affinity Capture-MS Homo sapiens
269 CCDC96  
Affinity Capture-MS Homo sapiens
270 PPP2R1A 5518
Co-fractionation Homo sapiens
271 PTRF 284119
Affinity Capture-MS Homo sapiens
272 HOOK2  
Two-hybrid Homo sapiens
273 Tpm4  
Affinity Capture-MS Mus musculus
274 HSPA8 3312
Co-fractionation Homo sapiens
275 TNNI1 7135
Two-hybrid Homo sapiens
276 CKB 1152
Co-fractionation Homo sapiens
277 PSMD3 5709
Co-fractionation Homo sapiens
278 PHF21A  
Affinity Capture-MS Homo sapiens
279 PRKCDBP 112464
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here