Gene description for VCPIP1
Gene name
valosin containing protein (p97)/p47 complex interacting protein 1
Gene symbol
VCPIP1
Other names/aliases
DUBA3 VCIP135
Species
Homo sapiens
Database cross references - VCPIP1
ExoCarta
ExoCarta_80124
Entrez Gene
80124
HGNC
30897
MIM
611745
UniProt
Q96JH7
VCPIP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Thymus
23844026
Gene ontology annotations for VCPIP1
Experiment description of studies that identified VCPIP1 in exosomes
1
Experiment ID
235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for VCPIP1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
NSFL1C
55968
Invivo
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Invitro
Homo sapiens
2
VCP
7415
Invivo
Homo sapiens
Invitro
Homo sapiens
3
STX5A
Invitro
Homo sapiens
Invivo
Homo sapiens
View the network
image/svg+xml
Pathways in which VCPIP1 is involved
No pathways found