Gene description for MARCKS
Gene name myristoylated alanine-rich protein kinase C substrate
Gene symbol MARCKS
Other names/aliases 80K-L
MACS
PKCSL
PRKCSL
Species Homo sapiens
 Database cross references - MARCKS
ExoCarta ExoCarta_4082
Vesiclepedia VP_4082
Entrez Gene 4082
HGNC 6759
MIM 177061
UniProt P29966  
 MARCKS identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for MARCKS
Molecular Function
    protein kinase C binding GO:0005080 IEA
    calmodulin binding GO:0005516 IEA
    identical protein binding GO:0042802 IEA
    actin filament binding GO:0051015 IBA
Biological Process
    apoptotic process GO:0006915 IEA
    mitochondrion organization GO:0007005 IEA
    actin filament organization GO:0007015 IBA
    central nervous system development GO:0007417 IBA
    neural tube development GO:0021915 IEA
    neurogenesis GO:0022008 IEA
    response to endoplasmic reticulum stress GO:0034976 IEA
    actin filament bundle assembly GO:0051017 IEA
    actin crosslink formation GO:0051764 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    centrosome GO:0005813 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    focal adhesion GO:0005925 HDA
    cell cortex GO:0005938 IEA
    actin cytoskeleton GO:0015629 TAS
    actin filament bundle GO:0032432 IBA
    germinal vesicle GO:0042585 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified MARCKS in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
18
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
26
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
40
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
53
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
54
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
55
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MARCKS
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 ARHGAP1 392
Proximity Label-MS Homo sapiens
4 WDR6 11180
Proximity Label-MS Homo sapiens
5 UTRN 7402
Proximity Label-MS Homo sapiens
6 PTMS 5763
Affinity Capture-MS Homo sapiens
7 LLGL1 3996
Proximity Label-MS Homo sapiens
8 PKP2 5318
Proximity Label-MS Homo sapiens
9 JPH1 56704
Proximity Label-MS Homo sapiens
10 EBNA-LP  
Affinity Capture-MS
11 SLC2A1 6513
Proximity Label-MS Homo sapiens
12 RRAGD 58528
Proximity Label-MS Homo sapiens
13 MAP4K4 9448
Proximity Label-MS Homo sapiens
14 VPS13C 54832
Proximity Label-MS Homo sapiens
15 PARK7 11315
Affinity Capture-MS Homo sapiens
16 SEPT2 4735
Proximity Label-MS Homo sapiens
17 SEPT9 10801
Proximity Label-MS Homo sapiens
18 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
19 ABLIM1 3983
Proximity Label-MS Homo sapiens
20 NDRG1 10397
Proximity Label-MS Homo sapiens
21 SMPD4 55627
Proximity Label-MS Homo sapiens
22 UNC5B 219699
Proximity Label-MS Homo sapiens
23 STT3A 3703
Proximity Label-MS Homo sapiens
24 ABCD3 5825
Proximity Label-MS Homo sapiens
25 RASAL2 9462
Proximity Label-MS Homo sapiens
26 RPS9 6203
Proximity Label-MS Homo sapiens
27 CD99 4267
Proximity Label-MS Homo sapiens
28 MARCKSL1 65108
Proximity Label-MS Homo sapiens
29 BET1 10282
Proximity Label-MS Homo sapiens
30 MECP2 4204
Affinity Capture-MS Homo sapiens
31 NMT1 4836
Proximity Label-MS Homo sapiens
32 SLC12A7 10723
Proximity Label-MS Homo sapiens
33 SOD1 6647
