Gene description for FAF2
Gene name Fas associated factor family member 2
Gene symbol FAF2
Other names/aliases ETEA
UBXD8
UBXN3B
Species Homo sapiens
 Database cross references - FAF2
ExoCarta ExoCarta_23197
Vesiclepedia VP_23197
Entrez Gene 23197
HGNC 24666
UniProt Q96CS3  
 FAF2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for FAF2
Molecular Function
    protein binding GO:0005515 IPI
    protein-macromolecule adaptor activity GO:0030674 IDA
    ubiquitin protein ligase binding GO:0031625 IDA
    lipase binding GO:0035473 IDA
    ubiquitin binding GO:0043130 IBA
    ubiquitin binding GO:0043130 IDA
    lipase inhibitor activity GO:0055102 IDA
Biological Process
    response to unfolded protein GO:0006986 IEA
    retrograde protein transport, ER to cytosol GO:0030970 IMP
    lipid droplet organization GO:0034389 IMP
    stress granule disassembly GO:0035617 IDA
    ERAD pathway GO:0036503 IBA
    ERAD pathway GO:0036503 IMP
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 IDA
    lipid droplet GO:0005811 IDA
    VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IDA
    azurophil granule lumen GO:0035578 TAS
 Experiment description of studies that identified FAF2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for FAF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GJD3  
Proximity Label-MS Homo sapiens
2 NPLOC4 55666
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 UBL4A 8266
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ZFAND2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
5 ATG9A 79065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 MCM9 254394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 VMP1 81671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 KIF20A 10112
Affinity Capture-MS Homo sapiens
9 NPEPPS 9520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 UBC 7316
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
11 CSE1L 1434
Affinity Capture-MS Homo sapiens
12 VPS13C 54832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 WDR26 80232
Affinity Capture-MS Homo sapiens
14 GCN1L1 10985
Affinity Capture-MS Homo sapiens
15 PRKDC 5591
Affinity Capture-MS Homo sapiens
16 LPCAT1 79888
Co-fractionation Homo sapiens
17 PFKL 5211
Affinity Capture-MS Homo sapiens
18 KIF23 9493
Affinity Capture-MS Homo sapiens
19 STOM 2040
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 SEL1L 6400
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
21 CALD1 800
Cross-Linking-MS (XL-MS) Homo sapiens
22 STT3A 3703
Affinity Capture-MS Homo sapiens
23 ABCD3 5825
Affinity Capture-MS Homo sapiens
24 TIMM23B  
Co-fractionation Homo sapiens
25 MARCH5  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 SQLE 6713
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 DNAJB1 3337
Affinity Capture-MS Homo sapiens
28 FAM207A  
Cross-Linking-MS (XL-MS) Homo sapiens
29 SLC25A46 91137
Proximity Label-MS Homo sapiens
30 RNF126  
Affinity Capture-MS Homo sapiens
31 VWA8 23078
Proximity Label-MS Homo sapiens
32 EMC1 23065
Affinity Capture-MS Homo sapiens
33 UNC45A 55898
Affinity Capture-MS Homo sapiens
34 MTCH2 23788
Proximity Label-MS Homo sapiens
35 SAE1 10055
Affinity Capture-MS Homo sapiens
36 ILVBL 10994
Affinity Capture-MS Homo sapiens
37 UBAC2 337867
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
38 PSMD2 5708
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
39 OGT 8473
Reconstituted Complex Homo sapiens
40 CCDC109B 55013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 ENO1 2023
Affinity Capture-MS Homo sapiens
42 CUL2 8453
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
43 AHCTF1 25909
Affinity Capture-MS Homo sapiens
44 VDAC2 7417
Affinity Capture-MS Homo sapiens
45 SEC61B 10952
Proximity Label-MS Homo sapiens
46 YOD1  
Affinity Capture-Western Homo sapiens
47 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
