Gene description for TUBA1A
Gene name tubulin, alpha 1a
Gene symbol TUBA1A
Other names/aliases B-ALPHA-1
LIS3
TUBA3
Species Homo sapiens
 Database cross references - TUBA1A
ExoCarta ExoCarta_7846
Vesiclepedia VP_7846
Entrez Gene 7846
HGNC 20766
MIM 602529
UniProt Q71U36  
 TUBA1A identified in sEVs derived from the following tissue/cell type
B cells 12519789    
Breast cancer cells 19415654    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Saliva 19199708    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for TUBA1A
Molecular Function
    structural molecule activity GO:0005198 TAS
    structural constituent of cytoskeleton GO:0005200 IBA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    hydrolase activity GO:0016787 IEA
    identical protein binding GO:0042802 IPI
    protein-containing complex binding GO:0044877 IEA
    metal ion binding GO:0046872 IEA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    mitotic cell cycle GO:0000278 IBA
    neuron migration GO:0001764 IEA
    startle response GO:0001964 IEA
    intracellular protein transport GO:0006886 IEA
    microtubule-based process GO:0007017 TAS
    centrosome cycle GO:0007098 IEA
    smoothened signaling pathway GO:0007224 IEA
    memory GO:0007613 IEA
    adult locomotory behavior GO:0008344 IEA
    visual learning GO:0008542 IEA
    response to mechanical stimulus GO:0009612 IEA
    glial cell differentiation GO:0010001 IEA
    gene expression GO:0010467 IEA
    dentate gyrus development GO:0021542 IEA
    cerebellar cortex morphogenesis GO:0021696 IEA
    pyramidal neuron differentiation GO:0021859 IEA
    cerebral cortex development GO:0021987 IEA
    flagellated sperm motility GO:0030317 IEA
    cytoskeleton-dependent intracellular transport GO:0030705 TAS
    response to tumor necrosis factor GO:0034612 IEA
    locomotory exploration behavior GO:0035641 IEA
    microtubule polymerization GO:0046785 IEA
    forebrain morphogenesis GO:0048853 IEA
    homeostasis of number of cells within a tissue GO:0048873 IEA
    regulation of synapse organization GO:0050807 IEA
    synapse organization GO:0050808 IEA
    cell division GO:0051301 TAS
    neuron apoptotic process GO:0051402 IEA
    motor behavior GO:0061744 IEA
    cellular response to calcium ion GO:0071277 IEA
    organelle transport along microtubule GO:0072384 IEA
    neuron projection arborization GO:0140058 IEA
    response to L-glutamate GO:1902065 IEA
Subcellular Localization
    condensed chromosome GO:0000793 IEA
    nucleus GO:0005634 HDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    microtubule GO:0005874 IBA
    microtubule GO:0005874 IDA
    microtubule GO:0005874 TAS
    axonemal microtubule GO:0005879 IDA
    plasma membrane GO:0005886 IEA
    microtubule cytoskeleton GO:0015630 IDA
    neuromuscular junction GO:0031594 IEA
    sperm flagellum GO:0036126 IEA
    cytoplasmic ribonucleoprotein granule GO:0036464 IDA
    recycling endosome GO:0055037 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified TUBA1A in sEVs
1
Experiment ID 11
MISEV standards
✘ Biophysical techniques
✔
HSC70|HSP90|MHCII|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 12519789    
Organism Homo sapiens
Experiment description Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
Authors "Wubbolts R, Leckie RS, Veenhuizen PT, Schwarzmann G, Mobius W, Hoernschemeyer J, Slot JW, Geuze HJ, Stoorvogel W"
Journal name JBC
Publication year 2003
Sample B cells
Sample name RN (HLA-DR15+)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [MALDI TOF]
Mass spectrometry [QTOF]
Western blotting
Thin layer chromatography
HPLC
2
Experiment ID 65
MISEV standards
✘ Biophysical techniques
✔
HSP60|HSP27|GAPDH|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors "Staubach S, Razawi H, Hanisch FG."
