Gene description for HSPA6
Gene name heat shock 70kDa protein 6 (HSP70B')
Gene symbol HSPA6
Other names/aliases -
Species Homo sapiens
 Database cross references - HSPA6
ExoCarta ExoCarta_3310
Vesiclepedia VP_3310
Entrez Gene 3310
HGNC 5239
MIM 140555
UniProt P17066  
 HSPA6 identified in exosomes derived from the following tissue/cell type
Bladder cancer cells 20224111    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Urine 15326289    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for HSPA6
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IBA
    ATP hydrolysis activity GO:0016887 IDA
    enzyme binding GO:0019899 IPI
    heat shock protein binding GO:0031072 IBA
    heat shock protein binding GO:0031072 IPI
    protein folding chaperone GO:0044183 IBA
    unfolded protein binding GO:0051082 IDA
    ATP-dependent protein folding chaperone GO:0140662 IEA
Biological Process
    response to unfolded protein GO:0006986 TAS
    cellular response to heat GO:0034605 IDA
    cellular response to heat GO:0034605 IMP
    protein refolding GO:0042026 IBA
    protein refolding GO:0042026 IDA
    chaperone cofactor-dependent protein refolding GO:0051085 IBA
    cellular heat acclimation GO:0070370 IMP
Subcellular Localization
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    centriole GO:0005814 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IBA
    COP9 signalosome GO:0008180 IDA
    secretory granule lumen GO:0034774 TAS
    extracellular exosome GO:0070062 HDA
    blood microparticle GO:0072562 HDA
    ficolin-1-rich granule lumen GO:1904813 TAS
 Experiment description of studies that identified HSPA6 in exosomes
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A.
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
3
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
4
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors Hosseini-Beheshti E, Guns ES.
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
11
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors Hosseini-Beheshti E, Guns ES.
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
12
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
15
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors Pisitkun T, Shen RF, Knepper MA
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
16
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSPA6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Co-fractionation Homo sapiens
2 PRODH  
Affinity Capture-MS Homo sapiens
3 WDR6 11180
Co-fractionation Homo sapiens
4 UBL4A 8266
Affinity Capture-MS Homo sapiens
5 QARS 5859
Co-fractionation Homo sapiens
6 SHC1 6464
Affinity Capture-MS Homo sapiens
7 CCNI2  
Affinity Capture-MS Homo sapiens
8 SKI 6497
Affinity Capture-MS Homo sapiens
9 CYP4F12  
Two-hybrid Homo sapiens
10 PARD3 56288
Affinity Capture-MS Homo sapiens
11 CRK 1398
Affinity Capture-MS Homo sapiens
12 DNAJA4 55466
Affinity Capture-Western Homo sapiens
13 CAP1 10487
Co-fractionation Homo sapiens
14 DNAJB2 3300
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 UBA1 7317
Co-fractionation Homo sapiens
16 HSPA1L 3305
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
17 PLEKHF2 79666
Co-fractionation Homo sapiens
18 MICALL1 85377
Co-fractionation Homo sapiens
19 NTNG1  
Affinity Capture-MS Homo sapiens
20 HSP90AB1 3326
Co-fractionation Homo sapiens
21 BASP1 10409
Co-fractionation Homo sapiens
22 TROVE2 6738
Co-fractionation Homo sapiens
23 DNAJB3 414061
Affinity Capture-MS Homo sapiens
24 RPS6KB2  
Affinity Capture-MS Homo sapiens
25 TTC30B  
Affinity Capture-MS Homo sapiens
26 RFFL 117584
Affinity Capture-MS Homo sapiens
27 TMPO 7112
Affinity Capture-MS Homo sapiens
28 DNAJB6 10049
Affinity Capture-Western Homo sapiens
29 GBA 2629
Affinity Capture-MS Homo sapiens
30 ZNF488  
Affinity Capture-MS Homo sapiens
31 NDRG2 57447
Affinity Capture-MS Homo sapiens
32 GPS1 2873
Co-fractionation Homo sapiens
33 PRDX3 10935
Co-fractionation Homo sapiens
34 HSPA2 3306
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
35 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
36 MCM2 4171
Affinity Capture-MS Homo sapiens
37 ABHD15  
