Gene description for TMEM263
Gene name transmembrane protein 263
Gene symbol TMEM263
Other names/aliases C12orf23
Species Homo sapiens
 Database cross references - TMEM263
ExoCarta ExoCarta_90488
Vesiclepedia VP_90488
Entrez Gene 90488
HGNC 28281
UniProt Q8WUH6  
 TMEM263 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TMEM263
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified TMEM263 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TMEM263
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CRBN  
Affinity Capture-MS Homo sapiens
2 Mtx1  
Affinity Capture-MS Mus musculus
3 Mtx2  
Affinity Capture-MS Mus musculus
4 STARD8  
Affinity Capture-MS Homo sapiens
5 Anapc2  
Affinity Capture-MS Mus musculus
6 ECT2L  
Affinity Capture-MS Homo sapiens
7 HSPA5 3309
Affinity Capture-MS Homo sapiens
8 NAAA  
Affinity Capture-MS Homo sapiens
9 Cd2ap 12488
Affinity Capture-MS Mus musculus
10 Ruvbl1 56505
Affinity Capture-MS Mus musculus
11 RBM8A 9939
Affinity Capture-MS Homo sapiens
12 FGD2 221472
Affinity Capture-MS Homo sapiens
13 SLC2A4  
Affinity Capture-MS Homo sapiens
14 ITLN1 55600
Affinity Capture-MS Homo sapiens
15 MCF2L2 23101
Affinity Capture-MS Homo sapiens
16 MFSD4  
Affinity Capture-MS Homo sapiens
17 RACGAP1 29127
Affinity Capture-MS Homo sapiens
18 BTF3 689
Affinity Capture-MS Homo sapiens
19 SLC25A22  
Affinity Capture-MS Homo sapiens
20 WDR45B 56270
Affinity Capture-MS Homo sapiens
21 ARF3 377
Proximity Label-MS Homo sapiens
22 LENG8  
Affinity Capture-MS Homo sapiens
23 TUBA4A 7277
Affinity Capture-MS Homo sapiens
24 CHIA  
Affinity Capture-MS Homo sapiens
25 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
26 LNPEP 4012
Affinity Capture-MS Homo sapiens
27 Ddb1 13194
Affinity Capture-MS Mus musculus
28 AQP3  
Affinity Capture-MS Homo sapiens
29 DOCK8 81704
Affinity Capture-MS Homo sapiens
30 MSX2  
Affinity Capture-MS Homo sapiens
31 SLC2A8 29988
Affinity Capture-MS Homo sapiens
32 C1orf112  
Affinity Capture-MS Homo sapiens
33 POLR3E 55718
Affinity Capture-MS Homo sapiens
34 TBCE 6905
Affinity Capture-MS Homo sapiens
35 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
36 DNAJB6 10049
Affinity Capture-MS Homo sapiens
37 ALPI  
Affinity Capture-MS Homo sapiens
38 ARF4 378
Proximity Label-MS Homo sapiens
39 DNAJB8  
Affinity Capture-MS Homo sapiens
40 PLEKHG4  
Affinity Capture-MS Homo sapiens
41 FARP2 9855
Affinity Capture-MS Homo sapiens
42 MASTL  
Affinity Capture-MS Homo sapiens
43 ARHGAP44  
Affinity Capture-MS Homo sapiens
44 MCU 90550
Proximity Label-MS Homo sapiens
45 TUBA1C 84790
Affinity Capture-MS Homo sapiens
46 ARHGAP36  
Affinity Capture-MS Homo sapiens
47 SWAP70 23075
Affinity Capture-MS Homo sapiens
48 Tube1  
Affinity Capture-MS Mus musculus
49 COPE 11316
Affinity Capture-MS Homo sapiens
50 ARF1 375
Proximity Label-MS Homo sapiens
51 RRM2B 50484
Affinity Capture-MS Homo sapiens
52 WDR5B  
Affinity Capture-MS Homo sapiens
53 GCAT  
Affinity Capture-MS Homo sapiens
54 Kctd5  
Affinity Capture-MS Mus musculus
55 HAX1  
Affinity Capture-MS Homo sapiens
56 PTER 9317
Affinity Capture-MS Homo sapiens
57 Copa 12847
Affinity Capture-MS Mus musculus
58 HSPA12A 259217
Affinity Capture-MS Homo sapiens
59 AQP12B  
Affinity Capture-MS Homo sapiens
60 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
61 ARHGAP31 57514
Affinity Capture-MS Homo sapiens
62 LANCL2 55915
Affinity Capture-MS Homo sapiens
63 FFAR1  
Affinity Capture-MS Homo sapiens
64 AKAP1 8165
Proximity Label-MS Homo sapiens
65 CEPT1 10390
Affinity Capture-MS Homo sapiens
66 FAM71F2  
Affinity Capture-MS Homo sapiens
67 CLDN10  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TMEM263 is involved
No pathways found





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