48 UBR2 23304
Affinity Capture-MS Homo sapiens
49 REEP5 7905
Proximity Label-MS Homo sapiens
50 TMPO 7112
Affinity Capture-MS Homo sapiens
51 TARBP1 6894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 LRRC59 55379
Proximity Label-MS Homo sapiens
53 LMNB1 4001
Proximity Label-MS Homo sapiens
54 UBQLN2 29978
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
55 CD274 29126
Affinity Capture-MS Homo sapiens
56 BCAP31 10134
Proximity Label-MS Homo sapiens
57 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
58 GPD2 2820
Co-fractionation Homo sapiens
59 FKBP8 23770
Proximity Label-MS Homo sapiens
60 TUBA4A 7277
Affinity Capture-MS Homo sapiens
61 UBR1 197131
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
62 TMED10 10972
Affinity Capture-MS Homo sapiens
63 RPA3 6119
Proximity Label-MS Homo sapiens
64 CYP2C9  
Proximity Label-MS Homo sapiens
65 COX2 4513
Affinity Capture-MS Homo sapiens
66 KIDINS220 57498
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 PEX3 8504
Proximity Label-MS Homo sapiens
68 HMGCR  
Affinity Capture-MS Homo sapiens
69 PEX11B 8799
Affinity Capture-MS Homo sapiens
70 SUCLG2 8801
Affinity Capture-MS Homo sapiens
71 JMJD7  
Affinity Capture-MS Homo sapiens
72 S100A10 6281
Co-fractionation Homo sapiens
73 TRA2B 6434
Co-fractionation Homo sapiens
74 OS9 10956
Affinity Capture-MS Homo sapiens
75 LMAN1 3998
Proximity Label-MS Homo sapiens
76 OAT 4942
Affinity Capture-MS Homo sapiens
77 PTPN5  
Affinity Capture-MS Homo sapiens
78 RAB2A 5862
Proximity Label-MS Homo sapiens
79 SORT1 6272
Affinity Capture-MS Homo sapiens
80 RAB11A 8766
Proximity Label-MS Homo sapiens
81 ORAI1 84876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 INTS3 65123
Affinity Capture-MS Homo sapiens
83 RAB5C 5878
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
84 NUP85 79902
Affinity Capture-MS Homo sapiens
85 DERL1 79139
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
86 SPRTN  
Affinity Capture-MS Homo sapiens
87 Insr  
Affinity Capture-MS Mus musculus
88 METTL7A 25840
Proximity Label-MS Homo sapiens
89 LAMP3  
Proximity Label-MS Homo sapiens
90 USP13  
Affinity Capture-MS Homo sapiens
91 GJA1 2697
Proximity Label-MS Homo sapiens
92 ARF3 377
Affinity Capture-MS Homo sapiens
93 CAND1 55832
Affinity Capture-MS Homo sapiens
94 SYVN1 84447
Affinity Capture-Western Homo sapiens
95 SETDB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 NDUFS2 4720
Affinity Capture-MS Homo sapiens
97 SPG7  
Affinity Capture-MS Homo sapiens
98 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
99 FIS1 51024
Proximity Label-MS Homo sapiens
100 TIMM23 100287932
Affinity Capture-MS Homo sapiens
101 TIMM17B  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
102 PRC1 9055
Affinity Capture-MS Homo sapiens
103 TMED2 10959
Affinity Capture-MS Homo sapiens
104 GCAT  
Affinity Capture-MS Homo sapiens
105 RGS20 8601
Affinity Capture-MS Homo sapiens
106 TUBA3C 7278
Affinity Capture-MS Homo sapiens
107 TOMM40 10452
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
108 CUL1 8454
Affinity Capture-Western Homo sapiens
109 TRO  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 CBR1 873
Affinity Capture-MS Homo sapiens
111 KIAA1715 80856
Proximity Label-MS Homo sapiens
112 NNT 23530
Affinity Capture-MS Homo sapiens
113 SLC25A10 1468
Affinity Capture-MS Homo sapiens
114 AMFR 267
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
115 FUNDC2 65991
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 TMEM55B 90809
Affinity Capture-MS Homo sapiens
117 PSMD14 10213
Affinity Capture-MS Homo sapiens
118 BAG6 7917
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
119 Ar  
Affinity Capture-MS Mus musculus
120 TMEM43 79188
Affinity Capture-MS Homo sapiens
121 UBR5 51366
Affinity Capture-MS Homo sapiens
122 CDKAL1  
Affinity Capture-MS Homo sapiens
