Gene description for NME2P1
Gene name NME/NM23 nucleoside diphosphate kinase 2 pseudogene 1
Gene symbol NME2P1
Other names/aliases -
Species Homo sapiens
 Database cross references - NME2P1
ExoCarta ExoCarta_283458
Entrez Gene 283458
HGNC 31358
 NME2P1 identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
 Gene ontology annotations for NME2P1
Molecular Function
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
    nucleoside diphosphate kinase activity GO:0004550 IEA
Biological Process
    CTP biosynthetic process GO:0006241 IEA
    nucleoside diphosphate phosphorylation GO:0006165 IEA
    UTP biosynthetic process GO:0006228 IEA
    GTP biosynthetic process GO:0006183 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified NME2P1 in exosomes
1
Experiment ID 260
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1|CD81
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for NME2P1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NME2P1 is involved
No pathways found





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