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
3
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
4
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
27
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
28
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
37
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
40
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
54
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
55
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
56
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
59
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
60
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
61
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
62
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TUBA1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 PPP2R4 5524
Affinity Capture-Western Homo sapiens
3 UBL4A 8266
Affinity Capture-MS Homo sapiens
4 TIMM17A  
Two-hybrid Homo sapiens
5 TK1 7083
Two-hybrid Homo sapiens
6 NLRP1  
Affinity Capture-MS Homo sapiens
7 LLGL1 3996
Synthetic Lethality Homo sapiens
8 DAG1 1605
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
FRET Homo sapiens
9 SKI 6497
Affinity Capture-MS Homo sapiens
10 CRK 1398
Affinity Capture-MS Homo sapiens
11 NFATC1 4772
Reconstituted Complex Homo sapiens
12 DNAJB2 3300
Affinity Capture-MS Homo sapiens
13 NMRAL1 57407
Affinity Capture-MS Homo sapiens
14 UBC 7316
Affinity Capture-Western Homo sapiens
15 VHL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
16 KEL  
Two-hybrid Homo sapiens
17 TMEM72  
Affinity Capture-MS Homo sapiens
18 LRRN4CL 221091
Affinity Capture-MS Homo sapiens
19 CDKN1A  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
20 EFNA3  
Affinity Capture-MS Homo sapiens
21 HDAC3 8841
Co-fractionation Homo sapiens
22 WDR76  
Affinity Capture-MS Homo sapiens
23 TRMU  
Affinity Capture-MS Homo sapiens
24 APBB2  
Affinity Capture-MS Homo sapiens
25 FAM174A 345757
Affinity Capture-MS Homo sapiens
26 NUDT3 11165
Two-hybrid Homo sapiens
27 CLEC2B  
Affinity Capture-MS Homo sapiens
28 GLMP 112770
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 THTPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 POU5F1  
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
31 ATAD5  
Synthetic Lethality Homo sapiens
32 ARMCX3 51566
Co-fractionation Homo sapiens
33 MAGED2 10916
Affinity Capture-MS Homo sapiens
34 SHC1 6464
Affinity Capture-MS Homo sapiens
35 ABHD17A 81926
Affinity Capture-MS Homo sapiens
36 LAMTOR4 389541
Affinity Capture-MS Homo sapiens
37 PRTN3 5657
Affinity Capture-MS Homo sapiens
38 Kif2c 73804
Affinity Capture-MS Mus musculus
39 DHDH  
Affinity Capture-MS Homo sapiens
40 UPK3B  
Affinity Capture-MS Homo sapiens
41 TMEM25  
Affinity Capture-MS Homo sapiens
42 ANXA7 310
Two-hybrid Homo sapiens
43 SULT1C4  
Affinity Capture-MS Homo sapiens
44 VAV1 7409
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
45 SDF2 6388
Affinity Capture-MS Homo sapiens
46 ASCL2  
Affinity Capture-Western Homo sapiens
47 ITGAD  
Affinity Capture-MS Homo sapiens
48 P2RY8  
Affinity Capture-MS Homo sapiens
49 GALNT12 79695
Affinity Capture-MS Homo sapiens
50 TRMT61A 115708
Affinity Capture-MS Homo sapiens
51 COMTD1 118881
Affinity Capture-MS Homo sapiens
52 UBAC2 337867
Affinity Capture-MS Homo sapiens
53 YAP1 10413
Affinity Capture-MS Homo sapiens
54 TTN 7273
Synthetic Lethality Homo sapiens
55 OGT 8473
Reconstituted Complex Homo sapiens
56 ALKBH3  
Affinity Capture-MS Homo sapiens
57 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
58 PEX14 5195
Co-purification Homo sapiens
59 YWHAQ 10971
Reconstituted Complex Homo sapiens
60 ANAPC4 29945
Affinity Capture-MS Homo sapiens
61 DDX39B 7919
Affinity Capture-MS Homo sapiens
62 VDAC2 7417
Co-fractionation Homo sapiens
63 HSPB8 26353
Affinity Capture-MS Homo sapiens
64 FAM43A  
Affinity Capture-MS Homo sapiens
65 KLHL14 57565
Affinity Capture-MS Homo sapiens
66 DCDC5  
Affinity Capture-Western Homo sapiens
67 PHLPP1  
Proximity Label-MS Homo sapiens
68 ADAMTS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 TTC26 79989
Affinity Capture-MS Homo sapiens
70 ELMO3 79767
Affinity Capture-MS Homo sapiens
71 HTRA2 27429
