Gene description for UBASH3A
Gene name ubiquitin associated and SH3 domain containing A
Gene symbol UBASH3A
Other names/aliases CLIP4
STS-2
TULA
TULA-1
Species Homo sapiens
 Database cross references - UBASH3A
ExoCarta ExoCarta_53347
Vesiclepedia VP_53347
Entrez Gene 53347
HGNC 12462
MIM 605736
UniProt P57075  
 UBASH3A identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for UBASH3A
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    regulation of cytokine production GO:0001817 IEA
    negative regulation of T cell receptor signaling pathway GO:0050860 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 HDA
    cytosol GO:0005829 IDA
    nuclear speck GO:0016607 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified UBASH3A in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UBASH3A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CBS 875
Two-hybrid Homo sapiens
2 HSPA6 3310
Affinity Capture-MS Homo sapiens
3 REL 5966
Two-hybrid Homo sapiens
4 SH3RF1  
Two-hybrid Homo sapiens
5 GFAP 2670
Two-hybrid Homo sapiens
6 TUBB8 347688
Reconstituted Complex Homo sapiens
7 TEKT1  
Two-hybrid Homo sapiens
8 UBC 7316
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
9 N4BP3  
Two-hybrid Homo sapiens
10 STX11 8676
Two-hybrid Homo sapiens
11 CD247 919
Affinity Capture-Western Homo sapiens
12 MYEOV2 150678
Two-hybrid Homo sapiens
13 DTX3  
Two-hybrid Homo sapiens
14 ZAP70 7535
Affinity Capture-Western Homo sapiens
15 TRIM50  
Two-hybrid Homo sapiens
16 KRT40  
Two-hybrid Homo sapiens
17 CD3E 916
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
18 ABCE1 6059
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
19 HSP90B1 7184
Reconstituted Complex Homo sapiens
20 SNRNP48  
Two-hybrid Homo sapiens
21 ALK 238
Affinity Capture-MS Homo sapiens
22 KPRP 448834
Two-hybrid Homo sapiens
23 WASL 8976
Two-hybrid Homo sapiens
24 ZNF219  
Two-hybrid Homo sapiens
25 DNM1 1759
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
26 CBLB 868
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
27 BCAR3 8412
Two-hybrid Homo sapiens
28 TRIM8  
Two-hybrid Homo sapiens
29 GOLGA6L9  
Two-hybrid Homo sapiens
30 PMEPA1 56937
Two-hybrid Homo sapiens
31 TMCO2  
Two-hybrid Homo sapiens
32 RNF41  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
33 KRT39  
Two-hybrid Homo sapiens
34 ARRDC1 92714
Two-hybrid Homo sapiens
35 PARK2  
Reconstituted Complex Homo sapiens
36 CCDC33 80125
Two-hybrid Homo sapiens
37 PSMC1 5700
Reconstituted Complex Homo sapiens
38 CBL 867
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
39 PNMA5 114824
Two-hybrid Homo sapiens
40 DAZAP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
41 PLEKHB2 55041
Two-hybrid Homo sapiens
42 UBASH3B 84959
Affinity Capture-MS Homo sapiens
43 NSMF  
Two-hybrid Homo sapiens
44 VCP 7415
Reconstituted Complex Homo sapiens
45 CRK 1398
Affinity Capture-MS Homo sapiens
46 TMEM239  
Two-hybrid Homo sapiens
47 KRT14 3861
Two-hybrid Homo sapiens
48 ARRDC3 57561
Two-hybrid Homo sapiens
49 ACTB 60
Affinity Capture-MS Homo sapiens
50 ZNF474  
Two-hybrid Homo sapiens
51 VPS37B 79720
Two-hybrid Homo sapiens
52 DISC1 27185
Two-hybrid Homo sapiens
53 C9orf24  
Two-hybrid Homo sapiens
54 AIFM1 9131
Affinity Capture-Western Homo sapiens
55 TAX1BP1 8887
Two-hybrid Homo sapiens
56 KRT35 3886
Two-hybrid Homo sapiens
57 KRT32  
Two-hybrid Homo sapiens
58 UBE2L3 7332
FRET Homo sapiens
59 TEKT4  
Two-hybrid Homo sapiens
60 EGFR 1956
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
61 LZTS2 84445
Two-hybrid Homo sapiens
62 MKRN1 23608
Two-hybrid Homo sapiens
63 UBLCP1  
Affinity Capture-MS Homo sapiens
64 UBASH3A 53347
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
65 TRIM5 85363
Two-hybrid Homo sapiens
66 SPRY1 10252
Two-hybrid Homo sapiens
67 TRIM27  
Two-hybrid Homo sapiens
68 HSPA1A 3303
Affinity Capture-MS Homo sapiens
69 HSPA4 3308
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
70 HIP1 3092
Affinity Capture-MS Homo sapiens
71 HSPD1 3329
Reconstituted Complex Homo sapiens
72 ZC2HC1C  
Two-hybrid Homo sapiens
73 ISY1-RAB43 100534599
Two-hybrid Homo sapiens
74 KCNE1  
Two-hybrid Homo sapiens
75 SLA2 84174
Two-hybrid Homo sapiens
76 TP53BP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
77 SPRY2 10253
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
78 SHISA6  
Two-hybrid Homo sapiens
79 SF3B4 10262
Two-hybrid Homo sapiens
80 SOS1 6654
Two-hybrid Homo sapiens
81 HSP90AA1 3320
Reconstituted Complex Homo sapiens
82 DDIT4L  
Two-hybrid Homo sapiens
83 TRIM37  
Two-hybrid Homo sapiens
84 FGFR1OP2  
Two-hybrid Homo sapiens
85 FAM83A  
Two-hybrid Homo sapiens
86 KCTD1 284252
Two-hybrid Homo sapiens
87 LCN2 3934
Two-hybrid Homo sapiens
88 ZBTB42  
Two-hybrid Homo sapiens
89 PSMC4 5704
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
90 FADS6  
Two-hybrid Homo sapiens
91 KIAA0408  
Two-hybrid Homo sapiens
92 TIMM44 10469
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which UBASH3A is involved
No pathways found





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