Affinity Capture-MS Homo sapiens
34 STX12 23673
Proximity Label-MS Homo sapiens
35 TMEM87A 25963
Proximity Label-MS Homo sapiens
36 EXOC3 11336
Proximity Label-MS Homo sapiens
37 NOTCH2 4853
Proximity Label-MS Homo sapiens
38 CAMLG 819
Proximity Label-MS Homo sapiens
39 ZYX 7791
Proximity Label-MS Homo sapiens
40 SNAP47 116841
Proximity Label-MS Homo sapiens
41 SRPRB 58477
Proximity Label-MS Homo sapiens
42 PLD1 5337
Proximity Label-MS Homo sapiens
43 MCAM 4162
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
44 EFR3B  
Proximity Label-MS Homo sapiens
45 PDXDC1 23042
Proximity Label-MS Homo sapiens
46 AKAP1 8165
Proximity Label-MS Homo sapiens
47 RPL18A 6142
Proximity Label-MS Homo sapiens
48 CDH1 999
Proximity Label-MS Homo sapiens
49 CLCC1 23155
Proximity Label-MS Homo sapiens
50 GORASP2 26003
Proximity Label-MS Homo sapiens
51 Mapk13  
Affinity Capture-MS Mus musculus
52 MPP7 143098
Proximity Label-MS Homo sapiens
53 DDX39B 7919
Affinity Capture-MS Homo sapiens
54 FLOT2 2319
Proximity Label-MS Homo sapiens
55 PICALM 8301
Proximity Label-MS Homo sapiens
56 SPRY4 81848
Proximity Label-MS Homo sapiens
57 CISD1 55847
Proximity Label-MS Homo sapiens
58 PALM2  
Proximity Label-MS Homo sapiens
59 EPB41L1 2036
Proximity Label-MS Homo sapiens
60 ANO6 196527
Proximity Label-MS Homo sapiens
61 RHOU 58480
Reconstituted Complex Homo sapiens
62 FAM83B  
Proximity Label-MS Homo sapiens
63 FAM129B 64855
Proximity Label-MS Homo sapiens
64 AGPAT1 10554
Proximity Label-MS Homo sapiens
65 AHCYL1 10768
Proximity Label-MS Homo sapiens
66 DHCR7 1717
Proximity Label-MS Homo sapiens
67 CDCA3 83461
Proximity Label-MS Homo sapiens
68 SCAMP1 9522
Proximity Label-MS Homo sapiens
69 ERBB2IP 55914
Proximity Label-MS Homo sapiens
70 GGH 8836
Affinity Capture-MS Homo sapiens
71 TBC1D10B 26000
Proximity Label-MS Homo sapiens
72 PRKCZ 5590
Biochemical Activity Homo sapiens
73 TMEM199  
Proximity Label-MS Homo sapiens
74 ATP6AP2 10159
Proximity Label-MS Homo sapiens
75 YWHAZ 7534
Co-fractionation Homo sapiens
76 FKBP8 23770
Proximity Label-MS Homo sapiens
77 AAAS 8086
Proximity Label-MS Homo sapiens
78 PLS1 5357
Proximity Label-MS Homo sapiens
79 TMCO1 54499
Proximity Label-MS Homo sapiens
80 ABCC1 4363
Proximity Label-MS Homo sapiens
81 STMN1 3925
Affinity Capture-MS Homo sapiens
82 CTNNA1 1495
Proximity Label-MS Homo sapiens
83 KIDINS220 57498
Proximity Label-MS Homo sapiens
84 EFNB2 1948
Proximity Label-MS Homo sapiens
85 CDC42EP4  
Proximity Label-MS Homo sapiens
86 STUB1 10273
Proximity Label-MS Homo sapiens
87 FLVCR1 28982
Proximity Label-MS Homo sapiens
88 DENND6A 201627
Proximity Label-MS Homo sapiens
89 HSPE1 3336
Affinity Capture-MS Homo sapiens
90 GPRIN3  
Proximity Label-MS Homo sapiens
91 PSD3 23362
Proximity Label-MS Homo sapiens
92 TMEM57  
Proximity Label-MS Homo sapiens
93 WDR77 79084
Affinity Capture-MS Homo sapiens
94 AGPAT9  
Proximity Label-MS Homo sapiens
95 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
96 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
97 TKT 7086
Affinity Capture-MS Homo sapiens
98 HSP90AA1 3320
Co-fractionation Homo sapiens
99 RAB11FIP1 80223
Proximity Label-MS Homo sapiens
100 ITGA2 3673
Proximity Label-MS Homo sapiens
101 VAMP7 6845
Proximity Label-MS Homo sapiens