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
72 NUBP2 10101
Affinity Capture-MS Homo sapiens
73 CD79B 974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 LRRC25  
Affinity Capture-MS Homo sapiens
75 IQCB1  
Affinity Capture-MS Homo sapiens
76 CUL3 8452
Affinity Capture-MS Homo sapiens
77 YWHAZ 7534
Synthetic Lethality Homo sapiens
78 FAM187B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 ALDH3B1 221
Affinity Capture-MS Homo sapiens
80 TXNDC9 10190
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 SPCS3 60559
Affinity Capture-MS Homo sapiens
82 C16orf93  
Affinity Capture-MS Homo sapiens
83 TUBA4A 7277
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 PRMT5 10419
Co-fractionation Homo sapiens
85 Uso1 56041
Affinity Capture-MS Mus musculus
86 SOHLH1  
Affinity Capture-MS Homo sapiens
87 NAAA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 GML  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 ING5  
Synthetic Lethality Homo sapiens
90 NSUN5P1  
Affinity Capture-MS Homo sapiens
91 OBSCN 84033
Affinity Capture-MS Homo sapiens
92 AP1M2 10053
Affinity Capture-MS Homo sapiens
93 TCP11L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 ACTL6B  
Affinity Capture-MS Homo sapiens
95 PELI3  
Affinity Capture-MS Homo sapiens
96 BTG1 694
Two-hybrid Homo sapiens
97 Lrr1  
Affinity Capture-MS Mus musculus
98 NFATC2  
Affinity Capture-Western Homo sapiens
99 STK16 8576
Affinity Capture-MS Homo sapiens
100 PAFAH1B1 5048
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
101 C8orf33 65265
Two-hybrid Homo sapiens
102 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
103 TBC1D3  
Affinity Capture-Western Homo sapiens
104 LIPH 200879
Affinity Capture-MS Homo sapiens
105 MDK 4192
Affinity Capture-MS Homo sapiens
106 TFPT  
Affinity Capture-MS Homo sapiens
107 DFFA 1676
Co-fractionation Homo sapiens
108 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
109 PFDN1 5201
Reconstituted Complex Homo sapiens
110 CHRM4  
Affinity Capture-MS Homo sapiens
111 MORF4L2  
Affinity Capture-MS Homo sapiens
112 PDDC1 347862
Affinity Capture-MS Homo sapiens
113 HSP90AA1 3320
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
114 CLEC4C  
Affinity Capture-MS Homo sapiens
115 Tuba3a 22144
Affinity Capture-MS Mus musculus
116 RFPL2  
Affinity Capture-MS Homo sapiens
117 HOXB1  
Affinity Capture-MS Homo sapiens
118 CAPS 828
Affinity Capture-MS Homo sapiens
119 GAPDH 2597
Co-fractionation Homo sapiens
120 Cdc37 12539
Affinity Capture-MS Mus musculus
121 AIMP2 7965
Affinity Capture-MS Homo sapiens
122 CST11  
Affinity Capture-MS Homo sapiens
123 TXNIP 10628
Affinity Capture-MS Homo sapiens
124 POLR1D 51082
Affinity Capture-MS Homo sapiens
125 ASB14  
Affinity Capture-MS Homo sapiens
126 LY86  
Affinity Capture-MS Homo sapiens
127 PRKAA1 5562
Affinity Capture-MS Homo sapiens
128 LILRA5  
Affinity Capture-MS Homo sapiens
129 CD48 962
Affinity Capture-MS Homo sapiens
130 KLK5 25818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 HLA-B 3106
Affinity Capture-MS Homo sapiens
132 TTR 7276
Two-hybrid Homo sapiens
133 UCHL1 7345
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
134 NOP56 10528
Affinity Capture-MS Homo sapiens
135 DTNA  
Affinity Capture-MS Homo sapiens
136 HSP90AB1 3326
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
137 B3GALT4  
Affinity Capture-MS Homo sapiens
138 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
139 LRP1 4035
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 PACRG 135138
Affinity Capture-MS Homo sapiens
141 TLN1 7094
FRET Homo sapiens
142 HEY1  
Affinity Capture-MS Homo sapiens
143 F9 2158
Affinity Capture-MS Homo sapiens
144 SYK 6850
Biochemical Activity Homo sapiens
145 PRDX2 7001
Affinity Capture-MS Homo sapiens
146 NR4A1  
Affinity Capture-MS Homo sapiens
147 ABHD14A  
Affinity Capture-MS Homo sapiens
148 TUBA3C 7278
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 TOMM40 10452
Co-fractionation Homo sapiens
150 FAM196A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 FOXD4  
Affinity Capture-MS Homo sapiens
152 TIMM50 92609
Affinity Capture-MS Homo sapiens
153 NPAS1  
Affinity Capture-MS Homo sapiens
154 WFDC11  
Affinity Capture-MS Homo sapiens
155 C9orf163  
Affinity Capture-MS Homo sapiens
