Gene description for TMEM159
Gene name transmembrane protein 159
Gene symbol TMEM159
Other names/aliases -
Species Homo sapiens
 Database cross references - TMEM159
ExoCarta ExoCarta_57146
Vesiclepedia VP_57146
Entrez Gene 57146
HGNC 30136
MIM 611304
UniProt Q96B96  
 TMEM159 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TMEM159
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    lipid droplet formation GO:0140042 IMP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IDA
    lipid droplet GO:0005811 IDA
 Experiment description of studies that identified TMEM159 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TMEM159
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CCDC12  
Affinity Capture-MS Homo sapiens
2 ZNF391  
Two-hybrid Homo sapiens
3 HSD17B11 51170
Proximity Label-MS Homo sapiens
4 TSPAN16  
Affinity Capture-MS Homo sapiens
5 C4orf32  
Affinity Capture-MS Homo sapiens
6 FAF2 23197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 GAD2  
Two-hybrid Homo sapiens
8 RTN2 6253
Affinity Capture-MS Homo sapiens
9 SLC35G1  
Affinity Capture-MS Homo sapiens
10 ADCK3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 METTL7A 25840
Proximity Label-MS Homo sapiens
12 RAB1B 81876
Affinity Capture-MS Homo sapiens
13 RTP2  
Affinity Capture-MS Homo sapiens
14 RFWD2  
Affinity Capture-MS Homo sapiens
15 SLC44A1 23446
Affinity Capture-MS Homo sapiens
16 MLYCD 23417
Affinity Capture-MS Homo sapiens
17 BSCL2  
Affinity Capture-MS Homo sapiens
18 HSD3B7 80270
Proximity Label-MS Homo sapiens
19 ENDOD1 23052
Affinity Capture-MS Homo sapiens
20 EGFR 1956
Affinity Capture-MS Homo sapiens
21 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
22 SLC19A2 10560
Affinity Capture-MS Homo sapiens
23 OBFC1 79991
Affinity Capture-MS Homo sapiens
24 RAB14 51552
Affinity Capture-MS Homo sapiens
25 RAB2B 84932
Affinity Capture-MS Homo sapiens
26 MTMR9 66036
Affinity Capture-MS Homo sapiens
27 AUP1 550
Affinity Capture-MS Homo sapiens
28 GIMAP2  
Affinity Capture-MS Homo sapiens
29 IL17F  
Affinity Capture-MS Homo sapiens
30 TM2D3  
Affinity Capture-MS Homo sapiens
31 MB21D2  
Affinity Capture-MS Homo sapiens
32 SEC61B 10952
Proximity Label-MS Homo sapiens
33 SEC62 7095
Proximity Label-MS Homo sapiens
34 USE1 55850
Affinity Capture-MS Homo sapiens
35 CACFD1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 CYB5R3 1727
Affinity Capture-MS Homo sapiens
37 ZNF518A 9849
Affinity Capture-MS Homo sapiens
38 RAB5C 5878
Proximity Label-MS Homo sapiens
39 WBSCR28 135886
Affinity Capture-MS Homo sapiens
40 CC2D1A 54862
Affinity Capture-MS Homo sapiens
41 RNF26  
Affinity Capture-MS Homo sapiens
42 CLEC14A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CTC1  
Affinity Capture-MS Homo sapiens
44 C3orf52  
Affinity Capture-MS Homo sapiens
45 ACBD5 91452
Proximity Label-MS Homo sapiens
46 MTMR6 9107
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TMEM159 is involved
No pathways found





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