123 TUBA1C 84790
Affinity Capture-MS Homo sapiens
124 DCAF7 10238
Affinity Capture-MS Homo sapiens
125 INTS7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 APOB 338
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
127 CLEC11A 6320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 ATP4A 495
Affinity Capture-MS Homo sapiens
129 UBXN6 80700
Affinity Capture-MS Homo sapiens
130 ABCB7 22
Affinity Capture-MS Homo sapiens
131 FBXL4 26235
Affinity Capture-Western Homo sapiens
132 UFD1L 7353
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 TMED9 54732
Affinity Capture-MS Homo sapiens
134 RPN2 6185
Proximity Label-MS Homo sapiens
135 AIFM1 9131
Proximity Label-MS Homo sapiens
136 CANX 821
Affinity Capture-MS Homo sapiens
137 UBXN7 26043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 SLC25A22  
Co-fractionation Homo sapiens
139 EGFR 1956
Affinity Capture-MS Homo sapiens
140 RIPK4  
Affinity Capture-MS Homo sapiens
141 LARS 51520
Affinity Capture-MS Homo sapiens
142 GDAP1 54332
Co-fractionation Homo sapiens
143 ATP2A1 487
Proximity Label-MS Homo sapiens
144 FAM46A  
Affinity Capture-MS Homo sapiens
145 ACAD9 28976
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 DDB1 1642
Affinity Capture-MS Homo sapiens
147 DDRGK1 65992
Affinity Capture-MS Homo sapiens
148 SLC12A6 9990
Affinity Capture-MS Homo sapiens
149 VIMP 55829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 MCUR1 63933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 TOMM20 9804
Affinity Capture-MS Homo sapiens
152 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 AR 367
Affinity Capture-MS Homo sapiens
154 KRT18 3875
Affinity Capture-MS Homo sapiens
155 CLPP 8192
Proximity Label-MS Homo sapiens
156 UBE3A 7337
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
157 SLC25A16  
Affinity Capture-MS Homo sapiens
158 RRM2 6241
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 PEX19 5824
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 CALU 813
Co-fractionation Homo sapiens
161 XPR1 9213
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 ARF5 381
Affinity Capture-MS Homo sapiens
163 AUP1 550
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
164 ERGIC2 51290
Proximity Label-MS Homo sapiens
165 DAGLB 221955
Affinity Capture-MS Homo sapiens
166 C16orf72 29035
Affinity Capture-MS Homo sapiens
167 ALPP 250
Affinity Capture-MS Homo sapiens
168 EP300 2033
Affinity Capture-MS Homo sapiens
169 KRAS 3845
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
170 ABHD17B 51104
Affinity Capture-MS Homo sapiens
171 CKAP4 10970
Proximity Label-MS Homo sapiens
172 ANKRD46 157567
Affinity Capture-MS Homo sapiens
173 ATAD1 84896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 HACD3 51495
Co-fractionation Homo sapiens
175 INTS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 MTCH1 23787
Proximity Label-MS Homo sapiens
177 TCEB1 6921
Affinity Capture-MS Homo sapiens
178 MARCKS 4082
Proximity Label-MS Homo sapiens
179 PFKP 5214
Affinity Capture-MS Homo sapiens
180 MFN1 55669
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 ARL14EP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 PTPN1 5770
Proximity Label-MS Homo sapiens
183 ARL6IP1 23204
Affinity Capture-MS Homo sapiens
184 STX4 6810
Proximity Label-MS Homo sapiens
185 VRK2 7444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 PJA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 MCM2 4171
Affinity Capture-MS Homo sapiens
188 HLA-B 3106
Affinity Capture-MS Homo sapiens
189 TIMMDC1  
Affinity Capture-MS Homo sapiens
190 RAB3B 5865
Proximity Label-MS Homo sapiens
191 PNPLA6 10908
Affinity Capture-MS Homo sapiens
192 SSR1 6745
Proximity Label-MS Homo sapiens
193 PIGH  
Affinity Capture-MS Homo sapiens
194 COIL  
Proximity Label-MS Homo sapiens
195 NDUFAF1  
Affinity Capture-MS Homo sapiens
196 MAVS 57506