102 RABL3 285282
Proximity Label-MS Homo sapiens
103 HM13 81502
Proximity Label-MS Homo sapiens
104 PHACTR4 65979
Proximity Label-MS Homo sapiens
105 GOLGA5 9950
Proximity Label-MS Homo sapiens
106 CDK4 1019
Biochemical Activity Homo sapiens
107 MARK1 4139
Proximity Label-MS Homo sapiens
108 ATP5B 506
Proximity Label-MS Homo sapiens
109 RAB13 5872
Proximity Label-MS Homo sapiens
110 ERICH5  
Proximity Label-MS Homo sapiens
111 CEP78 84131
Affinity Capture-MS Homo sapiens
112 EPHA2 1969
Proximity Label-MS Homo sapiens
113 EI24  
Proximity Label-MS Homo sapiens
114 PRAF2 11230
Proximity Label-MS Homo sapiens
115 VANGL1 81839
Proximity Label-MS Homo sapiens
116 SCAMP3 10067
Proximity Label-MS Homo sapiens
117 ACBD3 64746
Proximity Label-MS Homo sapiens
118 UNC13B 10497
Proximity Label-MS Homo sapiens
119 SNAP29 9342
Proximity Label-MS Homo sapiens
120 GNAI3 2773
Proximity Label-MS Homo sapiens
121 USP6NL 9712
Proximity Label-MS Homo sapiens
122 ANP32A 8125
Affinity Capture-MS Homo sapiens
123 ARHGAP39  
Affinity Capture-MS Homo sapiens
124 LAMP3  
Proximity Label-MS Homo sapiens
125 KCTD10 83892
Affinity Capture-MS Homo sapiens
126 ARL6IP5 10550
Proximity Label-MS Homo sapiens
127 RPA2 6118
Co-fractionation Homo sapiens
128 ARFGAP2 84364
Proximity Label-MS Homo sapiens
129 NACA 4666
Affinity Capture-MS Homo sapiens
130 DBN1 1627
Co-fractionation Homo sapiens
131 DTNA  
Proximity Label-MS Homo sapiens
132 PHOSPHO1  
Affinity Capture-MS Homo sapiens
133 CNP 1267
Proximity Label-MS Homo sapiens
134 VAMP2 6844
Proximity Label-MS Homo sapiens
135 MARC2 54996
Proximity Label-MS Homo sapiens
136 RPS3 6188
Proximity Label-MS Homo sapiens
137 VANGL2  
Proximity Label-MS Homo sapiens
138 PTDSS1 9791
Proximity Label-MS Homo sapiens
139 PGK1 5230
Affinity Capture-MS Homo sapiens
140 WDR41  
Proximity Label-MS Homo sapiens
141 ELOVL2  
Proximity Label-MS Homo sapiens
142 IQGAP1 8826
Proximity Label-MS Homo sapiens
143 STEAP3 55240
Proximity Label-MS Homo sapiens
144 PTPN14 5784
Proximity Label-MS Homo sapiens
145 PHB 5245
Proximity Label-MS Homo sapiens
146 MPP1 4354
Proximity Label-MS Homo sapiens
147 PALM 5064
Proximity Label-MS Homo sapiens
148 HK1 3098
Proximity Label-MS Homo sapiens
149 YWHAB 7529
Affinity Capture-MS Homo sapiens
150 B3GALTL 145173
Co-fractionation Homo sapiens
151 KIAA1715 80856
Proximity Label-MS Homo sapiens
152 PFN1 5216
Affinity Capture-MS Homo sapiens
153 CALM2 805
Co-crystal Structure Homo sapiens
154 CHMP7 91782
Proximity Label-MS Homo sapiens
155 SLC1A5 6510
Proximity Label-MS Homo sapiens
156 VPS45 11311
Proximity Label-MS Homo sapiens
157 RAI14 26064
Proximity Label-MS Homo sapiens
158 MSX2  
Affinity Capture-MS Homo sapiens
159 LYN 4067
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
160 TRIM24  
Affinity Capture-MS Homo sapiens
161 JAM3 83700
Proximity Label-MS Homo sapiens
162 ADD2 119
Proximity Label-MS Homo sapiens
163 MB21D2  
Proximity Label-MS Homo sapiens
164 CDKAL1  
Proximity Label-MS Homo sapiens
165 RELL1 768211
Proximity Label-MS Homo sapiens
166 SCARB1 949
Proximity Label-MS Homo sapiens
167 RAP1A 5906
Proximity Label-MS Homo sapiens
168 LAMP1 3916
Proximity Label-MS Homo sapiens
169 RAB2A 5862
Proximity Label-MS Homo sapiens
170 NMT2 9397
