Gene description for Copa
Gene name coatomer protein complex subunit alpha
Gene symbol Copa
Other names/aliases AU040324
xenin
Species Mus musculus
 Database cross references - Copa
ExoCarta ExoCarta_12847
Entrez Gene 12847
UniProt Q8CIE6  
 Copa identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Copa
Molecular Function
    hormone activity GO:0005179 IEA
    structural molecule activity GO:0005198 IEA
Biological Process
    protein transport GO:0015031 IEA
    vesicle-mediated transport GO:0016192 IEA
    pancreatic juice secretion GO:0030157 ISO
    intracellular protein transport GO:0006886 IEA
    transport GO:0006810 IEA
Subcellular Localization
    membrane coat GO:0030117 IEA
    extracellular region GO:0005576 IEA
    extracellular exosome GO:0070062 ISO
    cytoplasmic vesicle GO:0031410 IEA
    COPI vesicle coat GO:0030126 ISO
    cytoplasm GO:0005737 ISO
    extracellular space GO:0005615 ISO
    membrane GO:0016020 ISO
    Golgi apparatus GO:0005794 IEA
 Experiment description of studies that identified Copa in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Copa
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Copa is involved
PathwayEvidenceSource
COPI Mediated Transport IEA Reactome





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