Proximity Label-MS Homo sapiens
197 ESYT2 57488
Affinity Capture-MS Homo sapiens
198 UQCRQ 27089
Co-fractionation Homo sapiens
199 FAS 355
Two-hybrid Homo sapiens
200 INSIG2  
Affinity Capture-MS Homo sapiens
201 NUP155 9631
Proximity Label-MS Homo sapiens
202 PXMP2  
Proximity Label-MS Homo sapiens
203 EPB41L3 23136
Affinity Capture-MS Homo sapiens
204 UBR4 23352
Affinity Capture-MS Homo sapiens
205 CDKN2AIP  
Affinity Capture-MS Homo sapiens
206 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 PTGS2 5743
Affinity Capture-MS Homo sapiens
208 CXADR 1525
Proximity Label-MS Homo sapiens
209 TUBA1A 7846
Affinity Capture-MS Homo sapiens
210 RAB4A 5867
Proximity Label-MS Homo sapiens
211 ABCF2 10061
Affinity Capture-MS Homo sapiens
212 TUBA1B 10376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 SARAF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 RPN1 6184
Proximity Label-MS Homo sapiens
215 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
216 VCPIP1 80124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 ACTG1 71
Affinity Capture-MS Homo sapiens
218 RMDN3 55177
Proximity Label-MS Homo sapiens
219 IPO9 55705
Affinity Capture-MS Homo sapiens
220 MSH2 4436
Affinity Capture-MS Homo sapiens
221 ACADM 34
Affinity Capture-MS Homo sapiens
222 HSD3B7 80270
Proximity Label-MS Homo sapiens
223 NR3C1 2908
Proximity Label-MS Homo sapiens
224 STIM1 6786
Proximity Label-MS Homo sapiens
225 FBXO6 26270
Affinity Capture-MS Homo sapiens
226 YIPF5 81555
Affinity Capture-MS Homo sapiens
227 ECE1 1889
Co-fractionation Homo sapiens
228 OCIAD1 54940
Proximity Label-MS Homo sapiens
229 C17orf80 55028
Proximity Label-MS Homo sapiens
230 TM9SF3 56889
Affinity Capture-MS Homo sapiens
231 RAB9A 9367
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 RNF2  
Affinity Capture-MS Homo sapiens
233 RNF26  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
234 PNPLA2  
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
235 ARAF 369
Affinity Capture-MS Homo sapiens
236 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
237 ACBD5 91452
Proximity Label-MS Homo sapiens
238 UBE2J1 51465
Affinity Capture-Western Homo sapiens
239 UBE2D1 7321
Reconstituted Complex Homo sapiens
240 HIF1A 3091
Affinity Capture-Western Homo sapiens
241 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
242 DMXL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
244 ALDH3A2 224
Affinity Capture-MS Homo sapiens
245 ERLIN1 10613
Affinity Capture-MS Homo sapiens
246 TTC27 55622
Affinity Capture-MS Homo sapiens
247 SLC26A6 65010
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 ALDH1B1 219
Affinity Capture-MS Homo sapiens
249 EDEM1  
Affinity Capture-MS Homo sapiens
250 RPTOR 57521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 TUBB3 10381
Affinity Capture-MS Homo sapiens
252 G3BP1 10146
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
253 ERLIN2 11160
Affinity Capture-MS Homo sapiens
254 PJA2  
Affinity Capture-MS Homo sapiens
255 MTHFD1 4522
Co-fractionation Homo sapiens
256 ERGIC1 57222
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
257 DDX58 23586
Affinity Capture-RNA Homo sapiens
258 UBE3C 9690
Affinity Capture-MS Homo sapiens
259 UFL1 23376
Affinity Capture-MS Homo sapiens
260 NF1 4763
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
261 RAB7A 7879
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 CIT 11113
Affinity Capture-MS Homo sapiens
263 SERBP1 26135
Affinity Capture-MS Homo sapiens
264 TMEM31  
Affinity Capture-MS Homo sapiens
265 VDAC3 7419
Affinity Capture-MS Homo sapiens
266 ATXN3 4287
Affinity Capture-MS Homo sapiens
267 CAV1 857
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 CCRN4L  
Affinity Capture-MS Homo sapiens
269 HLA-C 3107
Affinity Capture-MS Homo sapiens
270 UBE2H 7328
Affinity Capture-MS Homo sapiens
271 INSIG1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