Proximity Label-MS Homo sapiens
171 PREB 10113
Proximity Label-MS Homo sapiens
172 STX5 6811
Proximity Label-MS Homo sapiens
173 Ksr1  
Affinity Capture-MS Mus musculus
174 NDC1 55706
Proximity Label-MS Homo sapiens
175 PTPN11 5781
Co-fractionation Homo sapiens
176 SCD5  
Proximity Label-MS Homo sapiens
177 TMPO 7112
Proximity Label-MS Homo sapiens
178 RAB5A 5868
Proximity Label-MS Homo sapiens
179 RAB11A 8766
Proximity Label-MS Homo sapiens
180 PRKAR2A 5576
Proximity Label-MS Homo sapiens
181 CDC42EP1 11135
Proximity Label-MS Homo sapiens
182 RICTOR 253260
Proximity Label-MS Homo sapiens
183 EGFR 1956
Proximity Label-MS Homo sapiens
184 BCAP31 10134
Proximity Label-MS Homo sapiens
185 SPTBN1 6711
Proximity Label-MS Homo sapiens
186 ARFIP1 27236
Proximity Label-MS Homo sapiens
187 PLEKHA5 54477
Proximity Label-MS Homo sapiens
188 SCYL2 55681
Proximity Label-MS Homo sapiens
189 PCDH7 5099
Proximity Label-MS Homo sapiens
190 CDK2 1017
Biochemical Activity Homo sapiens
191 RFT1 91869
Proximity Label-MS Homo sapiens
192 MYC  
Affinity Capture-MS Homo sapiens
193 FAM91A1 157769
Proximity Label-MS Homo sapiens
194 SLC3A2 6520
Proximity Label-MS Homo sapiens
195 PKP4 8502
Proximity Label-MS Homo sapiens
196 FAM134B 54463
Proximity Label-MS Homo sapiens
197 MICALL1 85377
Proximity Label-MS Homo sapiens
198 SLC6A15 55117
Proximity Label-MS Homo sapiens
199 VRK2 7444
Proximity Label-MS Homo sapiens
200 PEAK1 79834
Proximity Label-MS Homo sapiens
201 FKBP3 2287
Affinity Capture-MS Homo sapiens
202 DDRGK1 65992
Proximity Label-MS Homo sapiens
203 RHOB 388
Proximity Label-MS Homo sapiens
204 WDR44 54521
Proximity Label-MS Homo sapiens
205 PGAM1 5223
Affinity Capture-MS Homo sapiens
206 CCDC88A 55704
Proximity Label-MS Homo sapiens
207 PODXL 5420
Proximity Label-MS Homo sapiens
208 LEMD3  
Proximity Label-MS Homo sapiens
209 CPNE8 144402
Proximity Label-MS Homo sapiens
210 OSBPL8 114882
Proximity Label-MS Homo sapiens
211 TFRC 7037
Proximity Label-MS Homo sapiens
212 EEF1A1 1915
Co-fractionation Homo sapiens
213 SLC16A1 6566
Proximity Label-MS Homo sapiens
214 MARK3 4140
Proximity Label-MS Homo sapiens
215 ADD3 120
Proximity Label-MS Homo sapiens
216 TMEM51 55092
Proximity Label-MS Homo sapiens
217 SUN1 23353
Proximity Label-MS Homo sapiens
218 PLXNB2 23654
Proximity Label-MS Homo sapiens
219 PRKCSH 5589
Affinity Capture-MS Homo sapiens
220 GAB1  
Proximity Label-MS Homo sapiens
221 SLC38A2 54407
Proximity Label-MS Homo sapiens
222 TXNDC16 57544
Affinity Capture-MS Homo sapiens
223 PGRMC1 10857
Proximity Label-MS Homo sapiens
224 VTI1A 143187
Proximity Label-MS Homo sapiens
225 SPP1 6696
Two-hybrid Homo sapiens
226 SLCO4A1 28231
Proximity Label-MS Homo sapiens
227 ARF5 381
Proximity Label-MS Homo sapiens
228 NSDHL 50814
Proximity Label-MS Homo sapiens
229 PSME3 10197
Co-fractionation Homo sapiens
230 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
231 CDK1 983
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
232 MMGT1 93380
Proximity Label-MS Homo sapiens
233 AUP1 550
Proximity Label-MS Homo sapiens
234 AHCYL2 23382
Proximity Label-MS Homo sapiens
235 BSG 682
Proximity Label-MS Homo sapiens
236 REPS1 85021
Proximity Label-MS Homo sapiens
237 KIAA0754  
Proximity Label-MS Homo sapiens
