Gene description for DUSP4
Gene name	dual specificity phosphatase 4
Gene symbol	DUSP4
Other names/aliases	HVH2 MKP-2 MKP2 TYP
Species	Homo sapiens
Database cross references - DUSP4
ExoCarta	ExoCarta_1846
Entrez Gene	1846
HGNC	3070
MIM	602747
UniProt	Q13115
DUSP4 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for DUSP4

Molecular Function     protein tyrosine/serine/threonine phosphatase activity GO:0008138 IBA     MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 IEA     protein tyrosine/threonine phosphatase activity GO:0008330 TAS     protein tyrosine phosphatase activity GO:0004725 IEA Biological Process     toll-like receptor 5 signaling pathway GO:0034146 TAS     toll-like receptor 2 signaling pathway GO:0034134 TAS     inactivation of MAPK activity GO:0000188 IEA     toll-like receptor 9 signaling pathway GO:0034162 TAS     MAPK cascade GO:0000165 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     toll-like receptor signaling pathway GO:0002224 TAS     protein dephosphorylation GO:0006470 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     peptidyl-tyrosine dephosphorylation GO:0035335 IEA     innate immune response GO:0045087 TAS     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     stress-activated MAPK cascade GO:0051403 TAS     endoderm formation GO:0001706 IBA     toll-like receptor 10 signaling pathway GO:0034166 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS Subcellular Localization     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 TAS