Gene description for POLR3E
Gene name polymerase (RNA) III (DNA directed) polypeptide E (80kD)
Gene symbol POLR3E
Other names/aliases RPC5
SIN
Species Homo sapiens
 Database cross references - POLR3E
ExoCarta ExoCarta_55718
Vesiclepedia VP_55718
Entrez Gene 55718
HGNC 30347
UniProt Q9NVU0  
 POLR3E identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for POLR3E
Molecular Function
    RNA polymerase III activity GO:0001056 IBA
Biological Process
    gene expression GO:0010467 TAS
    positive regulation of type I interferon production GO:0032481 TAS
    innate immune response GO:0045087 TAS
    termination of RNA polymerase III transcription GO:0006386 TAS
    transcription from RNA polymerase III promoter GO:0006383 TAS
    transcription elongation from RNA polymerase III promoter GO:0006385 TAS
    defense response to virus GO:0051607 IEA
Subcellular Localization
    centrosome GO:0005813 IDA
    nucleus GO:0005634 IDA
    DNA-directed RNA polymerase III complex GO:0005666 IDA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 TAS
 Experiment description of studies that identified POLR3E in exosomes
1
Experiment ID 196
MISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
MISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
EV Enriched markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for POLR3E
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 POLR3D  
Invivo Homo sapiens
2 POLR3A 11128
Invivo Homo sapiens
Invitro Homo sapiens
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