238 ATP1A1 476
Proximity Label-MS Homo sapiens
239 TMEM109 79073
Proximity Label-MS Homo sapiens
240 SLC9A3R1 9368
Proximity Label-MS Homo sapiens
241 YKT6 10652
Proximity Label-MS Homo sapiens
242 ARF1 375
Proximity Label-MS Homo sapiens
243 ANK3  
Proximity Label-MS Homo sapiens
244 CTNND1 1500
Proximity Label-MS Homo sapiens
245 CKAP4 10970
Proximity Label-MS Homo sapiens
246 ATP13A1 57130
Proximity Label-MS Homo sapiens
247 RAB23 51715
Proximity Label-MS Homo sapiens
248 PTPRG 5793
Proximity Label-MS Homo sapiens
249 CLCN7 1186
Proximity Label-MS Homo sapiens
250 ZDHHC5 25921
Proximity Label-MS Homo sapiens
251 ANK2 287
Proximity Label-MS Homo sapiens
252 SNRPE 6635
Proximity Label-MS Homo sapiens
253 OCLN 100506658
Proximity Label-MS Homo sapiens
254 PTMA 5757
Affinity Capture-MS Homo sapiens
255 TPD52L2 7165
Proximity Label-MS Homo sapiens
256 EFR3A 23167
Proximity Label-MS Homo sapiens
257 EPB41L3 23136
Proximity Label-MS Homo sapiens
258 EPB41L5 57669
Proximity Label-MS Homo sapiens
259 ADGRL2 23266
Proximity Label-MS Homo sapiens
260 ROBO1 6091
Proximity Label-MS Homo sapiens
261 PTPN1 5770
Proximity Label-MS Homo sapiens
262 PEBP1 5037
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
263 ANKS1A 23294
Proximity Label-MS Homo sapiens
264 TMX1 81542
Proximity Label-MS Homo sapiens
265 PI4KA 5297
Proximity Label-MS Homo sapiens
266 PARK2  
Affinity Capture-MS Homo sapiens
267 TEX264 51368
Proximity Label-MS Homo sapiens
268 RDX 5962
Proximity Label-MS Homo sapiens
269 MLLT4 4301
Proximity Label-MS Homo sapiens
270 TCEB2 6923
Co-fractionation Homo sapiens
271 PAK4 10298
Proximity Label-MS Homo sapiens
272 FAM171A2 284069
Proximity Label-MS Homo sapiens
273 NUMBL 9253
Proximity Label-MS Homo sapiens
274 DSC2 1824
Proximity Label-MS Homo sapiens
275 SSR1 6745
Proximity Label-MS Homo sapiens
276 DMD 1756
Proximity Label-MS Homo sapiens
277 CCDC47 57003
Proximity Label-MS Homo sapiens
278 SLC19A1 6573
Proximity Label-MS Homo sapiens
279 CALR 811
Affinity Capture-MS Homo sapiens
280 MAVS 57506
Proximity Label-MS Homo sapiens
281 ESYT2 57488
Proximity Label-MS Homo sapiens
282 GPRC5C 55890
Proximity Label-MS Homo sapiens
283 ATP13A3 79572
Proximity Label-MS Homo sapiens
284 GPRIN1 114787
Proximity Label-MS Homo sapiens
285 RBM8A 9939
Affinity Capture-MS Homo sapiens
286 TMEM209 84928
Proximity Label-MS Homo sapiens
287 DHRS7 51635
Proximity Label-MS Homo sapiens
288 PLEKHA1 59338
Proximity Label-MS Homo sapiens
289 PALD1 27143
Proximity Label-MS Homo sapiens
290 SLC30A1 7779
Proximity Label-MS Homo sapiens
291 NF2 4771
Proximity Label-MS Homo sapiens
292 SLC1A3 6507
Proximity Label-MS Homo sapiens
293 IRS4 8471
Proximity Label-MS Homo sapiens
294 ITGA6 3655
Proximity Label-MS Homo sapiens
295 UHMK1  
Affinity Capture-Western Homo sapiens
296 CXADR 1525
Proximity Label-MS Homo sapiens
297 CHCHD3 54927
Proximity Label-MS Homo sapiens
298 CAP1 10487
Co-fractionation Homo sapiens
299 DNAJC5 80331
Proximity Label-MS Homo sapiens
300 NUMB 8650
Proximity Label-MS Homo sapiens
301 NTRK1 4914
Affinity Capture-MS Homo sapiens
302 TPI1 7167
Affinity Capture-MS Homo sapiens
303 ATP5C1 509
Proximity Label-MS Homo sapiens
304 EEF1E1 9521
Proximity Label-MS Homo sapiens
305 CCDC8  