156 IQCF2  
Affinity Capture-MS Homo sapiens
157 GSK3B 2932
Two-hybrid Homo sapiens
158 ITLN1 55600
Affinity Capture-MS Homo sapiens
159 ACOT11 26027
Affinity Capture-MS Homo sapiens
160 SLC25A10 1468
Affinity Capture-MS Homo sapiens
161 MIB1 57534
Proximity Label-MS Homo sapiens
162 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
163 RUFY1 80230
Affinity Capture-MS Homo sapiens
164 PPP4R1L  
Affinity Capture-MS Homo sapiens
165 PSMD14 10213
Affinity Capture-MS Homo sapiens
166 CBL 867
Affinity Capture-Western Homo sapiens
167 CAPSL  
Affinity Capture-MS Homo sapiens
168 LRRC29  
Affinity Capture-MS Homo sapiens
169 S100A8 6279
Reconstituted Complex Homo sapiens
170 PLK1 5347
Affinity Capture-Western Homo sapiens
171 THBS3 7059
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 PKN1 5585
Affinity Capture-Western Homo sapiens
173 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 Bag2  
Affinity Capture-MS Mus musculus
175 HUS1B  
Affinity Capture-MS Homo sapiens
176 GEMIN7  
Two-hybrid Homo sapiens
177 RPLP0P6 220717
Co-fractionation Homo sapiens
178 GET4 51608
Affinity Capture-MS Homo sapiens
179 Ksr1  
Affinity Capture-MS Mus musculus
180 CYLD  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
181 BRINP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 UPK2 7379
Affinity Capture-MS Homo sapiens
183 CDC14A  
Synthetic Lethality Homo sapiens
184 TUBB 203068
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
185 AIFM1 9131
Affinity Capture-MS Homo sapiens
186 ICAM2 3384
Affinity Capture-MS Homo sapiens
187 ICAM1 3383
Affinity Capture-MS Homo sapiens
188 RC3H2  
Affinity Capture-MS Homo sapiens
189 TNFSF8  
Affinity Capture-MS Homo sapiens
190 KLK11 11012
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 PTH2R  
Affinity Capture-MS Homo sapiens
192 PRG2  
Affinity Capture-MS Homo sapiens
193 MX1 4599
Two-hybrid Homo sapiens
194 RICTOR 253260
Affinity Capture-MS Homo sapiens
195 TUBB4B 10383
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
196 EGFR 1956
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
197 KLRD1  
Affinity Capture-MS Homo sapiens
198 NUP43 348995
Proximity Label-MS Homo sapiens
199 PTK2 5747
Proximity Label-MS Homo sapiens
200 FUS 2521
Affinity Capture-MS Homo sapiens
201 AQP3  
Affinity Capture-MS Homo sapiens
202 MORF4L1  
Affinity Capture-MS Homo sapiens
203 SERPINB11  
Affinity Capture-MS Homo sapiens
204 WEE1 7465
Synthetic Lethality Homo sapiens
205 RPS27 6232
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 CEP250 11190
Affinity Capture-MS Homo sapiens
207 TAOK2 9344
Reconstituted Complex Homo sapiens
208 BAG1 573
Affinity Capture-MS Homo sapiens
209 IL12RB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 ALDH3B2  
Affinity Capture-MS Homo sapiens
211 CDK20  
Affinity Capture-MS Homo sapiens
212 TRAC  
Affinity Capture-MS Homo sapiens
213 DDRGK1 65992
Affinity Capture-MS Homo sapiens
214 NXPH3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 EDN3  
Affinity Capture-MS Homo sapiens
216 CBWD1 55871
Affinity Capture-MS Homo sapiens
217 INSL5  
Affinity Capture-MS Homo sapiens
218 PRSS22 64063
Affinity Capture-MS Homo sapiens
219 LYZL2  
Affinity Capture-MS Homo sapiens
220 MAP2K2 5605
Affinity Capture-MS Homo sapiens
221 FCGR3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
222 PRKCSH 5589
Affinity Capture-MS Homo sapiens
223 STARD13 90627
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
224 VDAC3 7419
Co-fractionation Homo sapiens
225 TTC1 7265
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
226 PRKY  
Affinity Capture-MS Homo sapiens
227 TTC5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 HLA-DMB 3109
Affinity Capture-MS Homo sapiens
229 TP53 7157
Affinity Capture-MS Homo sapiens
230 TSPYL6  
Affinity Capture-MS Homo sapiens
231 PDCD6IP 10015
Affinity Capture-Western Homo sapiens
232 SH2D3A  
Affinity Capture-MS Homo sapiens
233 LCMT2 9836
Affinity Capture-MS Homo sapiens
234 CLEC2D  
Affinity Capture-MS Homo sapiens
235 SQSTM1 8878
Affinity Capture-Western Homo sapiens
236 FAM83F 113828
Affinity Capture-MS Homo sapiens
237 MAT2B 27430
Co-fractionation Homo sapiens
238 HDAC6 10013
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
239 AARSD1 80755
