Gene description for PCK1
Gene name	phosphoenolpyruvate carboxykinase 1 (soluble)
Gene symbol	PCK1
Other names/aliases	PEPCK-C PEPCK1 PEPCKC
Species	Homo sapiens
Database cross references - PCK1
ExoCarta	ExoCarta_5105
Vesiclepedia	VP_5105
Entrez Gene	5105
HGNC	8724
MIM	614168
UniProt	P35558
PCK1 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Urine	19056867

Gene ontology annotations for PCK1

Molecular Function     magnesium ion binding GO:0000287 IDA     phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613 EXP     phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613 IBA     phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613 IDA     phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613 IMP     phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613 ISS     GTP binding GO:0005525 IDA     manganese ion binding GO:0030145 IBA     manganese ion binding GO:0030145 IDA     carboxylic acid binding GO:0031406 IDA     protein serine kinase activity (using GTP as donor) GO:0106264 IDA Biological Process     glucose metabolic process GO:0006006 IMP     gluconeogenesis GO:0006094 IBA     gluconeogenesis GO:0006094 IDA     gluconeogenesis GO:0006094 IEA     gluconeogenesis GO:0006094 IMP     gluconeogenesis GO:0006094 ISS     gluconeogenesis GO:0006094 TAS     oxaloacetate metabolic process GO:0006107 IBA     oxaloacetate metabolic process GO:0006107 IDA     response to bacterium GO:0009617 IEA     peptidyl-serine phosphorylation GO:0018105 IDA     propionate catabolic process GO:0019543 IBA     response to insulin GO:0032868 IDA     cellular response to insulin stimulus GO:0032869 IBA     cellular response to insulin stimulus GO:0032869 IDA     glucose homeostasis GO:0042593 ISS     response to starvation GO:0042594 IBA     positive regulation of memory T cell differentiation GO:0043382 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     glyceraldehyde-3-phosphate biosynthetic process GO:0046166 IEA     glycerol biosynthetic process from pyruvate GO:0046327 IBA     glycerol biosynthetic process from pyruvate GO:0046327 ISS     positive regulation of lipid biosynthetic process GO:0046889 IDA     regulation of lipid biosynthetic process GO:0046890 IDA     cellular response to potassium ion starvation GO:0051365 IEA     hepatocyte differentiation GO:0070365 IBA     cellular response to glucose stimulus GO:0071333 IBA     cellular response to glucose stimulus GO:0071333 IDA     cellular response to dexamethasone stimulus GO:0071549 IBA     tricarboxylic acid metabolic process GO:0072350 IDA Subcellular Localization     cytoplasm GO:0005737 ISS     mitochondrion GO:0005739 IBA     endoplasmic reticulum GO:0005783 IDA     cytosol GO:0005829 IBA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     extracellular exosome GO:0070062 HDA