Affinity Capture-MS Homo sapiens
38 COPS6 10980
Co-fractionation Homo sapiens
39 TLN1 7094
Co-fractionation Homo sapiens
40 COPS5 10987
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
41 FLNA 2316
Two-hybrid Homo sapiens
42 EPB41L2 2037
Co-fractionation Homo sapiens
43 TRABD 80305
Affinity Capture-MS Homo sapiens
44 MLST8 64223
Affinity Capture-MS Homo sapiens
45 DNAJB1 3337
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
46 KIAA1191  
Affinity Capture-MS Homo sapiens
47 TSSK1B  
Affinity Capture-MS Homo sapiens
48 ACLY 47
Co-fractionation Homo sapiens
49 SLX4  
Affinity Capture-MS Homo sapiens
50 GART 2618
Co-fractionation Homo sapiens
51 DNAJC7 7266
Proximity Label-MS Homo sapiens
52 CLTC 1213
Proximity Label-MS Homo sapiens
53 VASH1  
Affinity Capture-MS Homo sapiens
54 RSG1  
Affinity Capture-MS Homo sapiens
55 MECP2 4204
Affinity Capture-MS Homo sapiens
56 CUL1 8454
Affinity Capture-MS Homo sapiens
57 TFCP2 7024
Affinity Capture-MS Homo sapiens
58 KNSTRN  
Affinity Capture-MS Homo sapiens
59 KBTBD4  
Affinity Capture-MS Homo sapiens
60 FGFR1 2260
Affinity Capture-MS Homo sapiens
61 PABPC4 8761
Co-fractionation Homo sapiens
62 DNAJB7  
Affinity Capture-Western Homo sapiens
63 HSPA8 3312
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
64 INSIG2  
Affinity Capture-MS Homo sapiens
65 RFPL2  
Affinity Capture-MS Homo sapiens
66 STOML2 30968
Co-fractionation Homo sapiens
67 HSPBP1 23640
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 PRAP1  
Two-hybrid Homo sapiens
69 VRK3 51231
Affinity Capture-MS Homo sapiens
70 PPIB 5479
Two-hybrid Homo sapiens
71 SCFD1 23256
Co-fractionation Homo sapiens
72 PLCG1 5335
Co-fractionation Homo sapiens
73 PPP5C 5536
Affinity Capture-MS Homo sapiens
74 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
75 DNAJB8  
Affinity Capture-Western Homo sapiens
76 NCKIPSD 51517
Co-fractionation Homo sapiens
77 GAL  
Affinity Capture-MS Homo sapiens
78 MEPCE 56257
Affinity Capture-MS Homo sapiens
79 KLHL34  
Affinity Capture-MS Homo sapiens
80 CBL 867
Affinity Capture-MS Homo sapiens
81 CAST 831
Co-fractionation Homo sapiens
82 POC1A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 C22orf15  
Two-hybrid Homo sapiens
84 PABPC1 26986
Co-fractionation Homo sapiens
85 DYNLL1 8655
Co-fractionation Homo sapiens
86 Sidt2  
Affinity Capture-MS Mus musculus
87 YAP1 10413
Affinity Capture-MS Homo sapiens
88 MYH9 4627
Co-fractionation Homo sapiens
89 RAN 5901
Co-fractionation Homo sapiens
90 TRIM21 6737
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 NTRK1 4914
Affinity Capture-MS Homo sapiens
92 VPRBP 9730
Co-fractionation Homo sapiens
93 SYNCRIP 10492
Co-fractionation Homo sapiens
94 NXF5  
Affinity Capture-MS Homo sapiens
95 LRRC8E 80131
Affinity Capture-MS Homo sapiens
96 F12  
Affinity Capture-MS Homo sapiens
97 NOS2  
Affinity Capture-MS Homo sapiens
98 FLNB 2317
Co-fractionation Homo sapiens
99 COPS3 8533
Co-fractionation Homo sapiens
100 HNRNPL 3191
Co-fractionation Homo sapiens
101 COPS7B 64708
Co-fractionation Homo sapiens
102 VCPIP1 80124
Co-fractionation Homo sapiens
103 MLF2 8079
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
104 DNAJC13 23317
Proximity Label-MS Homo sapiens
105 Ksr1  
Affinity Capture-MS Mus musculus
106 CYLD  
Affinity Capture-MS Homo sapiens
107 DNAJB11 51726
Affinity Capture-MS Homo sapiens
108 ADCK5  
Two-hybrid Homo sapiens
109 PXN 5829
Co-fractionation Homo sapiens
110 BAG3 9531
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
111 HNRNPD 3184
Affinity Capture-MS Homo sapiens
112 GAN 8139
Affinity Capture-MS Homo sapiens
113 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
114 COPS2 9318
Co-fractionation Homo sapiens
115 FRMD8P1  
Affinity Capture-MS Homo sapiens
116 FANCD2  
Affinity Capture-MS Homo sapiens
117 TRIM31  
Affinity Capture-MS Homo sapiens
118 COPS7A 50813
Co-fractionation Homo sapiens
119 AHCYL1 10768
Two-hybrid Homo sapiens
120 BAG1 573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 RC3H2  
Affinity Capture-MS Homo sapiens
122 YBX1 4904
Co-fractionation Homo sapiens
123 ATP5A1 498
Co-fractionation Homo sapiens
124 TRAF3IP1 26146
Affinity Capture-MS Homo sapiens