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
240 ESR1  
Affinity Capture-Western Homo sapiens
241 DDX39A 10212
Affinity Capture-MS Homo sapiens
242 BSG 682
Affinity Capture-MS Homo sapiens
243 DHFR 1719
Affinity Capture-MS Homo sapiens
244 LAGE3  
Affinity Capture-MS Homo sapiens
245 ERRFI1 54206
Affinity Capture-MS Homo sapiens
246 NUP210P1  
Affinity Capture-MS Homo sapiens
247 FAM96A  
Affinity Capture-MS Homo sapiens
248 PSMD1 5707
Co-fractionation Homo sapiens
249 ATOH1  
Affinity Capture-MS Homo sapiens
250 PLAUR 5329
Affinity Capture-MS Homo sapiens
251 ALDH1L2 160428
Affinity Capture-MS Homo sapiens
252 MECP2 4204
Affinity Capture-MS Homo sapiens
253 BRINP2  
Affinity Capture-MS Homo sapiens
254 ATP6V1B2 526
Co-fractionation Homo sapiens
255 RHOF 54509
Affinity Capture-MS Homo sapiens
256 ENDOV  
Affinity Capture-MS Homo sapiens
257 YWHAE 7531
Affinity Capture-MS Homo sapiens
258 DNAJA4 55466
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
259 IGHM 3507
Affinity Capture-MS Homo sapiens
260 TUSC3 7991
Synthetic Lethality Homo sapiens
261 PRMT6  
Affinity Capture-MS Homo sapiens
262 NCOA6  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
263 SLC25A48  
Affinity Capture-MS Homo sapiens
264 CHEK2  
Synthetic Lethality Homo sapiens
265 SLURP1  
Affinity Capture-MS Homo sapiens
266 CELA3A  
Affinity Capture-MS Homo sapiens
267 ZNF44  
Affinity Capture-MS Homo sapiens
268 CTDSP2 10106
Affinity Capture-MS Homo sapiens
269 TPSB2  
Affinity Capture-MS Homo sapiens
270 PFN3  
Affinity Capture-MS Homo sapiens
271 MCM2 4171
Affinity Capture-MS Homo sapiens
272 D2HGDH 728294
Affinity Capture-MS Homo sapiens
273 HES6  
Affinity Capture-MS Homo sapiens
274 BAGE2  
Affinity Capture-MS Homo sapiens
275 ATG7 10533
Affinity Capture-MS Homo sapiens
276 XRCC3  
Synthetic Lethality Homo sapiens
277 RAB8B 51762
Affinity Capture-Western Homo sapiens
278 B4GALT1 2683
Reconstituted Complex Homo sapiens
279 SYTL4 94121
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
280 TFCP2 7024
Affinity Capture-MS Homo sapiens
281 NCK1 4690
Affinity Capture-MS Homo sapiens
282 USP37  
Proximity Label-MS Homo sapiens
283 HSPA8 3312
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 MAP2 4133
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
285 LAMP3  
Affinity Capture-MS Homo sapiens
286 SCPEP1 59342
Co-fractionation Homo sapiens
287 TSHR 7253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 IRS4 8471
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
289 C2orf27B  
Affinity Capture-MS Homo sapiens
290 TRIM58 25893
Affinity Capture-MS Homo sapiens
291 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 PARK2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
293 B4GALT2  
Affinity Capture-MS Homo sapiens
294 COMMD5 28991
Affinity Capture-MS Homo sapiens
295 BLM 641
Synthetic Lethality Homo sapiens
296 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
297 ALPI  
Affinity Capture-MS Homo sapiens
298 NAGS  
Affinity Capture-MS Homo sapiens
299 SOCS6  
Affinity Capture-MS Homo sapiens
300 RPL5 6125
Co-fractionation Homo sapiens
301 MAPT  
Affinity Capture-Western Homo sapiens
302 RCCD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
303 TUBA1B 10376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
304 BTF3 689
Affinity Capture-MS Homo sapiens
305 NTRK1 4914
Affinity Capture-MS Homo sapiens
306 GPR182  
Affinity Capture-MS Homo sapiens
307 DNAJA1 3301
Affinity Capture-MS Homo sapiens
308 CDHR4  
Affinity Capture-MS Homo sapiens
309 DHFRL1  
Affinity Capture-MS Homo sapiens
310 UBE2D3 7323
Two-hybrid Homo sapiens
311 HDAC5 10014
Affinity Capture-MS Homo sapiens
312 RPL11 6135
Synthetic Lethality Homo sapiens
313 C7orf34  
Affinity Capture-MS Homo sapiens
314 SLX4  
Affinity Capture-MS Homo sapiens
315 SDC3  
Reconstituted Complex Homo sapiens
316 EFNA4  
Affinity Capture-MS Homo sapiens
317 PPM1M  
Affinity Capture-MS Homo sapiens
318 Psma2 19166
Affinity Capture-MS Mus musculus
319 BAG2 9532
Affinity Capture-MS Homo sapiens
320 ECT2 1894
Affinity Capture-MS Homo sapiens
321 B3GNT3 10331
Affinity Capture-MS Homo sapiens
322 RLIM 51132
Affinity Capture-MS Homo sapiens
323 MGARP  
Affinity Capture-MS Homo sapiens
324 PRSS50  
