Gene description for Copa
Gene name coatomer protein complex subunit alpha
Gene symbol Copa
Other names/aliases AU040324
Species Mus musculus
 Database cross references - Copa
ExoCarta ExoCarta_12847
Entrez Gene 12847
UniProt Q8CIE6  
 Copa identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Copa
Molecular Function
    hormone activity GO:0005179 IEA
    structural molecule activity GO:0005198 IEA
Biological Process
    protein transport GO:0015031 IEA
    vesicle-mediated transport GO:0016192 IEA
    pancreatic juice secretion GO:0030157 ISO
    intracellular protein transport GO:0006886 IEA
    transport GO:0006810 IEA
Subcellular Localization
    membrane coat GO:0030117 IEA
    extracellular region GO:0005576 IEA
    extracellular exosome GO:0070062 ISO
    cytoplasmic vesicle GO:0031410 IEA
    COPI vesicle coat GO:0030126 ISO
    cytoplasm GO:0005737 ISO
    extracellular space GO:0005615 ISO
    membrane GO:0016020 ISO
    Golgi apparatus GO:0005794 IEA
 Experiment description of studies that identified Copa in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Copa
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Copa is involved
COPI Mediated Transport IEA Reactome

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