Experiment description of studies that identified POLR1D in sEVs

1 Experiment ID 207 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 208 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 209 MISEV standards ✘ Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ." Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for POLR1D

Protein Interactor ExoCarta ID Identification method PubMed Species 1 POLR2B 5431 Affinity Capture-MS Homo sapiens 2 POLR2G 5436 Affinity Capture-MS Homo sapiens 3 RPSAP58 388524 Affinity Capture-MS Homo sapiens 4 TRMT1L 81627 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 ATL1 51062 Affinity Capture-MS Homo sapiens 6 RRN3   Affinity Capture-MS Homo sapiens 7 NOP9 161424 Co-fractionation Homo sapiens 8 SEPT10 151011 Affinity Capture-MS Homo sapiens 9 KPNB1 3837 Affinity Capture-MS Homo sapiens 10 VPS13A 23230 Affinity Capture-MS Homo sapiens 11 HSP90AB1 3326 Affinity Capture-MS Homo sapiens 12 KARS 3735 Affinity Capture-MS Homo sapiens 13 KPNA2 3838 Affinity Capture-MS Homo sapiens 14 CDK8 1024 Affinity Capture-MS Homo sapiens 15 DNAJB6 10049 Two-hybrid Homo sapiens 16 BRF1   Affinity Capture-MS Homo sapiens 17 MED13 9969 Affinity Capture-MS Homo sapiens 18 RUVBL1 8607 Affinity Capture-MS Homo sapiens 19 POLR2I 5438 Affinity Capture-MS Homo sapiens 20 ANP32B 10541 Affinity Capture-MS Homo sapiens 21 POLR3G   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 MRPL12 6182 Two-hybrid Homo sapiens 23 TWISTNB   Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 POLR1E   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 RSRC1   Affinity Capture-MS Homo sapiens 26 CRCP   Co-fractionation Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 GRWD1 83743 Co-fractionation Homo sapiens 28 DDX18 8886 Co-fractionation Homo sapiens 29 POLR2C 5432 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 30 MECP2 4204 Affinity Capture-MS Homo sapiens 31 POLR2M   Affinity Capture-MS Homo sapiens 32 MYCN   Affinity Capture-MS Homo sapiens 33 ASNSD1   Affinity Capture-MS Homo sapiens 34 PFDN6 10471 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 MED4 29079 Affinity Capture-MS Homo sapiens 36 GPN3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 POLR2K   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 GOLGA2 2801 Affinity Capture-MS Homo sapiens 39 POLR1A 25885 Co-fractionation Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 E2F4   Two-hybrid Homo sapiens 41 UBN2   Affinity Capture-MS Homo sapiens 42 UXT 8409 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 POLR3K   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 PPP1R9A   Affinity Capture-MS Homo sapiens 45 TUBA1A 7846 Affinity Capture-MS Homo sapiens 46 SPSB3   Affinity Capture-MS Homo sapiens 47 POLR3F   Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 BDP1   Affinity Capture-MS Homo sapiens 49 GCC2 9648 Affinity Capture-MS Homo sapiens 50 PFDN2 5202 Affinity Capture-MS Homo sapiens 51 DEK 7913 Affinity Capture-MS Homo sapiens 52 POLR3D   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 CRKL 1399 Two-hybrid Homo sapiens 54 MAPRE2 10982 Affinity Capture-MS Homo sapiens 55 NOB1   Co-fractionation Homo sapiens 56 CTR9 9646 Affinity Capture-MS Homo sapiens 57 MBD3 53615 Affinity Capture-MS Homo sapiens 58 PICALM 8301 Affinity Capture-MS Homo sapiens 59 POLR3GL   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 MPDZ   Affinity Capture-MS Homo sapiens 61 SYBU   Affinity Capture-MS Homo sapiens 62 CACYBP 27101 Affinity Capture-MS Homo sapiens 63 CD3EAP   Far Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 TCP10   Affinity Capture-MS Homo sapiens 65 RNF213 57674 Affinity Capture-MS Homo sapiens 66 GTF3C3 9330 Affinity Capture-MS Homo sapiens 67 IPO5 3843 Affinity Capture-MS Homo sapiens 68 POLR3A 11128 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 POLR2H 5437 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 TBKBP1   Affinity Capture-MS Homo sapiens 71 MAF1   Affinity Capture-MS Homo sapiens 72 MAGEA11   Two-hybrid Homo sapiens 73 DHX15 1665 Affinity Capture-MS Homo sapiens 74 AKAP9 10142 Affinity Capture-MS Homo sapiens 75 POLR2E 5434 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 RPRD2   Affinity Capture-MS Homo sapiens 77 NR3C1 2908 Two-hybrid Homo sapiens 78 DCAF13 25879 Co-fractionation Homo sapiens 79 GPN1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 RPRD1A   Affinity Capture-MS Homo sapiens 81 OSGEP 55644 Affinity Capture-MS Homo sapiens 82 TFPT   Affinity Capture-MS Homo sapiens 83 ANP32E 81611 Affinity Capture-MS Homo sapiens 84 POLR2A 5430 Affinity Capture-MS Homo sapiens 85 POLR3E 55718 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 CDC42 998 Affinity Capture-MS Homo sapiens 87 POLR2D   Affinity Capture-MS Homo sapiens 88 MYC   Affinity Capture-MS Homo sapiens 89 TMEM184C   Affinity Capture-MS Homo sapiens 90 RPAP3 79657 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 91 BAZ1A 11177 Affinity Capture-MS Homo sapiens 92 PGAM1 5223 Affinity Capture-MS Homo sapiens 93 HAX1   Two-hybrid Homo sapiens 94 CEBPA   Protein-peptide Homo sapiens 95 HEATR1 55127 Affinity Capture-MS Homo sapiens 96 TSR1 55720 Co-fractionation Homo sapiens 97 CDC42EP4   Affinity Capture-MS Homo sapiens 98 CDC25A   Two-hybrid Homo sapiens 99 POLR2F   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 GRB2 2885 Two-hybrid Homo sapiens 101 POLR2J   Affinity Capture-MS Homo sapiens 102 TP53 7157 Synthetic Growth Defect Homo sapiens 103 POLR1B 84172 Co-fractionation Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 104 INPPL1 3636 Affinity Capture-MS Homo sapiens 105 POLR2L 5441 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 106 POLR3C 10623 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 107 POLR1C 9533 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 108 WDR92 116143 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 109 POLR3H   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 110 MEN1 4221 Affinity Capture-MS Homo sapiens 111 RPAP1   Affinity Capture-MS Homo sapiens 112 RPAP2   Affinity Capture-MS Homo sapiens 113 RUVBL2 10856 Affinity Capture-MS Homo sapiens 114 TRIP12 9320 Affinity Capture-MS Homo sapiens 115 SKAP1 8631 Affinity Capture-MS Homo sapiens 116 DDIT3 1649 Two-hybrid Homo sapiens 117 URI1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 118 DNAJB4 11080 Two-hybrid Homo sapiens 119 PXN 5829 Two-hybrid Homo sapiens 120 TMEM38B   Affinity Capture-MS Homo sapiens 121 POLR3B 55703 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 122 RPRD1B 58490 Affinity Capture-MS Homo sapiens 123 PIH1D1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 124 ZNRD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 125 PDRG1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 RANBP2 5903 Affinity Capture-MS Homo sapiens View the network

Pathways in which POLR1D is involved

No pathways found