125 IQCB1  
Affinity Capture-MS Homo sapiens
126 COPS8 10920
Co-fractionation Homo sapiens
127 NUP43 348995
Proximity Label-MS Homo sapiens
128 SNX27 81609
Affinity Capture-MS Homo sapiens
129 RIPK4  
Affinity Capture-MS Homo sapiens
130 LARS 51520
Co-fractionation Homo sapiens
131 DNAJA1 3301
Affinity Capture-Western Homo sapiens
132 Paxip1  
Affinity Capture-MS Mus musculus
133 AP2M1 1173
Affinity Capture-MS Homo sapiens
134 SGTB  
Affinity Capture-MS Homo sapiens
135 DHRS13  
Affinity Capture-MS Homo sapiens
136 MYO1D 4642
Affinity Capture-MS Homo sapiens
137 UBASH3A 53347
Affinity Capture-MS Homo sapiens
138 GNB2 2783
Affinity Capture-MS Homo sapiens
139 COMMD6 170622
Two-hybrid Homo sapiens
140 C14orf80  
Affinity Capture-MS Homo sapiens
141 LGALS7B 653499
Two-hybrid Homo sapiens
142 HSPA1A 3303
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
143 RPAP3 79657
Affinity Capture-MS Homo sapiens
144 HSPA4 3308
Affinity Capture-MS Homo sapiens
145 CDK20  
Affinity Capture-MS Homo sapiens
146 DYRK2 8445
Affinity Capture-MS Homo sapiens
147 LIME1 54923
Affinity Capture-MS Homo sapiens
148 ILK 3611
Affinity Capture-MS Homo sapiens
149 PELI3  
Affinity Capture-MS Homo sapiens
150 STYX  
Affinity Capture-MS Homo sapiens
151 HSPD1 3329
Co-fractionation Homo sapiens
152 LGALS7 3963
Two-hybrid Homo sapiens
153 HSPA9 3313
Co-fractionation Homo sapiens
154 KRT222 125113
Two-hybrid Homo sapiens
155 C9orf72  
Affinity Capture-MS Homo sapiens
156 BAG4  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
157 DSP 1832
Co-fractionation Homo sapiens
158 MOCS3 27304
Affinity Capture-MS Homo sapiens
159 DHX15 1665
Co-fractionation Homo sapiens
160 ARRB2 409
Affinity Capture-MS Homo sapiens
161 FASN 2194
Co-fractionation Homo sapiens
162 ALDH3A2 224
Proximity Label-MS Homo sapiens
163 GRB2 2885
Co-fractionation Homo sapiens
164 FBXL6  
Affinity Capture-MS Homo sapiens
165 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 FOLR1 2348
Affinity Capture-MS Homo sapiens
167 INPPL1 3636
Affinity Capture-MS Homo sapiens
168 RFWD2  
Affinity Capture-MS Homo sapiens
169 DNAJA2 10294
Affinity Capture-Western Homo sapiens
170 MCM5 4174
Affinity Capture-MS Homo sapiens
171 RPA1 6117
Two-hybrid Homo sapiens
172 CCDC117  
Affinity Capture-MS Homo sapiens
173 PNPLA5  
Affinity Capture-MS Homo sapiens
174 DNAJB5  
Affinity Capture-Western Homo sapiens
175 PLOD1 5351
Co-fractionation Homo sapiens
176 FAM83F 113828
Affinity Capture-MS Homo sapiens
177 OTUB1 55611
Affinity Capture-MS Homo sapiens
178 NUP35 129401
Proximity Label-MS Homo sapiens
179 SSBP1 6742
Co-fractionation Homo sapiens
180 RNF7  
Co-fractionation Homo sapiens
181 TLR9  
Affinity Capture-MS Homo sapiens
182 GSTM3 2947
Co-fractionation Homo sapiens
183 AGBL4  
Affinity Capture-MS Homo sapiens
184 TERF1 7013
Two-hybrid Homo sapiens
185 BAG5 9529
Affinity Capture-MS Homo sapiens
186 GAPDH 2597
Co-fractionation Homo sapiens
187 C3orf38 285237
Affinity Capture-MS Homo sapiens
188 SUPT6H 6830
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
189 EIF4B 1975
Affinity Capture-MS Homo sapiens
190 PSMA7 5688
Co-fractionation Homo sapiens
191 DNAJB4 11080
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
192 CDK9 1025
Affinity Capture-MS Homo sapiens
193 PINK1  
Affinity Capture-MS Homo sapiens
194 CLTA 1211
Proximity Label-MS Homo sapiens
195 CISH  
Two-hybrid Homo sapiens
196 DOCK7 85440
Co-fractionation Homo sapiens
197 SERBP1 26135
Affinity Capture-MS Homo sapiens
198 PIK3R2 5296
Affinity Capture-MS Homo sapiens
199 SNW1 22938
Co-fractionation Homo sapiens
200 NR1I3  
Affinity Capture-MS Homo sapiens
201 LRRC28  
Affinity Capture-MS Homo sapiens
202 PSMB2 5690
Affinity Capture-Western Homo sapiens
203 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 ATXN3 4287
Affinity Capture-MS Homo sapiens
205 COPS4 51138
Co-fractionation Homo sapiens
206 FBXO38 81545
Proximity Label-MS Homo sapiens
207 ODF3L1  
Affinity Capture-MS Homo sapiens
208 EEF2 1938
Co-fractionation Homo sapiens
209 NEDD8 4738
Affinity Capture-MS Homo sapiens
210 CDC5L 988
Affinity Capture-MS Homo sapiens
211 VILL  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here