Gene description for NUDT19
Gene name nudix (nucleoside diphosphate linked moiety X)-type motif 19
Gene symbol NUDT19
Other names/aliases RP2
Species Homo sapiens
 Database cross references - NUDT19
ExoCarta ExoCarta_390916
Vesiclepedia VP_390916
Entrez Gene 390916
HGNC 32036
UniProt A8MXV4  
 NUDT19 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NUDT19
Molecular Function
    magnesium ion binding GO:0000287 ISS
    coenzyme A diphosphatase activity GO:0010945 TAS
Biological Process
    fatty acid catabolic process GO:0009062 TAS
    coenzyme A catabolic process GO:0015938 ISS
    medium-chain fatty-acyl-CoA catabolic process GO:0036114 ISS
    butyryl-CoA catabolic process GO:0044580 ISS
    succinyl-CoA catabolic process GO:1901289 ISS
    propionyl-CoA metabolic process GO:1902858 ISS
    malonyl-CoA catabolic process GO:2001294 ISS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    peroxisomal matrix GO:0005782 TAS
    cytosol GO:0005829 TAS
 Experiment description of studies that identified NUDT19 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NUDT19
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 NPC2 10577
Co-fractionation Homo sapiens
3 TXN2 25828
Co-fractionation Homo sapiens
4 GUK1 2987
Co-fractionation Homo sapiens
5 OXLD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 SQSTM1 8878
Proximity Label-MS Homo sapiens
7 TRUB2  
Proximity Label-MS Homo sapiens
8 GFAP 2670
Proximity Label-MS Homo sapiens
9 MTG2  
Proximity Label-MS Homo sapiens
10 BPNT1 10380
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 RPUSD4 84881
Proximity Label-MS Homo sapiens
12 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
13 CCDC90B  
Proximity Label-MS Homo sapiens
14 CRYZ 1429
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
15 PMPCA 23203
Proximity Label-MS Homo sapiens
16 HINT2 84681
Proximity Label-MS Homo sapiens
17 PTRHD1 391356
Co-fractionation Homo sapiens
18 DEFA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 NIT1 4817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 AK3 50808
Co-fractionation Homo sapiens
21 MRPS24 64951
Affinity Capture-MS Homo sapiens
22 FXN  
Co-fractionation Homo sapiens
23 SURF1  
Proximity Label-MS Homo sapiens
24 EXD2  
Proximity Label-MS Homo sapiens
25 DNAJC7 7266
Proximity Label-MS Homo sapiens
26 POLR2C 5432
Proximity Label-MS Homo sapiens
27 GIMAP8 155038
Co-fractionation Homo sapiens
28 LAMTOR1 55004
Proximity Label-MS Homo sapiens
29 TCOF1 6949
Co-fractionation Homo sapiens
30 MTCH2 23788
Proximity Label-MS Homo sapiens
31 PRDX5 25824
Co-fractionation Homo sapiens
32 ACSM5 54988
Affinity Capture-MS Homo sapiens
33 FASTKD5  
Proximity Label-MS Homo sapiens
34 PRPH 5630
Proximity Label-MS Homo sapiens
35 PARK2  
Affinity Capture-MS Homo sapiens
36 PPIL1 51645
Co-fractionation Homo sapiens
37 AKR1C3 8644
Co-fractionation Homo sapiens
38 BROX 148362
Co-fractionation Homo sapiens
39 TUFM 7284
Proximity Label-MS Homo sapiens
40 MYDGF 56005
Co-fractionation Homo sapiens
41 RFK 55312
Co-fractionation Homo sapiens
42 ACSM3  
Affinity Capture-MS Homo sapiens
43 MRPL11 65003
Proximity Label-MS Homo sapiens
44 MTRF1L  
Proximity Label-MS Homo sapiens
45 AGPS 8540
Proximity Label-MS Homo sapiens
46 DNAJC12  
Proximity Label-MS Homo sapiens
47 CSTB 1476
Co-fractionation Homo sapiens
48 SQRDL 58472
Co-fractionation Homo sapiens
49 ADH5 128
Co-fractionation Homo sapiens
50 OTC 5009
Proximity Label-MS Homo sapiens
51 WBSCR16  
Affinity Capture-MS Homo sapiens
52 AK2 204
Co-fractionation Homo sapiens
53 AK4 205
Co-fractionation Homo sapiens
54 AIFM1 9131
Proximity Label-MS Homo sapiens
55 MRPS12  
Proximity Label-MS Homo sapiens
56 MTIF2 4528
Proximity Label-MS Homo sapiens
57 HSD3B7 80270
Proximity Label-MS Homo sapiens
58 SLC9A3R2 9351
Co-fractionation Homo sapiens
59 SLC25A41  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 C12orf65  
Proximity Label-MS Homo sapiens
61 FABP5 2171
Co-fractionation Homo sapiens
62 RPA3 6119
Proximity Label-MS Homo sapiens
63 ARRDC3 57561
Affinity Capture-MS Homo sapiens
64 LACTB2 51110
Co-fractionation Homo sapiens
65 MSRB3 253827
Co-fractionation Homo sapiens
66 ACAD9 28976
Proximity Label-MS Homo sapiens
67 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
68 HAX1  
Proximity Label-MS Homo sapiens
69 HSPD1 3329
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 KRT19 3880
Proximity Label-MS Homo sapiens
71 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
72 MCUR1 63933
Proximity Label-MS Homo sapiens
73 NIT2 56954
Co-fractionation Homo sapiens
74 NIPSNAP3A  
Affinity Capture-MS Homo sapiens
75 CLPP 8192
Proximity Label-MS Homo sapiens
76 CS 1431
Proximity Label-MS Homo sapiens
77 PHB2 11331
Proximity Label-MS Homo sapiens
78 TSFM 10102
Proximity Label-MS Homo sapiens
79 AUH 549
Proximity Label-MS Homo sapiens
80 VAC14 55697
Affinity Capture-MS Homo sapiens
81 DNAJA2 10294
Proximity Label-MS Homo sapiens
82 PDHA1 5160
Proximity Label-MS Homo sapiens
83 GABARAPL2 11345
Co-fractionation Homo sapiens
84 SEPT10 151011
Proximity Label-MS Homo sapiens
85 HRSP12 10247
Co-fractionation Homo sapiens
86 NDUFS7 374291
Affinity Capture-MS Homo sapiens
87 FKBP1A 2280
Co-fractionation Homo sapiens
88 C21orf33  
Proximity Label-MS Homo sapiens
89 SSBP1 6742
Proximity Label-MS Homo sapiens
90 ANAPC2 29882
Proximity Label-MS Homo sapiens
91 TXN 7295
Co-fractionation Homo sapiens
92 AARS2  
Proximity Label-MS Homo sapiens
93 ACOT1 641371
Co-fractionation Homo sapiens
94 LRRC61 65999
Proximity Label-MS Homo sapiens
95 C1QBP 708
Proximity Label-MS Homo sapiens
96 PEX5 5830
Protein-peptide Homo sapiens
97 YBEY  
Affinity Capture-MS Homo sapiens
98 AK1 203
Co-fractionation Homo sapiens
View the network image/svg+xml



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