Proximity Label-MS Homo sapiens
306 TACC1 6867
Proximity Label-MS Homo sapiens
307 RAB3GAP1 22930
Proximity Label-MS Homo sapiens
308 ARL13B 200894
Proximity Label-MS Homo sapiens
309 SLC4A7 9497
Proximity Label-MS Homo sapiens
310 ZBTB2 57621
Affinity Capture-MS Homo sapiens
311 SMCR8 140775
Proximity Label-MS Homo sapiens
312 SRPR 6734
Proximity Label-MS Homo sapiens
313 OCRL 4952
Proximity Label-MS Homo sapiens
314 AMDHD2 51005
Co-fractionation Homo sapiens
315 FERMT2 10979
Proximity Label-MS Homo sapiens
316 ANXA5 308
Affinity Capture-MS Homo sapiens
317 VAMP3 9341
Proximity Label-MS Homo sapiens
318 STIM1 6786
Proximity Label-MS Homo sapiens
319 CALM1 801
Affinity Capture-MS Homo sapiens
320 BAIAP2L1 55971
Proximity Label-MS Homo sapiens
321 OCIAD1 54940
Proximity Label-MS Homo sapiens
322 OSBPL11 114885
Proximity Label-MS Homo sapiens
323 CDC42BPA 8476
Proximity Label-MS Homo sapiens
324 MYO1D 4642
Proximity Label-MS Homo sapiens
325 PTPN13 5783
Proximity Label-MS Homo sapiens
326 EPB41 2035
Proximity Label-MS Homo sapiens
327 PALM2-AKAP2 445815
Proximity Label-MS Homo sapiens
328 RPN1 6184
Proximity Label-MS Homo sapiens
329 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
330 SEPT7 989
Proximity Label-MS Homo sapiens
331 HSPD1 3329
Cross-Linking-MS (XL-MS) Homo sapiens
332 HLA-A 3105
Proximity Label-MS Homo sapiens
333 FAM114A2  
Proximity Label-MS Homo sapiens
334 CASKIN2  
Proximity Label-MS Homo sapiens
335 TPM3 7170
Affinity Capture-MS Homo sapiens
336 PIP5K1A 8394
Proximity Label-MS Homo sapiens
337 MBOAT7 79143
Proximity Label-MS Homo sapiens
338 DEPDC1B 55789
Proximity Label-MS Homo sapiens
339 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
340 FBXW11  
Affinity Capture-MS Homo sapiens
341 ALDH3A2 224
Proximity Label-MS Homo sapiens
342 GPR89A  
Proximity Label-MS Homo sapiens
343 RAB3GAP2 25782
Proximity Label-MS Homo sapiens
344 JUP 3728
Proximity Label-MS Homo sapiens
345 SEC23IP 11196
Proximity Label-MS Homo sapiens
346 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
347 PVRL2 5819
Proximity Label-MS Homo sapiens
348 SPTBN2 6712
Proximity Label-MS Homo sapiens
349 FAM171B  
Proximity Label-MS Homo sapiens
350 LSR 51599
Proximity Label-MS Homo sapiens
351 HNRNPM 4670
Co-fractionation Homo sapiens
352 EFNB1 1947
Proximity Label-MS Homo sapiens
353 DFFB  
Co-fractionation Homo sapiens
354 SNAPIN 23557
Proximity Label-MS Homo sapiens
355 C11orf52 91894
Proximity Label-MS Homo sapiens
356 RPL34 6164
Proximity Label-MS Homo sapiens
357 PDZD8 118987
Proximity Label-MS Homo sapiens
358 MIF 4282
Affinity Capture-MS Homo sapiens
359 DNAJC5B  
Proximity Label-MS Homo sapiens
360 FRS2 10818
Proximity Label-MS Homo sapiens
361 RAB7A 7879
Proximity Label-MS Homo sapiens
362 TMEM38B  
Proximity Label-MS Homo sapiens
363 RPRD1B 58490
Affinity Capture-MS Homo sapiens
364 AGPAT6 137964
Proximity Label-MS Homo sapiens
365 STT3B 201595
Proximity Label-MS Homo sapiens
366 SNX2 6643
Proximity Label-MS Homo sapiens
367 CAV1 857
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
368 NOTCH1 4851
Proximity Label-MS Homo sapiens
369 SNX3 8724
Proximity Label-MS Homo sapiens
370 HLA-C 3107
Proximity Label-MS Homo sapiens
371 UBE2H 7328
Affinity Capture-MS Homo sapiens
372 SLC29A1 2030
