Gene description for GIMAP8
Gene name GTPase, IMAP family member 8
Gene symbol GIMAP8
Other names/aliases IAN-9
IAN6
IAN9
IANT
Species Homo sapiens
 Database cross references - GIMAP8
ExoCarta ExoCarta_155038
Vesiclepedia VP_155038
Entrez Gene 155038
HGNC 21792
UniProt Q8ND71  
 GIMAP8 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for GIMAP8
Molecular Function
    GTP binding GO:0005525 IEA
Biological Process
    regulation of T cell apoptotic process GO:0070232 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    endoplasmic reticulum GO:0005783 IBA
    Golgi apparatus GO:0005794 IEA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified GIMAP8 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GIMAP8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POLR3E 55718
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 COA4  
Co-fractionation Homo sapiens
3 GABARAPL2 11345
Co-fractionation Homo sapiens
4 TXN2 25828
Co-fractionation Homo sapiens
5 AK2 204
Co-fractionation Homo sapiens
6 MTPN 136319
Co-fractionation Homo sapiens
7 SRP72 6731
Affinity Capture-MS Homo sapiens
8 TCOF1 6949
Co-fractionation Homo sapiens
9 PRDX5 25824
Co-fractionation Homo sapiens
10 FAHD1 81889
Co-fractionation Homo sapiens
11 TXNDC12 51060
Co-fractionation Homo sapiens
12 NUDT19 390916
Co-fractionation Homo sapiens
13 OAS2 4939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 APP 351
Reconstituted Complex Homo sapiens
15 SRP54 6729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 TXN 7295
Co-fractionation Homo sapiens
17 FUS 2521
Affinity Capture-MS Homo sapiens
18 PTRHD1 391356
Co-fractionation Homo sapiens
19 AK3 50808
Co-fractionation Homo sapiens
20 LRRC45  
Affinity Capture-MS Homo sapiens
21 CTNNA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 FXN  
Co-fractionation Homo sapiens
23 AK1 203
Co-fractionation Homo sapiens
24 PAK6 56924
Affinity Capture-MS Homo sapiens
25 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GIMAP8 is involved
No pathways found





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