Gene description for UBE2L3
Gene name	ubiquitin-conjugating enzyme E2L 3
Gene symbol	UBE2L3
Other names/aliases	E2-F1 L-UBC UBCH7 UbcM4
Species	Homo sapiens
Database cross references - UBE2L3
ExoCarta	ExoCarta_7332
Entrez Gene	7332
HGNC	12488
MIM	603721
UniProt	P68036
UBE2L3 identified in exosomes derived from the following tissue/cell type
Melanoma cells	25950383
Melanoma cells	25950383
Melanoma cells	25950383
Prostate cancer cells	25844599
Squamous carcinoma cells	20124223

Gene ontology annotations for UBE2L3

Molecular Function     protein binding GO:0005515 IPI     ubiquitin-protein transferase activity GO:0004842 TAS     ligase activity GO:0016874 IEA     enzyme binding GO:0019899 TAS     ubiquitin conjugating enzyme activity GO:0061631 IDA     ATP binding GO:0005524 IEA     poly(A) RNA binding GO:0044822 IDA     ubiquitin-protein transferase activator activity GO:0097027 IGI     ubiquitin protein ligase binding GO:0031625 IPI     transcription coactivator activity GO:0003713 IDA Biological Process     transcription, DNA-templated GO:0006351 IEA     positive regulation of ubiquitin-protein transferase activity GO:0051443 IGI     cell proliferation GO:0008283 IMP     cellular response to steroid hormone stimulus GO:0071383 IMP     protein ubiquitination GO:0016567 IDA     positive regulation of protein targeting to mitochondrion GO:1903955 IMP     cell cycle phase transition GO:0044770 IMP     cellular response to glucocorticoid stimulus GO:0071385 IDA     ubiquitin-dependent protein catabolic process GO:0006511 TAS     protein polyubiquitination GO:0000209 IDA     cellular protein modification process GO:0006464 TAS     regulation of transcription, DNA-templated GO:0006355 IMP     positive regulation of protein ubiquitination GO:0031398 IGI     protein K11-linked ubiquitination GO:0070979 IDA Subcellular Localization     nucleus GO:0005634 IDA     ubiquitin ligase complex GO:0000151 TAS     cytoplasm GO:0005737 IDA     extracellular exosome GO:0070062 IDA