Gene description for KCTD14
Gene name potassium channel tetramerization domain containing 14
Gene symbol KCTD14
Other names/aliases -
Species Homo sapiens
 Database cross references - KCTD14
ExoCarta ExoCarta_65987
Vesiclepedia VP_65987
Entrez Gene 65987
HGNC 23295
UniProt Q9BQ13  
 KCTD14 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 25890246    
 Gene ontology annotations for KCTD14
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein homooligomerization GO:0051260 IEA
 Experiment description of studies that identified KCTD14 in exosomes
1
Experiment ID 283
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KCTD14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ACSF3 197322
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 KCTD14 65987
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 ABCF3 55324
Affinity Capture-MS Homo sapiens
4 DNAAF5 54919
Affinity Capture-MS Homo sapiens
5 DHFR 1719
Affinity Capture-MS Homo sapiens
6 ANKS1A 23294
Affinity Capture-MS Homo sapiens
7 PDXDC1 23042
Affinity Capture-MS Homo sapiens
8 IKBKB 3551
Affinity Capture-MS Homo sapiens
9 COASY 80347
Affinity Capture-MS Homo sapiens
10 STK16 8576
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 VCPIP1 80124
Affinity Capture-MS Homo sapiens
12 OXSR1 9943
Affinity Capture-MS Homo sapiens
13 CHUK 1147
Affinity Capture-MS Homo sapiens
14 TCF4  
Two-hybrid Homo sapiens
15 UBXN6 80700
Affinity Capture-MS Homo sapiens
16 TUBGCP6 85378
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 PMVK 10654
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KCTD14 is involved
No pathways found





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