Gene description for BRI3BP |
Gene name |
BRI3 binding protein |
Gene symbol |
BRI3BP |
Other names/aliases |
BNAS1 HCCR-1 HCCR-2 HCCRBP-1 KG19 |
Species |
Homo sapiens |
Database cross references - BRI3BP |
ExoCarta |
ExoCarta_140707 |
Entrez Gene |
140707 |
HGNC |
14251 |
MIM |
615627 |
UniProt |
Q8WY22
|
BRI3BP identified in exosomes derived from the following tissue/cell type |
Colorectal cancer cells
|
17956143
|
Liver cancer cells
|
25265333
|
Liver cancer cells
|
25265333
|
Gene ontology annotations for BRI3BP |
|
Experiment description of studies that identified BRI3BP in exosomes |
1 |
Experiment ID |
20 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSP90
|
EV Cytosolic markers |
✔
CD63|CD81|LAMP1
|
EV Membrane markers |
✔
GOLGA2|cytochrome c
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17956143
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of microvesicles derived from human colorectal cancer cells. |
Authors |
Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS |
Journal name |
JPR
|
Publication year |
2007 |
Sample |
Colorectal cancer cells |
Sample name |
HT29 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density |
1.16 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LTQ] Western blotting |
|
|
2 |
Experiment ID |
266 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✔
CANX|HSP90B1
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25265333
|
Organism |
Homo sapiens |
Experiment description |
Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS |
Authors |
Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J |
Journal name |
J Proteome Res
|
Publication year |
2014 |
Sample |
Liver cancer cells |
Sample name |
Huh-7 - Wild type |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
3 |
Experiment ID |
268 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✔
CANX|HSP90B1
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25265333
|
Organism |
Homo sapiens |
Experiment description |
Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS |
Authors |
Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J |
Journal name |
J Proteome Res
|
Publication year |
2014 |
Sample |
Liver cancer cells |
Sample name |
Huh-7 - Transfected with HBx-null HBV replicon plasmids |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
Protein-protein interactions for BRI3BP |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which BRI3BP is involved |
No pathways found
|
|
|