Gene description for PALD1
Gene name phosphatase domain containing, paladin 1
Gene symbol PALD1
Other names/aliases KIAA1274
PALD
Species Homo sapiens
 Database cross references - PALD1
ExoCarta ExoCarta_27143
Vesiclepedia VP_27143
Entrez Gene 27143
HGNC 23530
MIM 614656
UniProt Q9ULE6  
 PALD1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for PALD1
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IBA
    protein binding GO:0005515 IPI
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified PALD1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PALD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TACR3  
Affinity Capture-MS Homo sapiens
2 SPATA5L1 79029
Affinity Capture-MS Homo sapiens
3 GJD3  
Proximity Label-MS Homo sapiens
4 MAP2K2 5605
Affinity Capture-MS Homo sapiens
5 RAB35 11021
Proximity Label-MS Homo sapiens
6 IL13RA2 3598
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 INTS5 80789
Affinity Capture-MS Homo sapiens
8 NPHP3 27031
Affinity Capture-MS Homo sapiens
9 METTL7A 25840
Proximity Label-MS Homo sapiens
10 LAMTOR1 55004
Proximity Label-MS Homo sapiens
11 MARCKS 4082
Proximity Label-MS Homo sapiens
12 BAG2 9532
Affinity Capture-MS Homo sapiens
13 RAB4A 5867
Proximity Label-MS Homo sapiens
14 PXMP2  
Proximity Label-MS Homo sapiens
15 GADD45A  
Affinity Capture-MS Homo sapiens
16 RAB9A 9367
Proximity Label-MS Homo sapiens
17 C12orf74  
Affinity Capture-MS Homo sapiens
18 SUN1 23353
Affinity Capture-MS Homo sapiens
19 MTCH2 23788
Proximity Label-MS Homo sapiens
20 HDHD1  
Affinity Capture-MS Homo sapiens
21 CUL3 8452
Affinity Capture-MS Homo sapiens
22 EMD 2010
Proximity Label-MS Homo sapiens
23 LAMP2 3920
Proximity Label-MS Homo sapiens
24 ARF6 382
Proximity Label-MS Homo sapiens
25 PTPN1 5770
Proximity Label-MS Homo sapiens
26 AQP3  
Affinity Capture-MS Homo sapiens
27 LGALS7 3963
Affinity Capture-MS Homo sapiens
28 NPAS2  
Affinity Capture-MS Homo sapiens
29 OCIAD1 54940
Proximity Label-MS Homo sapiens
30 TLR9  
Affinity Capture-MS Homo sapiens
31 IRF7  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
32 RPA3 6119
Proximity Label-MS Homo sapiens
33 ANGPTL7 10218
Affinity Capture-MS Homo sapiens
34 ZBP1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
35 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 C5orf30  
Affinity Capture-MS Homo sapiens
37 CAMK2B 816
Affinity Capture-MS Homo sapiens
38 SEC62 7095
Proximity Label-MS Homo sapiens
39 FIS1 51024
Proximity Label-MS Homo sapiens
40 RAB11A 8766
Proximity Label-MS Homo sapiens
41 INTS7  
Affinity Capture-MS Homo sapiens
42 ALPP 250
Affinity Capture-MS Homo sapiens
43 UNC119 9094
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 KRAS 3845
Proximity Label-MS Homo sapiens
45 NXPH3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 RHOB 388
Proximity Label-MS Homo sapiens
47 DYNLL2 140735
Affinity Capture-MS Homo sapiens
48 INF2 64423
Affinity Capture-MS Homo sapiens
49 RHOT2 89941
Proximity Label-MS Homo sapiens
50 AKAP1 8165
Proximity Label-MS Homo sapiens
51 SEC61B 10952
Proximity Label-MS Homo sapiens
52 DERL1 79139
Proximity Label-MS Homo sapiens
53 SLC25A46 91137
Proximity Label-MS Homo sapiens
54 UNC119B 84747
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PALD1 is involved
No pathways found





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