272 HSD17B11 51170
Proximity Label-MS Homo sapiens
273 DERL2 51009
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 MSH6 2956
Affinity Capture-MS Homo sapiens
275 VPS13A 23230
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 MRPL37 51253
Co-fractionation Homo sapiens
277 LAMP2 3920
Proximity Label-MS Homo sapiens
278 PSEN2 5664
Affinity Capture-MS Homo sapiens
279 HSPA5 3309
Affinity Capture-MS Homo sapiens
280 TOMM22 56993
Affinity Capture-MS Homo sapiens
281 KIAA1429 25962
Affinity Capture-MS Homo sapiens
282 B3GAT1  
Proximity Label-MS Homo sapiens
283 EVI5L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 PCK1 5105
Affinity Capture-MS Homo sapiens
285 YES1 7525
Co-fractionation Homo sapiens
286 FBXW7  
Affinity Capture-MS Homo sapiens
287 ACTG2 72
Affinity Capture-MS Homo sapiens
288 SERPINH1 871
Affinity Capture-MS Homo sapiens
289 EXD2  
Proximity Label-MS Homo sapiens
290 DNAJC16  
Proximity Label-MS Homo sapiens
291 RAB35 11021
Proximity Label-MS Homo sapiens
292 FAF2 23197
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
293 HLA-G 3135
Co-fractionation Homo sapiens
294 KRT8 3856
Affinity Capture-MS Homo sapiens
295 HAUS2  
Affinity Capture-MS Homo sapiens
296 EMD 2010
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 RB1CC1 9821
Affinity Capture-MS Homo sapiens
298 TRAM1 23471
Affinity Capture-MS Homo sapiens
299 TMEM159 57146
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 HSP90B1 7184
Affinity Capture-MS Homo sapiens
301 VCP 7415
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
302 POLD3  
Affinity Capture-MS Homo sapiens
303 ATP2C1 27032
Affinity Capture-MS Homo sapiens
304 RHOT2 89941
Proximity Label-MS Homo sapiens
305 ELOVL5 60481
Proximity Label-MS Homo sapiens
306 ATP5B 506
Affinity Capture-MS Homo sapiens
307 ST13 6767
Cross-Linking-MS (XL-MS) Homo sapiens
308 COX4I1 1327
Affinity Capture-MS Homo sapiens
309 OXA1L  
Co-fractionation Homo sapiens
310 ACTN1 87
Co-fractionation Homo sapiens
311 SLC25A24 29957
Co-fractionation Homo sapiens
312 MRPL21 219927
Co-fractionation Homo sapiens
313 VAPB 9217
Affinity Capture-MS Homo sapiens
314 BCKDHB 594
Affinity Capture-MS Homo sapiens
315 PANX1 24145
Proximity Label-MS Homo sapiens
316 UQCRC2 7385
Affinity Capture-MS Homo sapiens
317 STK17B 9262
Affinity Capture-MS Homo sapiens
318 GCDH 2639
Affinity Capture-MS Homo sapiens
319 Bmpr1a  
Affinity Capture-MS Mus musculus
320 MAP3K1 4214
Biochemical Activity Homo sapiens
321 ARF6 382
Proximity Label-MS Homo sapiens
322 TBCD 6904
Affinity Capture-MS Homo sapiens
323 ACADSB 36
Affinity Capture-MS Homo sapiens
324 MAPK6  
Affinity Capture-MS Homo sapiens
325 ACTR5 79913
Affinity Capture-MS Homo sapiens
326 RBM14-RBM4 100526737
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
327 USP19 10869
Affinity Capture-Western Homo sapiens
328 FSCN1 6624
Affinity Capture-MS Homo sapiens
329 UBXN1 51035
Affinity Capture-MS Homo sapiens
330 ATP2B3 492
Affinity Capture-MS Homo sapiens
331 BKRF1  
Affinity Capture-MS
332 TUBG1 7283
Affinity Capture-MS Homo sapiens
333 VPS52 6293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 SMURF1 57154
Biochemical Activity Homo sapiens
335 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
Reconstituted Complex Homo sapiens
336 SUCLA2 8803
Affinity Capture-MS Homo sapiens
337 UBB 7314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 MAGED1 9500
Affinity Capture-MS Homo sapiens
339 SLC25A4 291
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
340 SEC62 7095
Proximity Label-MS Homo sapiens
341 C19orf52  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 DNAJC1 64215
Proximity Label-MS Homo sapiens
343 C9orf72  
Affinity Capture-MS Homo sapiens
344 ESYT1 23344
Affinity Capture-MS Homo sapiens
345 ECSIT 51295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here