Gene description for PTRHD1
Gene name peptidyl-tRNA hydrolase domain containing 1
Gene symbol PTRHD1
Other names/aliases C2orf79
Species Homo sapiens
 Database cross references - PTRHD1
ExoCarta ExoCarta_391356
Vesiclepedia VP_391356
Entrez Gene 391356
HGNC 33782
UniProt Q6GMV3  
 PTRHD1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PTRHD1
Molecular Function
    aminoacyl-tRNA hydrolase activity GO:0004045 IEA
    protein binding GO:0005515 IPI
Subcellular Localization
    mitochondrion GO:0005739 HTP
 Experiment description of studies that identified PTRHD1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PTRHD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZRANB1 54764
Affinity Capture-MS Homo sapiens
2 TXN2 25828
Co-fractionation Homo sapiens
3 TIAL1 7073
Co-fractionation Homo sapiens
4 COA4  
Co-fractionation Homo sapiens
5 AK2 204
Co-fractionation Homo sapiens
6 FABP3 2170
Co-fractionation Homo sapiens
7 ALDH4A1 8659
Co-fractionation Homo sapiens
8 GIMAP8 155038
Co-fractionation Homo sapiens
9 MSRB2  
Co-fractionation Homo sapiens
10 TRIAP1  
Co-fractionation Homo sapiens
11 S100A6 6277
Affinity Capture-MS Homo sapiens
12 UBE2L3 7332
Co-fractionation Homo sapiens
13 NFKBIA  
Affinity Capture-MS Homo sapiens
14 ANXA1 301
Co-fractionation Homo sapiens
15 PRDX5 25824
Co-fractionation Homo sapiens
16 FSD1  
Affinity Capture-MS Homo sapiens
17 LYPLAL1 127018
Co-fractionation Homo sapiens
18 FAHD1 81889
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
19 NUDT19 390916
Co-fractionation Homo sapiens
20 SHMT2 6472
Affinity Capture-RNA Homo sapiens
21 AK1 203
Co-fractionation Homo sapiens
22 CARS2 79587
Co-fractionation Homo sapiens
23 TXN 7295
Co-fractionation Homo sapiens
24 IDH2 3418
Co-fractionation Homo sapiens
25 MOV10 4343
Affinity Capture-RNA Homo sapiens
26 ABHD11 83451
Co-fractionation Homo sapiens
27 PRDX6 9588
Co-fractionation Homo sapiens
28 GSX1  
Affinity Capture-MS Homo sapiens
29 SPR 6697
Co-fractionation Homo sapiens
30 MSRB3 253827
Co-fractionation Homo sapiens
31 AK3 50808
Co-fractionation Homo sapiens
32 RPA4  
Two-hybrid Homo sapiens
33 P2RY12 64805
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 SUMO1P1  
Affinity Capture-MS Homo sapiens
35 LYPLA1 10434
Co-fractionation Homo sapiens
36 HINT1 3094
Co-fractionation Homo sapiens
37 C6orf89  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 TSR2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which PTRHD1 is involved
No pathways found





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