Gene description for FGD2
Gene name	FYVE, RhoGEF and PH domain containing 2
Gene symbol	FGD2
Other names/aliases	ZFYVE4
Species	Homo sapiens
Database cross references - FGD2
ExoCarta	ExoCarta_221472
Entrez Gene	221472
HGNC	3664
MIM	605091
UniProt	Q7Z6J4
FGD2 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for FGD2

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 ISS     Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA     small GTPase binding GO:0031267 ISS     protein binding GO:0005515 IPI     metal ion binding GO:0046872 IEA Biological Process     regulation of cell shape GO:0008360 ISS     regulation of GTPase activity GO:0043087 ISS     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of GTPase activity GO:0043547 ISS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of apoptotic process GO:0043065 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     actin cytoskeleton organization GO:0030036 ISS     cytoskeleton organization GO:0007010 ISS     apoptotic signaling pathway GO:0097190 TAS     filopodium assembly GO:0046847 ISS Subcellular Localization     early endosome membrane GO:0031901 IEA     cytoplasm GO:0005737 ISS     cytoskeleton GO:0005856 IEA     ruffle GO:0001726 ISS     cytosol GO:0005829 TAS     ruffle membrane GO:0032587 IEA     nucleus GO:0005634 IEA     Golgi apparatus GO:0005794 ISS     lamellipodium GO:0030027 ISS