Affinity Capture-MS Homo sapiens
325 PTEN 5728
Synthetic Growth Defect Homo sapiens
326 LOC254896  
Affinity Capture-MS Homo sapiens
327 EIF3F 8665
Affinity Capture-MS Homo sapiens
328 FBXO6 26270
Affinity Capture-MS Homo sapiens
329 METTL21B  
Affinity Capture-MS Homo sapiens
330 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
331 CTAG1B  
Affinity Capture-MS Homo sapiens
332 AP2M1 1173
Affinity Capture-MS Homo sapiens
333 F12  
Affinity Capture-MS Homo sapiens
334 CRYBB3  
Affinity Capture-MS Homo sapiens
335 KLRB1  
Affinity Capture-MS Homo sapiens
336 PRPF19 27339
Affinity Capture-MS Homo sapiens
337 SCGB2A2  
Affinity Capture-MS Homo sapiens
338 MTOR 2475
Synthetic Lethality Homo sapiens
339 INO80  
Affinity Capture-Western Homo sapiens
340 USP50  
Affinity Capture-MS Homo sapiens
341 HLA-DQB1 3119
Affinity Capture-MS Homo sapiens
342 KIAA0368 23392
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
343 HAX1  
Affinity Capture-MS Homo sapiens
344 ISLR 3671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 RBBP5 5929
Co-purification Homo sapiens
346 MAGT1 84061
Affinity Capture-MS Homo sapiens
347 TUBB2A 7280
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
348 SUGT1 10910
Affinity Capture-Western Homo sapiens
349 SUMF2 25870
Affinity Capture-MS Homo sapiens
350 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
351 PHB2 11331
Synthetic Lethality Homo sapiens
352 CDC20 991
Affinity Capture-MS Homo sapiens
353 SMN1 6606
Two-hybrid Homo sapiens
354 CTDSP1 58190
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
355 ZNF695  
Affinity Capture-MS Homo sapiens
356 GP9 2815
Affinity Capture-MS Homo sapiens
357 TXNDC15  
Affinity Capture-MS Homo sapiens
358 OPALIN  
Affinity Capture-MS Homo sapiens
359 LTA  
Affinity Capture-MS Homo sapiens
360 EFNA1  
Affinity Capture-MS Homo sapiens
361 TUBB3 10381
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
362 ERLIN2 11160
Affinity Capture-MS Homo sapiens
363 DNMBP 23268
Affinity Capture-MS Homo sapiens
364 S100A9 6280
Reconstituted Complex Homo sapiens
365 TUBB6 84617
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
366 ZC2HC1B  
Affinity Capture-MS Homo sapiens
367 CEP44  
Co-localization Homo sapiens
368 UFL1 23376
Affinity Capture-MS Homo sapiens
369 CA6 765
Affinity Capture-MS Homo sapiens
370 NAA30 122830
Affinity Capture-MS Homo sapiens
371 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
372 INF2 64423
Affinity Capture-MS Homo sapiens
373 LRRK2 120892
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
374 SPG20 23111
FRET Homo sapiens
375 SERBP1 26135
Affinity Capture-MS Homo sapiens
376 PRKAG3  
Affinity Capture-MS Homo sapiens
377 RC3H1 149041
Affinity Capture-MS Homo sapiens
378 ATXN3 4287
Reconstituted Complex Homo sapiens
379 KIAA1644  
Affinity Capture-MS Homo sapiens
380 CDKN2A 1029
Reconstituted Complex Homo sapiens
381 HLA-C 3107
Affinity Capture-MS Homo sapiens
382 RAMP3  
Affinity Capture-MS Homo sapiens
383 ZMYND19  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
384 KLK15  
Affinity Capture-MS Homo sapiens
385 COIL  
Proximity Label-MS Homo sapiens
386 NME3 4832
Affinity Capture-MS Homo sapiens
387 FAM167A  
Affinity Capture-MS Homo sapiens
388 JMJD4  
Affinity Capture-MS Homo sapiens
389 SSR2  
Affinity Capture-MS Homo sapiens
390 HCST  
Affinity Capture-MS Homo sapiens
391 KPNB1 3837
Reconstituted Complex Homo sapiens
392 WNT7A  
Affinity Capture-MS Homo sapiens
393 FAM110C  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
394 HDHD1  
Affinity Capture-MS Homo sapiens
395 SNX21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 TOMM22 56993
Co-fractionation Homo sapiens
397 EIF4ENIF1 56478
Two-hybrid Homo sapiens
398 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
399 MIOX  
Affinity Capture-MS Homo sapiens
400 KCNQ2  
Affinity Capture-Western Homo sapiens
401 ZAP70 7535
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
402 KIF5B 3799
Affinity Capture-MS Homo sapiens
403 AGO3  
Affinity Capture-MS Homo sapiens
404 RAD51  
Co-fractionation Homo sapiens
405 BCOR  
Affinity Capture-Western Homo sapiens
406 MLST8 64223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
407 CDC73  
Synthetic Lethality Homo sapiens