Proximity Label-MS Homo sapiens
373 C1orf198 84886
Proximity Label-MS Homo sapiens
374 ANKLE2 23141
Proximity Label-MS Homo sapiens
375 ATPIF1 93974
Affinity Capture-MS Homo sapiens
376 SNAP23 8773
Proximity Label-MS Homo sapiens
377 VAPA 9218
Proximity Label-MS Homo sapiens
378 CTSB  
Biochemical Activity Bos taurus
379 ARFGAP3 26286
Proximity Label-MS Homo sapiens
380 VPS13A 23230
Proximity Label-MS Homo sapiens
381 RPL15 6138
Proximity Label-MS Homo sapiens
382 LAMP2 3920
Proximity Label-MS Homo sapiens
383 BASP1 10409
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
384 LNPEP 4012
Proximity Label-MS Homo sapiens
385 SNX6 58533
Proximity Label-MS Homo sapiens
386 SLC12A2 6558
Proximity Label-MS Homo sapiens
387 RAB6A 5870
Proximity Label-MS Homo sapiens
388 TOMM22 56993
Proximity Label-MS Homo sapiens
389 MARK2 2011
Proximity Label-MS Homo sapiens
390 WDR11 55717
Proximity Label-MS Homo sapiens
391 SLC39A10 57181
Proximity Label-MS Homo sapiens
392 WDR20 91833
Proximity Label-MS Homo sapiens
393 STIM2 57620
Proximity Label-MS Homo sapiens
394 ANP32B 10541
Affinity Capture-MS Homo sapiens
395 YES1 7525
Proximity Label-MS Homo sapiens
396 CPD 1362
Proximity Label-MS Homo sapiens
397 SCRIB 23513
Proximity Label-MS Homo sapiens
398 STX7 8417
Proximity Label-MS Homo sapiens
399 ADD1 118
Proximity Label-MS Homo sapiens
400 STX18 53407
Proximity Label-MS Homo sapiens
401 PGRMC2 10424
Proximity Label-MS Homo sapiens
402 MYO1B 4430
Proximity Label-MS Homo sapiens
403 GOPC 57120
Proximity Label-MS Homo sapiens
404 VAT1 10493
Proximity Label-MS Homo sapiens
405 RAB35 11021
Proximity Label-MS Homo sapiens
406 MYCN  
Affinity Capture-MS Homo sapiens
407 FAF2 23197
Proximity Label-MS Homo sapiens
408 TMEM2 23670
Proximity Label-MS Homo sapiens
409 NEDD4 4734
Affinity Capture-MS Homo sapiens
410 VAMP8 8673
Proximity Label-MS Homo sapiens
411 LAMTOR1 55004
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
412 COBLL1 22837
Proximity Label-MS Homo sapiens
413 LRRC59 55379
Proximity Label-MS Homo sapiens
414 CDK16 5127
Proximity Label-MS Homo sapiens
415 PPIB 5479
Affinity Capture-MS Homo sapiens
416 NCAM1 4684
Proximity Label-MS Homo sapiens
417 EMD 2010
Proximity Label-MS Homo sapiens
418 ALDH1A2 8854
Proximity Label-MS Homo sapiens
419 HSP90B1 7184
Affinity Capture-MS Homo sapiens
420 TNKS1BP1 85456
Proximity Label-MS Homo sapiens
421 ATF2  
Affinity Capture-MS Homo sapiens
422 CNNM3 26505
Proximity Label-MS Homo sapiens
423 PAG1 55824
Proximity Label-MS Homo sapiens
424 NOC2L 26155
Proximity Label-MS Homo sapiens
425 APOL2 23780
Proximity Label-MS Homo sapiens
426 SWAP70 23075
Proximity Label-MS Homo sapiens
427 VCP 7415
Affinity Capture-MS Homo sapiens
428 HMGN1  
Affinity Capture-MS Homo sapiens
429 UBQLN2 29978
Co-fractionation Homo sapiens
430 SUMO2 6613
Affinity Capture-MS Homo sapiens
431 AP1B1 162
Proximity Label-MS Homo sapiens
432 SLC7A2 6542
Proximity Label-MS Homo sapiens
433 STX6 10228
Proximity Label-MS Homo sapiens
434 LMF2 91289
Proximity Label-MS Homo sapiens
435 MTMR1 8776
Proximity Label-MS Homo sapiens
436 ATP2B4 493
Proximity Label-MS Homo sapiens
437 DLG1 1739
Proximity Label-MS Homo sapiens
438 ANKRD26 22852
Proximity Label-MS Homo sapiens
439 SLC33A1 9197
