Gene description for P2RY12
Gene name	purinergic receptor P2Y, G-protein coupled, 12
Gene symbol	P2RY12
Other names/aliases	ADPG-R BDPLT8 HORK3 P2T(AC) P2Y(12)R P2Y(AC) P2Y(ADP) P2Y(cyc) P2Y12 SP1999
Species	Homo sapiens
Database cross references - P2RY12
ExoCarta	ExoCarta_64805
Entrez Gene	64805
HGNC	18124
MIM	600515
UniProt	Q9H244
P2RY12 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for P2RY12

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 TAS     ADP receptor activity GO:0001621 IMP     G-protein coupled adenosine receptor activity GO:0001609 IEA Biological Process     positive regulation of GTPase activity GO:0043547 TAS     adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway GO:0007193 IMP     negative regulation of cell differentiation GO:0045596 IEA     calcium ion transmembrane transport GO:0070588 IEA     negative regulation of norepinephrine secretion GO:0010700 IEA     hemostasis GO:0007599 NAS     platelet activation GO:0030168 TAS     G-protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 IMP     platelet aggregation GO:0070527 IMP     G-protein coupled receptor signaling pathway GO:0007186 IDA     protein kinase B signaling GO:0043491 IEA     regulation of calcium ion transport GO:0051924 IEA     potassium ion transmembrane transport GO:0071805 IEA     adenosine receptor signaling pathway GO:0001973 IEA     positive regulation of ion transport GO:0043270 IEA     cell projection organization GO:0030030 IEA     blood coagulation GO:0007596 TAS Subcellular Localization     plasma membrane GO:0005886 TAS     mitochondrion GO:0005739 IEA     intrinsic component of membrane GO:0031224 IDA     integral component of plasma membrane GO:0005887 IBA     caveola GO:0005901 IEA     basal plasma membrane GO:0009925 IEA     cell surface GO:0009986 IDA     external side of plasma membrane GO:0009897 IEA