408 MARK4  
Affinity Capture-MS Homo sapiens
409 MYCN  
Affinity Capture-MS Homo sapiens
410 FAF2 23197
Affinity Capture-MS Homo sapiens
411 COMMD4 54939
Affinity Capture-MS Homo sapiens
412 KCTD13 253980
Affinity Capture-MS Homo sapiens
413 WRN 7486
Synthetic Lethality Homo sapiens
414 C1orf106  
Affinity Capture-MS Homo sapiens
415 RB1 5925
Synthetic Lethality Homo sapiens
416 DNASE2B  
Affinity Capture-MS Homo sapiens
417 EFNA2  
Affinity Capture-MS Homo sapiens
418 TNFSF11  
Affinity Capture-MS Homo sapiens
419 ING4  
Synthetic Lethality Homo sapiens
420 EMD 2010
Proximity Label-MS Homo sapiens
421 CCAR2 57805
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
422 AGK 55750
Affinity Capture-MS Homo sapiens
423 STAU1 6780
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
424 HTT 3064
Affinity Capture-MS Homo sapiens
425 VCL 7414
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
426 PPARD  
Affinity Capture-MS Homo sapiens
427 CHEK1  
Synthetic Lethality Homo sapiens
428 POC1B 282809
Co-localization Homo sapiens
429 TKTL1  
Affinity Capture-MS Homo sapiens
430 DUSP23 54935
Two-hybrid Homo sapiens
431 ATP5B 506
Co-fractionation Homo sapiens
432 DNAJB11 51726
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
433 VSX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 UPP1 7378
Affinity Capture-MS Homo sapiens
435 USP32 84669
Affinity Capture-MS Homo sapiens
436 EML1 2009
Reconstituted Complex Homo sapiens
437 MAT2A 4144
Co-fractionation Homo sapiens
438 ACTN1 87
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
439 GAN 8139
Affinity Capture-MS Homo sapiens
440 C1orf111  
Affinity Capture-MS Homo sapiens
441 VAPB 9217
Affinity Capture-MS Homo sapiens
442 AMBRA1  
Affinity Capture-MS Homo sapiens
443 NPTN 27020
Affinity Capture-MS Homo sapiens
444 CTNNB1 1499
Affinity Capture-MS Homo sapiens
445 IFNE  
Affinity Capture-Western Homo sapiens
446 MRGBP  
Affinity Capture-MS Homo sapiens
447 CCNJL  
Affinity Capture-MS Homo sapiens
448 NXNL2  
Affinity Capture-MS Homo sapiens
449 WDR59 79726
Affinity Capture-MS Homo sapiens
450 EPHA7 2045
Affinity Capture-MS Homo sapiens
451 AURKB 9212
Affinity Capture-MS Homo sapiens
452 CTSG 1511
Affinity Capture-MS Homo sapiens
453 FKBP5 2289
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
454 MAPK6  
Two-hybrid Homo sapiens
455 C12orf74  
Affinity Capture-MS Homo sapiens
456 XRCC6 2547
Proximity Label-MS Homo sapiens
457 GPR45  
Affinity Capture-MS Homo sapiens
458 A4GNT  
Affinity Capture-MS Homo sapiens
459 MAX  
Reconstituted Complex Homo sapiens
460 GZMB  
Biochemical Activity Homo sapiens
461 SF3B3 23450
Affinity Capture-MS Homo sapiens
462 VDAC1 7416
Co-fractionation Homo sapiens
463 TMPRSS5  
Affinity Capture-MS Homo sapiens
464 NANOG  
Affinity Capture-MS Homo sapiens
465 FBXW5  
Affinity Capture-MS Homo sapiens
466 C9orf72  
Affinity Capture-MS Homo sapiens
467 ARRB2 409
Affinity Capture-MS Homo sapiens
468 ADAM7  
Affinity Capture-MS Homo sapiens
469 SIRT6  
Affinity Capture-MS Homo sapiens
470 HAUS1  
Affinity Capture-MS Homo sapiens
471 FOXRED2  
Affinity Capture-MS Homo sapiens
472 SLC1A1 6505
Affinity Capture-MS Homo sapiens
473 TUBG1 7283
Affinity Capture-MS Homo sapiens
474 MFSD4  
Affinity Capture-MS Homo sapiens
475 OSTM1 28962
Affinity Capture-MS Homo sapiens
476 SMURF1 57154
Affinity Capture-MS Homo sapiens
477 MAP7D3 79649
Reconstituted Complex Homo sapiens
478 GZMH  
Affinity Capture-MS Homo sapiens
479 OTUD4  
Affinity Capture-MS Homo sapiens
480 C9orf173  
Affinity Capture-MS Homo sapiens
481 VWA2 340706
Affinity Capture-MS Homo sapiens
482 PINK1  
Affinity Capture-MS Homo sapiens
483 NDEL1 81565
Affinity Capture-Western Homo sapiens
484 WDR90  
Affinity Capture-MS Homo sapiens
485 ZUFSP 221302
Affinity Capture-MS Homo sapiens
486 WDR5B  
Affinity Capture-MS Homo sapiens
487 CXCR1  
Two-hybrid Homo sapiens
488 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
489 CAPN10  
Affinity Capture-MS Homo sapiens
490 TRAV20  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TUBA1A is involved
PathwayEvidenceSource
Activation of AMPK downstream of NMDARs IEA Reactome
Activation of NMDA receptors and postsynaptic events IEA Reactome
Adaptive Immune System TAS Reactome