Proximity Label-MS Homo sapiens
440 SLC7A1 6541
Proximity Label-MS Homo sapiens
441 CTNNAL1 8727
Proximity Label-MS Homo sapiens
442 COX4I1 1327
Proximity Label-MS Homo sapiens
443 CACHD1  
Proximity Label-MS Homo sapiens
444 GOLGA3 2802
Proximity Label-MS Homo sapiens
445 CLINT1 9685
Proximity Label-MS Homo sapiens
446 VAPB 9217
Proximity Label-MS Homo sapiens
447 SLC39A6 25800
Proximity Label-MS Homo sapiens
448 ATP2B1 490
Proximity Label-MS Homo sapiens
449 SLC20A2 6575
Proximity Label-MS Homo sapiens
450 HMOX2 3163
Proximity Label-MS Homo sapiens
451 CTNNB1 1499
Proximity Label-MS Homo sapiens
452 FAM171A1 221061
Proximity Label-MS Homo sapiens
453 CCNE1  
Biochemical Activity Homo sapiens
454 PDIA3 2923
Affinity Capture-MS Homo sapiens
455 IGF2R 3482
Proximity Label-MS Homo sapiens
456 SLC7A5 8140
Proximity Label-MS Homo sapiens
457 ARF6 382
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
458 EHBP1 23301
Proximity Label-MS Homo sapiens
459 EPHA7 2045
Proximity Label-MS Homo sapiens
460 PRKACA 5566
Co-fractionation Homo sapiens
461 KIRREL 55243
Proximity Label-MS Homo sapiens
462 ACSL3 2181
Proximity Label-MS Homo sapiens
463 LMNB1 4001
Proximity Label-MS Homo sapiens
464 AKAP5  
Proximity Label-MS Homo sapiens
465 PPFIBP1 8496
Proximity Label-MS Homo sapiens
466 SIRT2 22933
Proximity Label-MS Homo sapiens
467 FNDC3A 22862
Proximity Label-MS Homo sapiens
468 SLC7A11 23657
Proximity Label-MS Homo sapiens
469 KRAS 3845
Proximity Label-MS Homo sapiens
470 TOB1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
471 KIAA0319L 79932
Proximity Label-MS Homo sapiens
472 FSCN1 6624
Affinity Capture-MS Homo sapiens
473 PPFIA1 8500
Proximity Label-MS Homo sapiens
474 FARP1 10160
Proximity Label-MS Homo sapiens
475 KIAA1522 57648
Proximity Label-MS Homo sapiens
476 LBR 3930
Proximity Label-MS Homo sapiens
477 SPTAN1 6709
Proximity Label-MS Homo sapiens
478 USE1 55850
Proximity Label-MS Homo sapiens
479 UBXN4 23190
Proximity Label-MS Homo sapiens
480 PDIA4 9601
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
481 LMAN1 3998
Proximity Label-MS Homo sapiens
482 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
483 SLC39A14 23516
Proximity Label-MS Homo sapiens
484 EPB41L2 2037
Proximity Label-MS Homo sapiens
485 DOLPP1  
Proximity Label-MS Homo sapiens
486 RAB1A 5861
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
487 ROR2 4920
Proximity Label-MS Homo sapiens
488 UBIAD1 29914
Proximity Label-MS Homo sapiens
489 RPS28 6234
Affinity Capture-MS Homo sapiens
490 PDLIM5 10611
Co-fractionation Homo sapiens
491 SLC25A4 291
Proximity Label-MS Homo sapiens
492 RPS23 6228
Proximity Label-MS Homo sapiens
493 SLC38A1 81539
Proximity Label-MS Homo sapiens
494 PINK1  
Affinity Capture-MS Homo sapiens
495 SLC6A8 6535
Proximity Label-MS Homo sapiens
496 CYB5R3 1727
Proximity Label-MS Homo sapiens
497 PIK3R2 5296
Proximity Label-MS Homo sapiens
498 DNAJC1 64215
Proximity Label-MS Homo sapiens
499 HNRNPU 3192
Co-fractionation Homo sapiens
500 TRIM29 23650
Affinity Capture-MS Homo sapiens
501 ESYT1 23344
Proximity Label-MS Homo sapiens
502 VEZT 55591
Proximity Label-MS Homo sapiens
503 ALDOA 226
Affinity Capture-MS Homo sapiens
504 DSG2 1829
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here