Gene description for POLR3E
Gene name polymerase (RNA) III (DNA directed) polypeptide E (80kD)
Gene symbol POLR3E
Other names/aliases RPC5
SIN
Species Homo sapiens
 Database cross references - POLR3E
ExoCarta ExoCarta_55718
Vesiclepedia VP_55718
Entrez Gene 55718
HGNC 30347
UniProt Q9NVU0  
 POLR3E identified in sEVs derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for POLR3E
Biological Process
    innate immune response GO:0045087 IEA
    defense response to virus GO:0051607 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    RNA polymerase III complex GO:0005666 IBA
    RNA polymerase III complex GO:0005666 IDA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified POLR3E in sEVs
1
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for POLR3E
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POLR2B 5431
Affinity Capture-MS Homo sapiens
2 POLR2G 5436
Affinity Capture-MS Homo sapiens
3 PDHA1 5160
Affinity Capture-MS Homo sapiens
4 FMNL1 752
Affinity Capture-MS Homo sapiens
5 TRMT1L 81627
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 Ruvbl1 56505
Affinity Capture-MS Mus musculus
7 RPS19BP1  
Affinity Capture-MS Homo sapiens
8 RPA2 6118
Proximity Label-MS Homo sapiens
9 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
10 TMEM263 90488
Affinity Capture-MS Homo sapiens
11 URI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 PPP1CC 5501
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 SLC25A14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 PRDX3 10935
Affinity Capture-MS Homo sapiens
15 POLR2I 5438
Affinity Capture-MS Homo sapiens
16 POLR3G  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 POLR1E  
Affinity Capture-MS Homo sapiens
18 CRCP  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SLC25A19  
Affinity Capture-MS Homo sapiens
20 PSMG1 8624
Affinity Capture-MS Homo sapiens
21 POLR2C 5432
Affinity Capture-MS Homo sapiens
22 GPN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 POLR2M  
Affinity Capture-MS Homo sapiens
24 PFDN6 10471
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 MED4 29079
Affinity Capture-MS Homo sapiens
26 GPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 POLR2K  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 POLR1A 25885
Affinity Capture-MS Homo sapiens
29 BAG5 9529
Affinity Capture-MS Homo sapiens
30 PPP1CA 5499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 RBP4 5950
Affinity Capture-MS Homo sapiens
32 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
33 UXT 8409
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 POLR3K  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 PARK2  
Affinity Capture-MS Homo sapiens
36 PSME1 5720
Affinity Capture-MS Homo sapiens
37 POLR3F  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 BDP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PFDN2 5202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 SLC25A20 788
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 ACADM 34
Affinity Capture-MS Homo sapiens
42 TPRKB 51002
Affinity Capture-MS Homo sapiens
43 POLR3GL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 CD3EAP  
Affinity Capture-MS Homo sapiens
45 BRF1  
Affinity Capture-MS Homo sapiens
46 GTF3C3 9330
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 GIMAP8 155038
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 POLR3A 11128
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 POLR2H 5437
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 MAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 POLR2E 5434
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ACAD11 84129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 RPRD2  
Affinity Capture-MS Homo sapiens
54 CKAP2  
Affinity Capture-MS Homo sapiens
55 RPRD1A  
Affinity Capture-MS Homo sapiens
56 POLR2D  
Affinity Capture-MS Homo sapiens
57 POLR3B 55703
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 POLR2A 5430
Affinity Capture-MS Homo sapiens
59 UVRAG  
Affinity Capture-MS Homo sapiens
60 TUBA4A 7277
Affinity Capture-MS Homo sapiens
61 GNB2 2783
Affinity Capture-MS Homo sapiens
62 EGFR 1956
Negative Genetic Homo sapiens
63 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
64 TSFM 10102
Affinity Capture-MS Homo sapiens
65 RPAP3 79657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 Kctd5  
Affinity Capture-MS Mus musculus
67 RAE1 8480
Affinity Capture-MS Homo sapiens
68 HK2 3099
Affinity Capture-MS Homo sapiens
69 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
70 POLR2F  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 SLC25A6 293
Affinity Capture-MS Homo sapiens
72 POLR2J  
Affinity Capture-MS Homo sapiens
73 POLR1B 84172
Affinity Capture-MS Homo sapiens
74 RUVBL2 10856
Affinity Capture-MS Homo sapiens
75 POLR2L 5441
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 TRIM52  
Affinity Capture-MS Homo sapiens
77 POLR3C 10623
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 POLR1C 9533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 WDR92 116143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 POLR3H  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 KEAP1 9817
Affinity Capture-MS Homo sapiens
82 SNRPA 6626
Affinity Capture-MS Homo sapiens
83 RPAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 SUPT6H 6830
Affinity Capture-MS Homo sapiens
85 POLR3D  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CYP2E1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 BCCIP 56647
Co-fractionation Homo sapiens
88 RPRD1B 58490
Affinity Capture-MS Homo sapiens
89 PIH1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 ZNRD1  
Affinity Capture-MS Homo sapiens
91 KRAS 3845
Negative Genetic Homo sapiens
92 POLR1D 51082
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 SSRP1 6749
Affinity Capture-Western Homo sapiens
94 PDRG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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