Aggrephagy TAS Reactome
Aggrephagy IEA Reactome
Anchoring of the basal body to the plasma membrane TAS Reactome
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Asparagine N-linked glycosylation TAS Reactome
Assembly and cell surface presentation of NMDA receptors IEA Reactome
AURKA Activation by TPX2 TAS Reactome
Autophagy TAS Reactome
Autophagy IEA Reactome
Axon guidance TAS Reactome
Axon guidance IEA Reactome
Carboxyterminal post-translational modifications of tubulin IEA Reactome
Carboxyterminal post-translational modifications of tubulin TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Centrosome maturation TAS Reactome
Chaperonin-mediated protein folding IEA Reactome
Cilium Assembly TAS Reactome
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding IEA Reactome
COPI-dependent Golgi-to-ER retrograde traffic TAS Reactome
COPI-independent Golgi-to-ER retrograde traffic TAS Reactome
COPI-mediated anterograde transport TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
EML4 and NUDC in mitotic spindle formation TAS Reactome
ER to Golgi Anterograde Transport TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
Formation of tubulin folding intermediates by CCT/TriC IEA Reactome
G2/M Transition TAS Reactome
Gap junction assembly IEA Reactome
Gap junction assembly TAS Reactome
Gap junction trafficking IEA Reactome
Gap junction trafficking TAS Reactome
Gap junction trafficking and regulation IEA Reactome
Gap junction trafficking and regulation TAS Reactome
Golgi-to-ER retrograde transport TAS Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
Hedgehog 'off' state TAS Reactome
Hemostasis TAS Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Interferon Signaling TAS Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic TAS Reactome
Intraflagellar transport TAS Reactome
Kinesins TAS Reactome
L1CAM interactions TAS Reactome
L1CAM interactions IEA Reactome
Loss of Nlp from mitotic centrosomes TAS Reactome
Loss of proteins required for interphase microtubule organization from the centrosome TAS Reactome
M Phase TAS Reactome
Macroautophagy TAS Reactome
Macroautophagy IEA Reactome
Membrane Trafficking IEA Reactome
Membrane Trafficking TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of proteins TAS Reactome
MHC class II antigen presentation TAS Reactome
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Mitotic Prometaphase TAS Reactome
Nervous system development TAS Reactome
Nervous system development IEA Reactome
Neuronal System IEA Reactome
Neurotransmitter receptors and postsynaptic signal transmission IEA Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Organelle biogenesis and maintenance TAS Reactome
PKR-mediated signaling TAS Reactome
Post NMDA receptor activation events IEA Reactome
Post-chaperonin tubulin folding pathway IEA Reactome
Post-translational protein modification IEA Reactome
Post-translational protein modification TAS Reactome
Prefoldin mediated transfer of substrate to CCT/TriC IEA Reactome
Protein folding IEA Reactome
Recruitment of mitotic centrosome proteins and complexes TAS Reactome
Recruitment of NuMA to mitotic centrosomes TAS Reactome
Recycling pathway of L1 TAS Reactome
Recycling pathway of L1 IEA Reactome
Regulation of PLK1 Activity at G2/M Transition TAS Reactome
Resolution of Sister Chromatid Cohesion TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases Activate Formins TAS Reactome
RHO GTPases activate IQGAPs TAS Reactome
Sealing of the nuclear envelope (NE) by ESCRT-III TAS Reactome
Selective autophagy TAS Reactome
Selective autophagy IEA Reactome
Separation of Sister Chromatids TAS Reactome
Signal Transduction TAS Reactome
Signaling by Hedgehog TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
The role of GTSE1 in G2/M progression after G2 checkpoint TAS Reactome
Translocation of SLC2A4 (GLUT4) to the plasma membrane IEA Reactome
Transmission across Chemical Synapses IEA Reactome
Transport of connexons to the plasma membrane TAS Reactome
Transport to the Golgi and subsequent modification TAS Reactome
Vesicle-mediated transport IEA Reactome
Vesicle-mediated transport TAS Reactome
Viral Infection Pathways TAS Reactome





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