Gene description for ANGPTL7
Gene name angiopoietin-like 7
Gene symbol ANGPTL7
Other names/aliases AngX
CDT6
dJ647M16.1
Species Homo sapiens
 Database cross references - ANGPTL7
ExoCarta ExoCarta_10218
Vesiclepedia VP_10218
Entrez Gene 10218
HGNC 24078
UniProt O43827  
 ANGPTL7 identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for ANGPTL7
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IDA
Biological Process
    response to oxidative stress GO:0006979 TAS
    blood coagulation GO:0007596 IEA
    negative regulation of vasculature development involved in avascular cornea development in camera-type eye GO:1901346 IMP
    regulation of extracellular matrix organization GO:1903053 IMP
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular space GO:0005615 IBA
    collagen-containing extracellular matrix GO:0062023 IBA
 Experiment description of studies that identified ANGPTL7 in sEVs
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ANGPTL7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EDEM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 NMT1 4836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CCT3 7203
Affinity Capture-MS Homo sapiens
4 CCT2 10576
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 PALD1 27143
Affinity Capture-MS Homo sapiens
6 CCT6A 908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TCP1 6950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 TFAP4 7023
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CCT6B 10693
Affinity Capture-MS Homo sapiens
10 KBTBD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 EDEM3 80267
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 APP 351
Reconstituted Complex Homo sapiens
13 CCT7 10574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 ANGPTL7 10218
Co-purification Homo sapiens
Co-purification Homo sapiens
15 GNB2 2783
Affinity Capture-MS Homo sapiens
16 PCK1 5105
Affinity Capture-MS Homo sapiens
17 HELZ 9931
Affinity Capture-MS Homo sapiens
18 ETV3  
Affinity Capture-MS Homo sapiens
19 ACTN2 88
Two-hybrid Homo sapiens
20 CLPB 81570
Affinity Capture-MS Homo sapiens
21 HSD17B8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 CAMK2B 816
Affinity Capture-MS Homo sapiens
23 TXNDC11 51061
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANGPTL7 is involved
No pathways found





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